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前列腺素或成为结肠癌肿瘤标记物

2016-01-06 史俊庭 王晓凡 中国科学报

前列腺素结肠癌赵玉洲李海涛刘康栋分子标记物河南省肿瘤医院《转化医学》
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近日，河南省肿瘤医院赵玉洲博士与中美（河南）荷美尔肿瘤研究院李海涛和刘康栋博士合作开展的研究表明，前列腺素中血栓素A2有望成为结肠癌筛查、预后判断、治疗效果检测的重要分子标记物。该研究成果发表在《转化医学》上。 研究人员将百余例调查人群分为健康人组、家族性结肠癌腺瘤病服用阿司匹林组和不服用阿司匹林组、结肠癌患者组四大类型，对其血浆、尿液、病理切片等物质进行分析发现，在家族性结肠息肉患者和

近日，河南省肿瘤医院赵玉洲博士与中美（河南）荷美尔肿瘤研究院李海涛和刘康栋博士合作开展的研究表明，前列腺素中血栓素A2有望成为结肠癌筛查、预后判断、治疗效果检测的重要分子标记物。该研究成果发表在《转化医学》上。

研究人员将百余例调查人群分为健康人组、家族性结肠癌腺瘤病服用阿司匹林组和不服用阿司匹林组、结肠癌患者组四大类型，对其血浆、尿液、病理切片等物质进行分析发现，在家族性结肠息肉患者和结肠癌患者中，前列腺素中的血栓素A2显著增加。

目前，癌胚抗原（CEA）、CA19-9、CA242等是临床中较为常见的几种大肠癌的肿瘤标记物。而此项研究则表明，血清中前列腺素的成分含量高低，将有可能成为新的结肠癌肿瘤标记物，通过血清检测，可作为诊断原发及复发性大肠癌的标志特异物，有助于提高结肠癌的诊断正确率。

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    2016-03-01 wjywjy

    #标记物#

    0

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    2016-12-15 makuansheng

    #前列腺素#

    0

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ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=52552, encodeId=4f5e52552bc, content=赞一个, beContent=null, objectType=article, channel=null, level=null, likeNumber=98, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRiaKicWybj5Q5KN7PWibALciaJ4W5bZwTlDSFRibFu87125pCq0IXePrC0mpbiasADRqL4NcjUoyQCT9De/0, createdBy=7c7e1636498, createdName=wzf990214, createdTime=Wed Jan 06 20:28:00 CST 2016, time=2016-01-06, status=1, ipAttribution=)]
    2016-08-27 李东泽

    这篇资讯带给我们新知识，启发新思维，不论是科研还是临床工作都有很大的帮助。。。

    0

  4. 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    2016-08-27 李东泽

    这篇资讯带给我们新知识，启发新思维，不论是科研还是临床工作都有很大的帮助。。。

    0

  5. 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ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=52552, encodeId=4f5e52552bc, content=赞一个, beContent=null, objectType=article, channel=null, level=null, likeNumber=98, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRiaKicWybj5Q5KN7PWibALciaJ4W5bZwTlDSFRibFu87125pCq0IXePrC0mpbiasADRqL4NcjUoyQCT9De/0, createdBy=7c7e1636498, createdName=wzf990214, createdTime=Wed Jan 06 20:28:00 CST 2016, time=2016-01-06, status=1, ipAttribution=)]
    2016-08-19 shalley66

    #肠癌肿瘤#

    0

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ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=52552, encodeId=4f5e52552bc, content=赞一个, beContent=null, objectType=article, channel=null, level=null, likeNumber=98, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRiaKicWybj5Q5KN7PWibALciaJ4W5bZwTlDSFRibFu87125pCq0IXePrC0mpbiasADRqL4NcjUoyQCT9De/0, createdBy=7c7e1636498, createdName=wzf990214, createdTime=Wed Jan 06 20:28:00 CST 2016, time=2016-01-06, status=1, ipAttribution=)]
    2016-05-18 lingaifan

