ARCH PATHOL LAB MED:转诊中心病理检查对阑尾肿瘤诊断和治疗的影响?

2020-06-25 MedSci原创 MedSci原创

关于阑尾肿瘤专科病理学审查的临床影响的数据目前仍较为有限。

关于阑尾肿瘤专科病理学审查的临床影响的数据目前仍较为有限。本研究试图

确定第三护理转诊中心胃肠病理学家的病理检查是否对阑尾肿瘤病变的诊断和临床处理有显著影响。

我们对2010年至2016年在加拿大安大略省三级护理转诊中心就诊的所有阑尾肿瘤患者进行了回顾性分析。记录原始病理报告与回顾病理报告之间的不一致率、不一致的性质以及任何不一致对病人管理的影响。

研究人员共发现145例阑尾病变患者(低度黏液性阑尾肿瘤[n = 79],浸润性黏液性腺癌[n = 12],“结直肠型”腺癌[n = 12],杯状细胞类癌和前杯状腺癌) 细胞类癌[n = 24]和其他病变/肿瘤[n = 20])。 在145例病例中,有36例(24.8%)发生了一种或多种诊断改变,其中相同的解释类别(n = 10),分期(n = 7),等级(n = 6)和分类解释( n = 5)是最常见的。 在36名患者中的10名(28%)中,诊断改变导致管理发生重大变化,包括建议进行额外的监护,全身化疗,额外的手术或中止监护。

阑尾肿瘤病变的专科病理学检查导致145例中的36例(24.8%)的诊断改变,其中近30%(36例中的10例)导致临床管理的改变。 临床上显著不一致的总发生率为7%(145个中的10个)。 我们的研究结果表明,转诊至专门中心的阑尾肿瘤的亚专科病理学检查是合理的。

原始出处:

Jolanta Jedrzkiewicz, MD; Yoko Tateishi, MD, PhD;Impact of Referral Center Pathology Review on Diagnosis and Management of Patients With Appendiceal Neoplasms

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    2020-07-17 yb6560
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    2021-01-23 docwu2019
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    2020-06-26 lqvr
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