NEJM:甲状旁腺癌所致的桡骨骨折-病例报道

2018-10-11 xing.T MedSci原创

该患者前臂夹板固定6周,并接受维生素D和钙补充治疗。在骨折诊断后1年进行X线平片检查发现桡骨骨折部位融合以及正常的骨密度。

患者为一名45岁的男性,因左前臂疼痛而到骨科就诊,他在1天前抓栏杆时首次感觉到疼痛。

左臂的X线平片显示桡骨骨折(如图A箭头所示),以及桡骨和尺骨的弥漫性低密度、斑驳样表现。在就诊前两个月,患者被诊断为原发性甲状旁腺功能亢进,甲状旁腺激素水平为3590 pg/ml(参考范围为10-65),血清钙水平为13.0 mg/dl(3.25 mmol/L; 参考范围为8.5-10.2mg/dl[2.12-2.55 mmol/L]。他接受了甲状旁腺切除术,发现患有甲状旁腺癌,这是原发性甲状旁腺功能亢进的罕见原因,可表现为甲状旁腺激素水平显著升高。诊断时的评估显示没有转移性疾病的证据。



该患者前臂夹板固定6周,并接受维生素D和钙补充治疗。在骨折诊断后1年进行X线平片检查发现桡骨骨折部位融合以及正常的骨密度(如图B所示)。甲状旁腺切除术后一年,患者的甲状旁腺激素水平为48 pg/ml,钙水平为9.0 mg/dl(2.25 mmol/L)。

原始出处:

Taku Suzuki,et al.Radial Fracture Due to Parathyroid Carcinoma.N Engl J Med 2018; https://www.nejm.org/doi/full/10.1056/NEJMicm1710426

本文系梅斯医学(MedSci)原创编译整理,转载需授权!

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (3)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1452465, encodeId=3d87145246598, content=<a href='/topic/show?id=d90469826e2' target=_blank style='color:#2F92EE;'>#甲状旁腺#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=69826, encryptionId=d90469826e2, topicName=甲状旁腺)], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=84ba5566863, createdName=huperzia, createdTime=Fri Oct 12 22:36:00 CST 2018, time=2018-10-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1544273, encodeId=9bde15442e32c, content=<a href='/topic/show?id=a17b623e0fa' target=_blank style='color:#2F92EE;'>#桡骨#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62370, encryptionId=a17b623e0fa, topicName=桡骨)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=5cb713654306, createdName=ms920641618706883, createdTime=Fri Oct 12 22:36:00 CST 2018, time=2018-10-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=348856, encodeId=fe7b348856a8, content=嗯嗯,学习了。, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2018/07/16/3b24606172648eea459125cb74754afe.jpg, createdBy=6c022216608, createdName=liumin1987, createdTime=Thu Oct 11 08:53:05 CST 2018, time=2018-10-11, status=1, ipAttribution=)]
  2. [GetPortalCommentsPageByObjectIdResponse(id=1452465, encodeId=3d87145246598, content=<a href='/topic/show?id=d90469826e2' target=_blank style='color:#2F92EE;'>#甲状旁腺#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=69826, encryptionId=d90469826e2, topicName=甲状旁腺)], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=84ba5566863, createdName=huperzia, createdTime=Fri Oct 12 22:36:00 CST 2018, time=2018-10-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1544273, encodeId=9bde15442e32c, content=<a href='/topic/show?id=a17b623e0fa' target=_blank style='color:#2F92EE;'>#桡骨#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62370, encryptionId=a17b623e0fa, topicName=桡骨)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=5cb713654306, createdName=ms920641618706883, createdTime=Fri Oct 12 22:36:00 CST 2018, time=2018-10-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=348856, encodeId=fe7b348856a8, content=嗯嗯,学习了。, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2018/07/16/3b24606172648eea459125cb74754afe.jpg, createdBy=6c022216608, createdName=liumin1987, createdTime=Thu Oct 11 08:53:05 CST 2018, time=2018-10-11, status=1, ipAttribution=)]
  3. [GetPortalCommentsPageByObjectIdResponse(id=1452465, encodeId=3d87145246598, content=<a href='/topic/show?id=d90469826e2' target=_blank style='color:#2F92EE;'>#甲状旁腺#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=69826, encryptionId=d90469826e2, topicName=甲状旁腺)], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=84ba5566863, createdName=huperzia, createdTime=Fri Oct 12 22:36:00 CST 2018, time=2018-10-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1544273, encodeId=9bde15442e32c, content=<a href='/topic/show?id=a17b623e0fa' target=_blank style='color:#2F92EE;'>#桡骨#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62370, encryptionId=a17b623e0fa, topicName=桡骨)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=5cb713654306, createdName=ms920641618706883, createdTime=Fri Oct 12 22:36:00 CST 2018, time=2018-10-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=348856, encodeId=fe7b348856a8, content=嗯嗯,学习了。, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2018/07/16/3b24606172648eea459125cb74754afe.jpg, createdBy=6c022216608, createdName=liumin1987, createdTime=Thu Oct 11 08:53:05 CST 2018, time=2018-10-11, status=1, ipAttribution=)]
    2018-10-11 liumin1987

    嗯嗯,学习了。

    0