JAHA:左房功能和结构与室上性异位节律的关联

2021-02-06 MedSci原创 MedSci原创

LA功能受损和LA增大与动态心电图监测的PACs相关。室上性异位节律指标可提供有关心房肌病变程度的信息。

较高水平的室上性异位节律与更大的房颤、卒中和死亡风险相关。几乎没有关于室上性异位节律种族/民族差异的信息,另外,较高水平的室上性异位节律是否与受损的左心房(LA)功能和LA增大之间存在相关性的信息也很少。近日,血管疾病领域权威杂志JAHA上针对这些问题发表了一篇研究文章。

在动脉粥样硬化多民族研究(MESA)中,有1148名参与者(男性占47%;平均年龄为67岁)在2010年至2012年期间接受了心血管磁共振成像检查,随后在2016年至2018年期间进行了14天动态心电图监测。研究人员分析了参与者的特征和心血管磁共振上与每小时房性早搏(PACs)的平均计数和每天室上性心动过速平均次数有关的LA功能和结构指标。

在调整后的回归分析中,较大的年龄、男性、白人、升高的B-型钠钠肽前体N末端(NT-proBNP)以及临床检测到的房颤与每小时PACs增加有关。中国和西班牙裔参与者平均每小时的PACs少于白人参与者(中国参与者,减少了31%[95%CI为8%–49%];西班牙裔参与者减少了38%[95%CI为19%–52%] )。较高的LA总排空分数与每小时PAC减少有关(每个SD,每小时PAC减少16%[95%CI为7%–25%])。LA最小体积值越大,则每小时的PAC越多(每个SD,每小时PAC的数量增加为7%[95%CI为2%–13%])。LA体积与室上性心动过速/天的相关性在方向上相似,但关联性较弱。

由此可见,LA功能受损和LA增大与动态心电图监测的PACs相关。室上性异位节律指标可提供有关心房肌病变程度的信息

原始出处:

Susan R. Heckbert.et al.Associations of Left Atrial Function and Structure With Supraventricular Ectopy: The Multi‐Ethnic Study of Atherosclerosis.J AM HEART ASSOC.2021.https://www.ahajournals.org/doi/full/10.1161/JAHA.120.018093

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    2021-12-01 ms5000001012606609

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    2021-02-08 zhaohui6731
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