    #肿瘤标记物#

    0

  7. 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createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzUn81b5CF5ibVPib8jWI92iciaxmqGHlwruOnK4SVZykd4iahqo1hicklIibyZoxm55X7EM8BW9eX1h1hQ2/0, createdBy=8aa81937526, createdName=李东泽, createdTime=Sat Aug 27 22:13:00 CST 2016, time=2016-08-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1808421, encodeId=72cd1808421ad, content=<a href='/topic/show?id=31388159892' target=_blank style='color:#2F92EE;'>#肠癌肿瘤#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=81598, encryptionId=31388159892, topicName=肠癌肿瘤)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f378286, createdName=shalley66, createdTime=Fri Aug 19 21:21:00 CST 2016, time=2016-08-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1931821, encodeId=bb6c1931821a9, content=<a href='/topic/show?id=7b6c829e4b8' target=_blank style='color:#2F92EE;'>#肿瘤标记物#</a>, 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content=有意思, beContent=null, objectType=article, channel=null, level=null, likeNumber=155, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRiaKicWybj5Q5KN7PWibALciaJ4W5bZwTlDSFRibFu87125pCq0IXePrC0mpbiasADRqL4NcjUoyQCT9De/0, createdBy=7c7e1636498, createdName=wzf990214, createdTime=Wed Jan 06 20:28:00 CST 2016, time=2016-01-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=52551, encodeId=50925255152, content=不错哦, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRiaKicWybj5Q5KN7PWibALciaJ4W5bZwTlDSFRibFu87125pCq0IXePrC0mpbiasADRqL4NcjUoyQCT9De/0, createdBy=7c7e1636498, createdName=wzf990214, createdTime=Wed Jan 06 20:28:00 CST 2016, time=2016-01-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=52552, encodeId=4f5e52552bc, content=赞一个, beContent=null, objectType=article, channel=null, level=null, likeNumber=98, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRiaKicWybj5Q5KN7PWibALciaJ4W5bZwTlDSFRibFu87125pCq0IXePrC0mpbiasADRqL4NcjUoyQCT9De/0, createdBy=7c7e1636498, createdName=wzf990214, createdTime=Wed Jan 06 20:28:00 CST 2016, time=2016-01-06, status=1, ipAttribution=)]
    2016-01-06 wzf990214

    牛

    0

  8. 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createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzUn81b5CF5ibVPib8jWI92iciaxmqGHlwruOnK4SVZykd4iahqo1hicklIibyZoxm55X7EM8BW9eX1h1hQ2/0, createdBy=8aa81937526, createdName=李东泽, createdTime=Sat Aug 27 22:13:00 CST 2016, time=2016-08-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1808421, encodeId=72cd1808421ad, content=<a href='/topic/show?id=31388159892' target=_blank style='color:#2F92EE;'>#肠癌肿瘤#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=81598, encryptionId=31388159892, topicName=肠癌肿瘤)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f378286, createdName=shalley66, createdTime=Fri Aug 19 21:21:00 CST 2016, time=2016-08-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1931821, encodeId=bb6c1931821a9, content=<a href='/topic/show?id=7b6c829e4b8' target=_blank style='color:#2F92EE;'>#肿瘤标记物#</a>, 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content=有意思, beContent=null, objectType=article, channel=null, level=null, likeNumber=155, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRiaKicWybj5Q5KN7PWibALciaJ4W5bZwTlDSFRibFu87125pCq0IXePrC0mpbiasADRqL4NcjUoyQCT9De/0, createdBy=7c7e1636498, createdName=wzf990214, createdTime=Wed Jan 06 20:28:00 CST 2016, time=2016-01-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=52551, encodeId=50925255152, content=不错哦, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRiaKicWybj5Q5KN7PWibALciaJ4W5bZwTlDSFRibFu87125pCq0IXePrC0mpbiasADRqL4NcjUoyQCT9De/0, createdBy=7c7e1636498, createdName=wzf990214, createdTime=Wed Jan 06 20:28:00 CST 2016, time=2016-01-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=52552, encodeId=4f5e52552bc, content=赞一个, beContent=null, objectType=article, channel=null, level=null, likeNumber=98, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRiaKicWybj5Q5KN7PWibALciaJ4W5bZwTlDSFRibFu87125pCq0IXePrC0mpbiasADRqL4NcjUoyQCT9De/0, createdBy=7c7e1636498, createdName=wzf990214, createdTime=Wed Jan 06 20:28:00 CST 2016, time=2016-01-06, status=1, ipAttribution=)]
    2016-01-06 wzf990214

