JAAD:粘膜黑色素瘤的种族差异研究

2016-10-26 MedSci MedSci原创

根据最近发表在美国皮肤病学会杂志的研究结果,黏膜黑色素瘤的解剖部位和发展阶段存在民族与种族差异。研究人员使用的1988和2013之间的加利福尼亚的癌症登记处数据,对130920例皮肤黑色素瘤和1919例粘膜黑色素瘤患者进行了以人口为基础的研究。在非西班牙裔白人的黑色素瘤中,1%例是粘膜黑色素瘤;亚洲/太平洋岛民则是15%例是粘膜黑色素瘤;非西班牙裔黑人和西班牙裔的数值分别为9%和4%。粘膜黑色素瘤

根据最近发表在美国皮肤病学会杂志的研究结果,黏膜黑色素瘤的解剖部位和发展阶段存在民族与种族差异。

研究人员使用的1988和2013之间的加利福尼亚的癌症登记处数据,对130920例皮肤黑色素瘤和1919例粘膜黑色素瘤患者进行了以人口为基础的研究。

在非西班牙裔白人的黑色素瘤中,1%例是粘膜黑色素瘤;亚洲/太平洋岛民则是15%例是粘膜黑色素瘤;非西班牙裔黑人和西班牙裔的数值分别为9%和4%。

粘膜黑色素瘤最常见的部位是生殖泌尿(39.1%)、鼻和鼻窦(23.8%)、直肠(18.2%)和口腔(9.5%)。粘膜黑色素瘤患者中,72.6%例是非西班牙裔白人,2.6%为非西班牙裔黑人,15.2%是西班牙裔,9.7%是亚洲/太平洋岛民。

亚洲/太平洋女性岛民最有可能有肛门直肠黏膜黑色素瘤,而非西班牙白种人有泌尿生殖道黏膜黑色素瘤的比例最高,西班牙裔则最有可能患头颈部肿瘤。

亚洲/太平洋岛民的转移率最高。疾病的发展阶段也存在民族与种族差异。

“在非西班牙裔白人人群相比,发生在西班牙的黑色素瘤、亚洲/太平洋岛民和非西班牙裔黑人人口的粘膜黑色素瘤比例更大,而不是皮肤黑色素瘤,”研究人员写道。

“今后的工作重点应放在提高黏膜黑色素瘤的认识和筛查力度,同时研究基因和粘膜黑色素瘤的关系,为全身治疗带来希望。”

原始出处:

Mucosal melanomas differ by race, ethnicity.Healio.October 25, 2016

Altieri L, et al. J Am Acad Dermatol. 2016;doi:10.1016/j.jaad.2016.08.007.

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    2017-08-27 sunylz
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    2017-05-31 guoyibin
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    2016-11-11 虈亣靌

    讲的好,学习了

    0

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