Stroke:脑卒中后是瘫痪还是恢复独立行走?来看看这些因素的预测作用!

2021-07-15 MedSci原创 MedSci原创

卒中后年龄较小,皮质脊髓束完整,腿部力量良好,生活自理,无认知障碍,无视野缺损,坐姿良好,日常生活活动独立等所有因素可共同预测3个月后的独立行走的能力。

中风也叫做脑血管意外、脑卒中,是由于脑血管阻塞(缺血性中风)或者破裂(出血性中风)引起的脑组织供血障碍的病变。病情轻的可能只有头晕、手脚无力、共济失调,严重的则出现半身不遂、失语、吞咽困难甚至昏迷,抽搐,抢救不及时还会丧命。

急性脑卒中后约有三分之二的人会存在独立行走的困难,大部分幸存者在脑卒中后3个月仍有这种困难。因此在缺血性中风发病48小时后,只要心率、呼吸、血压、体温等生命体征平稳就可以开始康复训练,出血性中风需稍微晚一些。

其中,发病6个月尤其是3个月内是康复的最佳时间段,在这段时间内要抓紧时间进行系统康复,偏瘫、失语等功能障碍就有部分甚至全部恢复的可能。而从医疗服务的角度来看,独立行走对于康复目标和出院目的地的决策非常重要。因此,延迟独立行走会给脑卒中幸存者、其家庭和医疗系统带来巨大负担。

既往有一项系统回顾研究发现,年龄、糖尿病、中风严重程度、是否出血和右半脑卒中可预测患者恢复独立行走的能力。为了确定在中风后一个月内的非卧床患者中,哪些因素可以预测3、6和12个月后的独立行走。近日,来自澳大利亚堪培拉大学医院的专家在Stroke杂志上公布自己的研究成果。

在本研究中,独立行走被定义为在有或没有辅助工具且不需要外人帮助下行走共。纳入了15项研究,包括2344名中风后非卧床的参与者。7项研究的偏倚风险较低,8项研究的偏倚风险为中等。对2至4项研究进行了单独的荟萃分析,以计算12个预后因素的概率估计值的集合。

先验因素包括,参与者人口统计学:年龄、性别、手部;卒中前:高血压、缺血性心脏病、高胆固醇血症、糖尿病、心房颤动;卒中相关:卒中严重程度、卒中类型、缺血性卒中位置、卒中半球、溶栓,通过使用特定原因竞争风险Cox比例危险模型调查了与独立行走的关联。

3个月、6个月时预测独立行走的因素

结果显示,年龄较小(OR=3.4,P<0.001),完整的皮质脊髓束(OR=8.3,P<0.001),良好的腿部力量(OR=5.0,P<0.001),无认知障碍(OR=3.5,P<0.001),无视野缺损(OR=2. 4,P=0.006)、尿失禁(OR=2.3,P<0.001)、良好的坐姿(OR=7.9,P<0.001)和日常生活活动的独立性(OR=10.5,P<0.001)都可以预测3个月时可独立行走的能力。

同时,更年轻的年龄(OR=2.1,P<0.001)、延续性(OR=13.8,P<0.001)和良好的坐姿(OR=19.1,P<0.001)可以预测6个月时的独立行走。

综上,卒中后年龄较小,皮质脊髓束完整,腿部力量良好,生活自理,无认知障碍,无视野缺损,坐姿良好,日常生活活动独立等所有因素可共同预测3个月后的独立行走的能力。

 

参考文献:

Prediction of Independent Walking in People Who Are Nonambulatory Early After Stroke: A Systematic Review. Stroke. ;0:STROKEAHA.120.032345. https://doi.org/10.1161/STROKEAHA.120.032345

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    2021-07-16 ms2658711348342440

    谢谢 学习了

    0

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    2021-07-16 124c32bfm02暂无昵称

    非卧床患者中,哪些因素可以预测3、6和12个月后的独立行走

    0

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    2021-07-15 杰傲不逊

    卒中后年龄较小,皮质脊髓束完整,腿部力量良好,生活自理,无认知障碍,无视野缺损,坐姿良好,日常生活活动独立等所有因素可共同预测3个月后的独立行走的能力。

    0

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    2021-07-15 健健

    卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!

    0

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    2021-07-15 土豆你个马铃薯

    优秀故宫

    0

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    2021-07-15 249851524

    学习了

    0

拓展阅读

2017 卒中康复会议建议:卒中恢复的生物标志物

卒中康复中最难的临床问题是“患者的潜在康复能力是什么?”和“结合患者的临床表示,其最佳康复策略是什么?”没有回答这些问题,医生很难针对治疗的内容和重点做出决定。本文的主要目的是针对卒中康复标志物提供最新共识建议。

Stroke:社会经济地位影响卒中后功能障碍?

之前在社会经济剥夺程度与卒中后功能障碍关联方面的研究结果不一致,缺乏长期关联性的数据。我们通过年龄、性别、卒中前合并症和卒中表型这些方面来评估关联与差别。研究方法:我们采用伦敦南部卒中注册中心1995年至2011年间的数据进行队列研究,其中记录了所有伦敦西部各年龄患者首次发生卒中的案例。2104名患者在发生卒中3个月后仍在世。社会经济剥夺程度是通过以患者邮区号为基础的复合剥夺指数进行测量的,卒中后