Pediatrics:女性吸烟可导致婴儿突然死亡风险增加一倍

2019-03-12 国际循环编辑部 国际循环

一项大型研究发现,与母亲不吸烟的婴儿相比,妊娠期间每天吸一支烟的女性所生婴儿的突发意外婴儿死亡风险(SUID)是其母亲不吸烟风险的两倍多。当女性减少或戒烟时风险下降。

一项大型研究发现,与母亲不吸烟的婴儿相比,妊娠期间每天吸一支烟的女性所生婴儿的突发意外婴儿死亡风险(SUID)是其母亲不吸烟风险的两倍多。当女性减少或戒烟时风险下降。

研究者Tatiana M. Anderson博士指出,“与妊娠期间未减少吸烟的怀孕吸烟者(超过一半)相比,孕晚期吸烟数量减少的人SUID风险适度降低(12%),并且妊娠晚期的风险降低幅度更大(增加23%)”。

研究人员分析了20 685 463个出生和19 127个SUID的生命统计数据,校正母亲和父亲的种族和/或种族/西班牙裔,母亲和父亲的年龄,母亲的婚姻状况,母亲的教育,出生顺序,产前检查次数,妊娠周龄,分娩方法(阴道或剖腹产),婴儿性别和出生体重。SUID包括婴儿猝死综合症,床上意外窒息和窒息以及定义不明确的原因。

与不吸烟者相比,在妊娠期间报告任何吸烟的母亲婴儿中SUID的风险增加一倍以上(校正后比值比aOR=2.44;95%CI:2.31~2.57)。

研究结果表明,针对那些每天吸烟少于1包的人,而不是传统上有针对性的重度吸烟者(每天20支),努力戒烟可能对降低SUID率产生更大影响。超过一半(55%)在孕期吸烟的母亲继续吸烟的次数与妊娠前一样多。平均而言,在妊娠晚期开始戒烟的人(20%)将孕期吸烟的数量减少58%,而在妊娠晚期减少吸烟的人减少了33%的香烟数量。研究人员表示,这是“可衡量的减少”。

与继续吸烟者相比,减少吸烟组的SUID风险略低(aOR=0.88;95%CI:0.79~0.98),尽管戒烟组的风险降幅最大(aOR=0.77);95%CI:0.67~0.87)。与妊娠期间或之前3个月不吸烟相比,妊娠前吸烟和戒烟的母亲(aOR=1.47;95%CI:1.16~1.87)的SUID风险逐渐增加,妊娠前不吸烟但吸烟时妊娠的人(aOR=2.22;95%CI:1.15~4.29),以及孕前和孕期吸烟的人(aOR=2.52;95%CI:2.25~2.83)。仅在妊娠前吸烟的人,吸烟量似乎不影响SUID风险。

研究人员认为,吸烟评估可能保守,因为,他们没有评估产前或产后环境烟雾暴露,包括父亲吸烟,这已知会影响SUID风险。此外,吸烟估计依赖于妇女的报告,这些妇女可能不愿透露其吸烟状况。

最后,研究者指出,应“强烈鼓励”女性在妊娠期间不吸烟并减少吸烟量。如果女性不在妊娠期间吸烟,美国SUID率将降低22%。

原始出处
Tatiana M. Anderson, Juan M. Lavista Ferres, Shirley You Ren, et al. Maternal Smoking Before and During Pregnancy and the Risk of Sudden Unexpected Infant Death. Pediatrics. March 2019.

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    2019-09-02 feather89
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    2019-09-26 hbwxf
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    2019-04-10 zwjnj2

    学习学习学习

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    2019-03-16 清风拂面

    谢谢分享学习

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    2019-03-12 王秀

    学习了,涨知识了!

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    2019-03-12 一个字-牛

    学习了谢谢分享

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