SGLT-2抑制剂和GLP-1激动剂对成人2型糖尿病临床实践指南

2021-05-13 BMJ. 2021 May 11;373:n1091. doi: 10.1136/bmj.n1091.

临床问题 将钠-葡萄糖共转运蛋白2(SGLT-2)抑制剂和胰高血糖素样肽1(GLP-1)受体激动剂添加到成人2型糖尿病的常规护理(生活方式干预和/或其他糖尿病药物)中有哪些利弊? 2糖尿病有不同的心血

中文标题:

SGLT-2抑制剂和GLP-1激动剂对成人2型糖尿病临床实践指南

英文标题:

SGLT-2 inhibitors or GLP-1 receptor agonists for adults with type 2 diabetes: a clinical practice guideline.

发布机构:

发布日期:

2021-05-13

简要介绍:

临床问题 将钠-葡萄糖共转运蛋白2(SGLT-2)抑制剂和胰高血糖素样肽1(GLP-1)受体激动剂添加到成人2型糖尿病的常规护理(生活方式干预和/或其他糖尿病药物)中有哪些利弊? 2糖尿病有不同的心血管和肾脏结局风险吗? 当前实践 数十年来,血糖控制一直在指导有关2型糖尿病治疗的临床决策。 SGLT-2抑制剂和GLP-1受体激动剂传统上用于二甲双胍治疗后血糖水平升高的人群。 通过证明动脉粥样硬化性心血管疾病(CVD)和慢性肾脏疾病(CKD)的益处的试验已改变了这一点,而与药物降低血糖的潜力无关。

