J Periodontol:牙周炎与血脂水平的关系

2017-09-10 MedSci MedSci原创

高血脂症是一种已知的心血管疾病的风险因素。对于系统性疾病如心血管疾病与牙周病之间关系的生物学机制已得到一定程度的了解。这篇研究的目的是为了检测血脂情况与牙周炎之间的联系。

高血脂症是一种已知的心血管疾病的风险因素。对于系统性疾病如心血管疾病与牙周病之间关系的生物学机制已得到一定程度的了解。这篇研究的目的是为了检测血脂情况与牙周炎之间的联系。

这项研究包含了6,905名年龄在20岁以上的韩国成年人。血脂水平数据不完整的研究个体,那些在2010和2012年韩国国家健康与营养调查过程中缺乏社区牙周指示系统评估的牙周炎检查结果,以及那些诊断糖尿病高血压和高血脂症的个体未纳入此项研究。所有分析都涉及复杂样本设计。研究使用多重逻辑回归分析的协变量调整评估血脂与牙周炎之间的联系。

结果显示,高密度脂蛋白(HDL)水平较低的女性罹患牙周炎的风险显著增高(比值比 [OR] 95% 置信区间 [CI]: 1.65(相对于最低组)),而那些低密度脂蛋白(LDL)水平较高的女性比高HDL和低LDL水平的女性罹患疾病的风险更高(OR (95% CI): 2.38 (1.01-5.60)相对于最高组)。在疾病风险与HDL和LDL水平间存在明显的剂量反应关系(p-趋势分别为0.001和0.039)。疾病风险与女性是否绝经不存在显著性差异。男性调查者中的血脂水平和牙周炎之间不存在任何明显的相关性。

结论:女性的低HDL和高LDL胆固醇水平与牙周炎存在明显的相关性。

原始出处:

Lee S, Im A, et al. Association Between Periodontitis With Blood Lipid Levels in Korean Population. J Periodontol. 2017 Sep 5:1-10. doi: 10.1902/jop.2017.170111.

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    2017-09-20 ren1mw

    学习一下!谢谢分享

    0

  4. 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channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160916/IMG57DBEDBBA66BD2947.jpg, createdBy=3b181951777, createdName=ren1mw, createdTime=Mon Sep 11 19:47:05 CST 2017, time=2017-09-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=242818, encodeId=f86624281828, content=学习了谢谢了, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLPeNmuNF9ibgMfMOAs7Iic5MpiaU8RLmRH67xCKuk5wzfhb7G4ib7ia6z9lrnsTicj1nAUfEOMecZDtvvu/0, createdBy=d7f91939785, createdName=186****0580(小山羊), createdTime=Mon Sep 11 09:49:01 CST 2017, time=2017-09-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=242615, encodeId=e04024261520, content=学习啦!谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLK1wzJZRTON4gxYUibhUyOypBwMibC4R7SsppicGhz5Ogoy0VVq4CWnqaD2Moeib8RWxI5lOiaVmnxpan/0, createdBy=c53f1730331, createdName=tanxingdoctor, createdTime=Sun Sep 10 20:34:04 CST 2017, time=2017-09-10, status=1, ipAttribution=)]
    2017-09-17 ren1mw

    学习一下!谢谢分享

    0

  5. 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channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160916/IMG57DBEDBBA66BD2947.jpg, createdBy=3b181951777, createdName=ren1mw, createdTime=Mon Sep 11 19:47:05 CST 2017, time=2017-09-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=242818, encodeId=f86624281828, content=学习了谢谢了, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLPeNmuNF9ibgMfMOAs7Iic5MpiaU8RLmRH67xCKuk5wzfhb7G4ib7ia6z9lrnsTicj1nAUfEOMecZDtvvu/0, createdBy=d7f91939785, createdName=186****0580(小山羊), createdTime=Mon Sep 11 09:49:01 CST 2017, time=2017-09-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=242615, encodeId=e04024261520, content=学习啦!谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLK1wzJZRTON4gxYUibhUyOypBwMibC4R7SsppicGhz5Ogoy0VVq4CWnqaD2Moeib8RWxI5lOiaVmnxpan/0, createdBy=c53f1730331, createdName=tanxingdoctor, createdTime=Sun Sep 10 20:34:04 CST 2017, time=2017-09-10, status=1, ipAttribution=)]
    2017-12-25 feather89
  6. 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content=学习啦!谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLK1wzJZRTON4gxYUibhUyOypBwMibC4R7SsppicGhz5Ogoy0VVq4CWnqaD2Moeib8RWxI5lOiaVmnxpan/0, createdBy=c53f1730331, createdName=tanxingdoctor, createdTime=Sun Sep 10 20:34:04 CST 2017, time=2017-09-10, status=1, ipAttribution=)]
    2017-09-12 ren1mw

    学习一下!谢谢分享!