    有意思

    0

  9. 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content=有意思, beContent=null, objectType=article, channel=null, level=null, likeNumber=155, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRiaKicWybj5Q5KN7PWibALciaJ4W5bZwTlDSFRibFu87125pCq0IXePrC0mpbiasADRqL4NcjUoyQCT9De/0, createdBy=7c7e1636498, createdName=wzf990214, createdTime=Wed Jan 06 20:28:00 CST 2016, time=2016-01-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=52551, encodeId=50925255152, content=不错哦, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRiaKicWybj5Q5KN7PWibALciaJ4W5bZwTlDSFRibFu87125pCq0IXePrC0mpbiasADRqL4NcjUoyQCT9De/0, createdBy=7c7e1636498, createdName=wzf990214, createdTime=Wed Jan 06 20:28:00 CST 2016, time=2016-01-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=52552, encodeId=4f5e52552bc, content=赞一个, beContent=null, objectType=article, channel=null, level=null, likeNumber=98, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRiaKicWybj5Q5KN7PWibALciaJ4W5bZwTlDSFRibFu87125pCq0IXePrC0mpbiasADRqL4NcjUoyQCT9De/0, createdBy=7c7e1636498, createdName=wzf990214, createdTime=Wed Jan 06 20:28:00 CST 2016, time=2016-01-06, status=1, ipAttribution=)]
    2016-01-06 wzf990214

    不错哦

    0

  10. 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createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzUn81b5CF5ibVPib8jWI92iciaxmqGHlwruOnK4SVZykd4iahqo1hicklIibyZoxm55X7EM8BW9eX1h1hQ2/0, createdBy=8aa81937526, createdName=李东泽, createdTime=Sat Aug 27 22:13:00 CST 2016, time=2016-08-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1808421, encodeId=72cd1808421ad, content=<a href='/topic/show?id=31388159892' target=_blank style='color:#2F92EE;'>#肠癌肿瘤#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=81598, encryptionId=31388159892, topicName=肠癌肿瘤)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f378286, createdName=shalley66, createdTime=Fri Aug 19 21:21:00 CST 2016, time=2016-08-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1931821, encodeId=bb6c1931821a9, content=<a href='/topic/show?id=7b6c829e4b8' target=_blank style='color:#2F92EE;'>#肿瘤标记物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=82974, encryptionId=7b6c829e4b8, topicName=肿瘤标记物)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2e07307, createdName=lingaifan, createdTime=Wed May 18 02:21:00 CST 2016, time=2016-05-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=52554, encodeId=638952554d5, content=牛, beContent=null, objectType=article, channel=null, level=null, likeNumber=98, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRiaKicWybj5Q5KN7PWibALciaJ4W5bZwTlDSFRibFu87125pCq0IXePrC0mpbiasADRqL4NcjUoyQCT9De/0, createdBy=7c7e1636498, createdName=wzf990214, createdTime=Wed Jan 06 20:29:00 CST 2016, time=2016-01-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=52550, encodeId=70ae5255038, content=有意思, beContent=null, objectType=article, channel=null, level=null, likeNumber=155, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRiaKicWybj5Q5KN7PWibALciaJ4W5bZwTlDSFRibFu87125pCq0IXePrC0mpbiasADRqL4NcjUoyQCT9De/0, createdBy=7c7e1636498, createdName=wzf990214, createdTime=Wed Jan 06 20:28:00 CST 2016, time=2016-01-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=52551, encodeId=50925255152, content=不错哦, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRiaKicWybj5Q5KN7PWibALciaJ4W5bZwTlDSFRibFu87125pCq0IXePrC0mpbiasADRqL4NcjUoyQCT9De/0, createdBy=7c7e1636498, createdName=wzf990214, createdTime=Wed Jan 06 20:28:00 CST 2016, time=2016-01-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=52552, encodeId=4f5e52552bc, content=赞一个, beContent=null, objectType=article, channel=null, level=null, likeNumber=98, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRiaKicWybj5Q5KN7PWibALciaJ4W5bZwTlDSFRibFu87125pCq0IXePrC0mpbiasADRqL4NcjUoyQCT9De/0, createdBy=7c7e1636498, createdName=wzf990214, createdTime=Wed Jan 06 20:28:00 CST 2016, time=2016-01-06, status=1, ipAttribution=)]
    2016-01-06 wzf990214

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