相关资料下载:
[AttachmentFileName(sort=1, fileName=66.pdf)] GetToolGuiderByIdResponse(projectId=1, id=487761c00209e20e, title=SGLT-2抑制剂和GLP-1激动剂对成人2型糖尿病临床实践指南, enTitle=SGLT-2 inhibitors or GLP-1 receptor agonists for adults with type 2 diabetes: a clinical practice guideline., guiderFrom=BMJ. 2021 May 11;373:n1091. doi: 10.1136/bmj.n1091., authorId=0, author=, summary=临床问题 将钠-葡萄糖共转运蛋白2(SGLT-2)抑制剂和胰高血糖素样肽1(GLP-1)受体激动剂添加到成人2型糖尿病的常规护理(生活方式干预和/或其他糖尿病药物)中有哪些利弊? 2糖尿病有不同的心血, cover=, journalId=0, articlesId=null, associationId=0, associationName=, associationIntro=, copyright=0, guiderPublishedTime=Thu May 13 00:00:00 CST 2021, originalUrl=, linkOutUrl=, content=<p><span class="VIiyi" lang="zh-CN"><span class="JLqJ4b ChMk0b" data-language-for-alternatives="zh-CN" data-language-to-translate-into="en" data-phrase-index="0">临床问题</span> <span class="JLqJ4b ChMk0b" data-language-for-alternatives="zh-CN" data-language-to-translate-into="en" data-phrase-index="2">将钠-葡萄糖共转运蛋白2(SGLT-2)抑制剂和胰高血糖素样肽1(GLP-1)受体激动剂添加到成人2型糖尿病的常规护理(生活方式干预和/或其他糖尿病药物)中有哪些利弊?</span> <span class="JLqJ4b ChMk0b" data-language-for-alternatives="zh-CN" data-language-to-translate-into="en" data-phrase-index="3">2糖尿病有不同的心血管和肾脏结局风险吗?</span> <span class="JLqJ4b ChMk0b" data-language-for-alternatives="zh-CN" data-language-to-translate-into="en" data-phrase-index="5">当前实践</span> <span class="JLqJ4b ChMk0b" data-language-for-alternatives="zh-CN" data-language-to-translate-into="en" data-phrase-index="7">数十年来,血糖控制一直在指导有关2型糖尿病治疗的临床决策。</span> <span class="JLqJ4b ChMk0b" data-language-for-alternatives="zh-CN" data-language-to-translate-into="en" data-phrase-index="8">SGLT-2抑制剂和GLP-1受体激动剂传统上用于二甲双胍治疗后血糖水平升高的人群。</span> <span class="JLqJ4b ChMk0b" data-language-for-alternatives="zh-CN" data-language-to-translate-into="en" data-phrase-index="9">通过证明动脉粥样硬化性心血管疾病(CVD)和慢性肾脏疾病(CKD)的益处的试验已改变了这一点,而与药物降低血糖的潜力无关。</span></span></p>, tagList=[TagDto(tagId=216, tagName=糖尿病)], categoryList=[CategoryDto(categoryId=6, categoryName=内分泌科, tenant=100), CategoryDto(categoryId=8, categoryName=糖尿病, tenant=100), CategoryDto(categoryId=85, categoryName=指南&解读, tenant=100), CategoryDto(categoryId=21100, categoryName=达仁堂循证e学界, tenant=100)], articleKeywordId=0, articleKeyword=, articleKeywordNum=6, guiderKeywordId=0, guiderKeyword=, guiderKeywordNum=6, haveAttachments=1, attachmentList=null, guiderType=0, guiderArea=指南, guiderLanguage=1, guiderRegion=3, opened=0, paymentType=, paymentAmount=10, recommend=0, recommendEndTime=null, sticky=0, stickyEndTime=null, allHits=19299, appHits=367, showAppHits=0, pcHits=656, showPcHits=18931, likes=5, shares=44, comments=20, approvalStatus=1, publishedTime=Thu May 13 21:25:25 CST 2021, publishedTimeString=2021-05-13, pcVisible=1, appVisible=1, editorId=4754896, editor=fbzhang, waterMark=0, formatted=0, memberCards=[], isPrivilege=0, deleted=0, version=2, createdBy=null, createdName=fbzhang, createdTime=Thu May 13 21:24:33 CST 2021, updatedBy=4754896, updatedName=fbzhang, updatedTime=Sat Jan 06 19:57:47 CST 2024, courseDetails=[], otherVersionGuiders=[], isGuiderMember=false, ipAttribution=, attachmentFileNameList=[AttachmentFileName(sort=1, fileName=66.pdf)])
66.pdf
下载请点击:
评论区 (16)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1234815, encodeId=62da1234815fc, content=学习了,还需要慢慢消化, beContent=null, objectType=guider, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=dd768250122, createdName=ms7000000672594991, createdTime=Tue Jul 26 10:16:21 CST 2022, time=2022-07-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1074669, encodeId=8b8010e4669fd, content=学习, beContent=null, objectType=guider, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=60fc5649540, createdName=ms3000000343741962, createdTime=Sun Nov 28 00:05:15 CST 2021, time=2021-11-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1073072, encodeId=65a610e3072c0, content=评论, beContent=null, objectType=guider, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/ajNVdqHZLLCrSITpN0DzicibhsHP4JubUaVSiaIeEZksPXLOibjrguLdBHtNI99Wib4LtNV0SFl71ibfiayO1axkp8edQ/132, createdBy=28512328442, createdName=XDuLog, createdTime=Tue Nov 23 07:16:05 CST 2021, time=2021-11-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1069924, encodeId=de05106992420, content=学习了, beContent=null, objectType=guider, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c8925696376, createdName=ms8000000011711218, createdTime=Sat Nov 13 17:27:14 CST 2021, time=2021-11-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1067037, encodeId=a3ad106e03742, content=学习, beContent=null, objectType=guider, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ef2c1960942, createdName=1e1366a1m07(暂无匿称), createdTime=Thu Nov 04 20:37:22 CST 2021, time=2021-11-04, status=1, ipAttribution=)]
    2022-07-26 ms7000000672594991

