J Rheumatol:幼年特发性关节炎颞下颌关节内异位骨形成的危险因素

2018-05-28 xiangting MedSci原创

接受IAC注射治疗TMJ关节炎的JIA患者中,TMJ内的HBF相对常见。

关节内注射糖皮质激素(IAC)常用于治疗幼年特发性关节炎(JIA)相关性颞下颌关节(TMJ)关节炎。IA治疗的一种潜在并发症是异位骨形成(HBF)。这项研究的目的是评估JIA儿童接受IA治疗TMJ关节炎后出现HBF的危险因素。

这是一项回顾性研究,纳入TMJ内IAC注射≥1次的JIA儿童。进行生存回归分析以确定出现HBF的危险因素。

共纳入238名儿童,其中33名(14%)出现HBF。在开始注射前没有HBF病例。单因素分析显示,发生HBF的危险因素是TMJ注射总数量和诊断为JIA时的年龄,而从JIA诊断到首次注射时间与HBF形成风险成反比。调整生存模型后,注射数量变得不再显著。HBF患儿急性或慢性改变的体检证据增多,即最大切口减小和下颌偏离可能性增加。

接受IAC注射治疗TMJ关节炎的JIA患者中,TMJ内的HBF相对常见。未来需要前瞻性研究,以描述注射本身造成的风险,而不是潜在的疾病活动,同时评估TMJ局部治疗的替代形式。

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    2019-04-10 xlysu
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    2018-06-30 fengyi819
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    2018-05-30 lmm397
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    2018-05-28 1ddf0692m34(暂无匿称)

    学习了.长知识

    0

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