J Hypertens:复发性眩晕是高血压患者卒中的预测因子

2018-10-14 xing.T MedSci原创

由此可见,头晕的高血压患者在基线时没有高风险,但由于卒中死亡率较高,眩晕患者必须仔细随访多年。

头晕与高血压有关,但还有许多其他原因。近日,高血压领域权威杂志Journal of Hypertension上发表了一篇研究文章,该研究的目的是通过大型高血压患者队列来描述头晕的特征和临床相关性,并评估其对全因、血管卒中死亡率的预后价值。

20世纪70年代招募的OLD-HTA Lyon高血压患者队列中共有1716人根据头晕的有无进行分类。眩晕组被分为眩晕和不包含眩晕的其他头晕。

多元回归分析表明年龄、女性、冠状动脉疾病且无微量白蛋白尿可预测头晕。在30年随访期间,研究人员观察到956例患者死亡,其中508例患者死于心血管疾病,114例死于致命性急性卒中。在多变量Cox回归模型中,头晕对全因死亡风险[风险比为0.91; 95%CI为0.78-1.06]、心血管死亡率[风险比为0.86; 95%CI为0.70-1.05]或卒中死亡率[风险比为1.27; 95%CI为0.85-1.90]没有影响。在对不同眩晕亚组的分析中,只有眩晕对预后有影响。卒中死亡的风险增加特别显著,与无眩晕的患者相比其风险比为2.43(95%CI为1.33-4.46),与不包含眩晕的其他头晕的患者相比其风险比为2.22(95%CI为1.21-4.06)。

由此可见,头晕的高血压患者在基线时没有高风险,但由于卒中死亡率较高,眩晕患者必须仔细随访多年。

原始出处:

Courand, Pierre-Yves.et al. Recurrent vertigo is a predictor of stroke in a large cohort of hypertensive patients. Journal of Hypertension. 2018. https://journals.lww.com/jhypertension/Abstract/publishahead/Recurrent_vertigo_is_a_predictor_of_stroke_in_a.97323.aspx

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    2019-08-22 feather89
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    2018-10-16 医者仁心5538

    学习了

    0

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    2018-10-14 健健

    卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!

    0