BMJ:欧洲年轻人结直肠癌发病率25年持续增加

2019-05-30 荷塘月影 医学论坛网

又胖又焦虑的小伙伴注意了。。 在一个生活条件越来越好的世界,我们却经常觉得焦虑不安,这些都是过于敏感的生存本能发挥了不必要的作用。


又胖又焦虑的小伙伴注意了。。

在一个生活条件越来越好的世界,我们却经常觉得焦虑不安,这些都是过于敏感的生存本能发挥了不必要的作用。

在生存本能的主导下,可能会导致我们陷入一些不良的行为模式,从而对我们的健康产生毁灭性的影响。

有人说“最大的原罪是懒惰”,饿了就去找吃的,能坐着就不站着。目前欧洲越来越多的年轻人受到结肠癌的影响。所为何故?

目的

50岁及以上人群直肠癌(CRC)发病率下降,年轻人群却出现了相反的趋势。欧洲尚缺乏年轻人CRC发病率的统计数据。因此,我们的目的是分析欧洲50岁以下人群的CRC发病率和死亡率趋势。

研究设计

我们从国家和地区癌症登记处检索1990年至2016年期间与年龄相关的CRC发病率和死亡率的数据。通过Joinpoint回归分析趋势并表示为年度百分比变化。

结果

我们检索了来自20个欧洲国家的1.437亿20-49岁人群的数据。其中,187 918(0.13%)被诊断患有CRC。从2004年到2016年,在20-29岁的受试者中,CRC发病率平均每年增加7.9%。从2005年到2016年,30-39岁年龄组的年增长率为4.9%,从2004年到2016年,40-49岁年龄组的年增长率为1.6%。这种增长最早发生在20-29岁的受试者中,10-20岁后的年龄在30-39岁和40-49岁之间。这与年龄群体现象一致。虽然大多数欧洲国家的CRC发病率上升,但各国之间有所不同。最年轻成年患者的CRC死亡率没有明显变化,但在1990年至2016年期间30-39岁每年下降1.1%,而在1990年至2009年期间,40-49岁每年下降2.4%。

结论

欧洲年轻人的CRC发病率上升,需要查明这一趋势的原因。临床医生应该意识到这种趋势。如果继续下去,可能需要考虑更改筛查指南。

原始出处:

Fanny ER, Stella AV, Marc B, et al. Increasingincidence of colorectal cancer in young adults in Europe over the last 25 years.GUT cancer. http://dx.doi.org/10.1136/gutjnl-2018-317592

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    2019-12-16 gaoxiaoe
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