Gastroenterology:克罗恩病缓解期患者食用红肉不会增加复发风险

2019-03-14 MedSci MedSci原创

研究认为,对于处于克罗恩病缓解期的患者,食用红肉及加工肉类不会增加其疾病复发风险

饮食可能是克罗恩病(CD)复发的重要因素。近日研究人员考察了减少红肉和加工肉消费对降低CD症状性复发风险的影响。

FACES研究中,处于缓解期的成年CD患者(sCDAI得分150以下),随机每周食用最少2份红肉或加工肉类(高消费组,n=118)或每月食用1份以下红肉或加工肉类(低消费组,n=96),持续49周。研究的主要终点为CD复发,定于sCDAI得分增加70-150分、手术或者CD药物干预。研究的次要终点为中重度复发,定义为sCDAI得分增加219分。

试验期间,高消费组实验依从性为98.5%,低消费组有18.8%的参与者未按要求食用红肉或加工肉。高消费组任何程度的CD复发率为62%,低消费组为42%。任何程度CD复发(P=0.61)或中重度复发(P=0.50)与红肉食用的时间长短无相关性。

研究认为,对于处于克罗恩病缓解期的患者,食用红肉及加工肉类不会增加其疾病复发风险。

原始出处:

L. Albenberg et al. A Diet Low in Red and Processed Meat Does Not Reduce Rate of Crohn's Disease Flares. Gastroenterology. March 11, 2019.

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    2019-09-15 许安
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