    0

  7. 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  8. 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channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160916/IMG57DBEDBBA66BD2947.jpg, createdBy=3b181951777, createdName=ren1mw, createdTime=Mon Sep 11 19:47:05 CST 2017, time=2017-09-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=242818, encodeId=f86624281828, content=学习了谢谢了, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLPeNmuNF9ibgMfMOAs7Iic5MpiaU8RLmRH67xCKuk5wzfhb7G4ib7ia6z9lrnsTicj1nAUfEOMecZDtvvu/0, createdBy=d7f91939785, createdName=186****0580(小山羊), createdTime=Mon Sep 11 09:49:01 CST 2017, time=2017-09-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=242615, encodeId=e04024261520, content=学习啦!谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLK1wzJZRTON4gxYUibhUyOypBwMibC4R7SsppicGhz5Ogoy0VVq4CWnqaD2Moeib8RWxI5lOiaVmnxpan/0, createdBy=c53f1730331, createdName=tanxingdoctor, createdTime=Sun Sep 10 20:34:04 CST 2017, time=2017-09-10, status=1, ipAttribution=)]
    2017-09-11 ren1mw

    学习一下!谢谢分享

    0

  9. 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channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160916/IMG57DBEDBBA66BD2947.jpg, createdBy=3b181951777, createdName=ren1mw, createdTime=Mon Sep 11 19:47:05 CST 2017, time=2017-09-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=242818, encodeId=f86624281828, content=学习了谢谢了, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLPeNmuNF9ibgMfMOAs7Iic5MpiaU8RLmRH67xCKuk5wzfhb7G4ib7ia6z9lrnsTicj1nAUfEOMecZDtvvu/0, createdBy=d7f91939785, createdName=186****0580(小山羊), createdTime=Mon Sep 11 09:49:01 CST 2017, time=2017-09-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=242615, encodeId=e04024261520, content=学习啦!谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLK1wzJZRTON4gxYUibhUyOypBwMibC4R7SsppicGhz5Ogoy0VVq4CWnqaD2Moeib8RWxI5lOiaVmnxpan/0, createdBy=c53f1730331, createdName=tanxingdoctor, createdTime=Sun Sep 10 20:34:04 CST 2017, time=2017-09-10, status=1, ipAttribution=)]
    2017-09-11 186****0580(小山羊)

    学习了谢谢了

    0

  10. 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channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160916/IMG57DBEDBBA66BD2947.jpg, createdBy=3b181951777, createdName=ren1mw, createdTime=Mon Sep 11 19:47:05 CST 2017, time=2017-09-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=242818, encodeId=f86624281828, content=学习了谢谢了, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLPeNmuNF9ibgMfMOAs7Iic5MpiaU8RLmRH67xCKuk5wzfhb7G4ib7ia6z9lrnsTicj1nAUfEOMecZDtvvu/0, createdBy=d7f91939785, createdName=186****0580(小山羊), createdTime=Mon Sep 11 09:49:01 CST 2017, time=2017-09-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=242615, encodeId=e04024261520, content=学习啦!谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLK1wzJZRTON4gxYUibhUyOypBwMibC4R7SsppicGhz5Ogoy0VVq4CWnqaD2Moeib8RWxI5lOiaVmnxpan/0, createdBy=c53f1730331, createdName=tanxingdoctor, createdTime=Sun Sep 10 20:34:04 CST 2017, time=2017-09-10, status=1, ipAttribution=)]
    2017-09-10 tanxingdoctor

    学习啦!谢谢分享!

    0

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我们旨在评估未经常规牙周治疗的受试者根分叉(FI)与牙齿脱落之间的联系。

J Clin Periodontol:全身抗菌药物辅助牙周治疗对代谢综合征的影响:一项随机临床试验

研究基础牙周治疗(BPT)与抗菌药物(AM)对代谢综合征(MetS)的指标(腰围,收缩压/舒张压[BP],HDL-胆固醇,甘油三酯,葡萄糖)的影响。

J Periodontol:研究高脂饮食后小鼠牙槽骨变化和糖耐量受损的交叉作用

易感个体的高脂肪饮食(HFD),体重(BW)增加和葡萄糖耐量异常与牙槽骨吸收(ABL)有关。本实验使用协同交叉(CC)小鼠种群,研究遗传背景对HFD后牙槽骨变化和葡萄糖耐量的共同作用。

J Clin Periodontol:伴放线放线杆菌介导牙槽骨吸收时5-脂氧合酶的作用

白三烯(LT)是由5-脂氧合酶(5-LO)合成的促炎脂质介质。 5-LO代谢物参与牙周病(PD)的机制还不明确。本研究旨在评估5-LO在伴放线放线杆菌(Aggregatibacter Actinomycetemcomitans)(Aa)诱导的实验性PD中的作用。

J Clin Periodontol:不同抗生素方案治疗重度慢性牙周炎的1年随机试验

评估不同剂量的甲硝唑(MTZ)和MTZ +阿莫西林(AMX)治疗广泛性慢性牙周炎(GChP)的临床效果。