    学习了,还需要慢慢消化

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=1234815, encodeId=62da1234815fc, content=学习了,还需要慢慢消化, beContent=null, objectType=guider, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=dd768250122, createdName=ms7000000672594991, createdTime=Tue Jul 26 10:16:21 CST 2022, time=2022-07-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1074669, encodeId=8b8010e4669fd, content=学习, beContent=null, objectType=guider, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=60fc5649540, createdName=ms3000000343741962, createdTime=Sun Nov 28 00:05:15 CST 2021, time=2021-11-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1073072, encodeId=65a610e3072c0, content=评论, beContent=null, objectType=guider, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/ajNVdqHZLLCrSITpN0DzicibhsHP4JubUaVSiaIeEZksPXLOibjrguLdBHtNI99Wib4LtNV0SFl71ibfiayO1axkp8edQ/132, createdBy=28512328442, createdName=XDuLog, createdTime=Tue Nov 23 07:16:05 CST 2021, time=2021-11-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1069924, encodeId=de05106992420, content=学习了, beContent=null, objectType=guider, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c8925696376, createdName=ms8000000011711218, createdTime=Sat Nov 13 17:27:14 CST 2021, time=2021-11-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1067037, encodeId=a3ad106e03742, content=学习, beContent=null, objectType=guider, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ef2c1960942, createdName=1e1366a1m07(暂无匿称), createdTime=Thu Nov 04 20:37:22 CST 2021, time=2021-11-04, status=1, ipAttribution=)]
    2021-11-28 ms3000000343741962

    学习

    0

  3. [GetPortalCommentsPageByObjectIdResponse(id=1234815, encodeId=62da1234815fc, content=学习了,还需要慢慢消化, beContent=null, objectType=guider, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=dd768250122, createdName=ms7000000672594991, createdTime=Tue Jul 26 10:16:21 CST 2022, time=2022-07-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1074669, encodeId=8b8010e4669fd, content=学习, beContent=null, objectType=guider, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=60fc5649540, createdName=ms3000000343741962, createdTime=Sun Nov 28 00:05:15 CST 2021, time=2021-11-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1073072, encodeId=65a610e3072c0, content=评论, beContent=null, objectType=guider, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/ajNVdqHZLLCrSITpN0DzicibhsHP4JubUaVSiaIeEZksPXLOibjrguLdBHtNI99Wib4LtNV0SFl71ibfiayO1axkp8edQ/132, createdBy=28512328442, createdName=XDuLog, createdTime=Tue Nov 23 07:16:05 CST 2021, time=2021-11-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1069924, encodeId=de05106992420, content=学习了, beContent=null, objectType=guider, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c8925696376, createdName=ms8000000011711218, createdTime=Sat Nov 13 17:27:14 CST 2021, time=2021-11-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1067037, encodeId=a3ad106e03742, content=学习, beContent=null, objectType=guider, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ef2c1960942, createdName=1e1366a1m07(暂无匿称), createdTime=Thu Nov 04 20:37:22 CST 2021, time=2021-11-04, status=1, ipAttribution=)]
    2021-11-23 XDuLog

    评论

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=1234815, encodeId=62da1234815fc, content=学习了,还需要慢慢消化, beContent=null, objectType=guider, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=dd768250122, createdName=ms7000000672594991, createdTime=Tue Jul 26 10:16:21 CST 2022, time=2022-07-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1074669, encodeId=8b8010e4669fd, content=学习, beContent=null, objectType=guider, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=60fc5649540, createdName=ms3000000343741962, createdTime=Sun Nov 28 00:05:15 CST 2021, time=2021-11-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1073072, encodeId=65a610e3072c0, content=评论, beContent=null, objectType=guider, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/ajNVdqHZLLCrSITpN0DzicibhsHP4JubUaVSiaIeEZksPXLOibjrguLdBHtNI99Wib4LtNV0SFl71ibfiayO1axkp8edQ/132, createdBy=28512328442, createdName=XDuLog, createdTime=Tue Nov 23 07:16:05 CST 2021, time=2021-11-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1069924, encodeId=de05106992420, content=学习了, beContent=null, objectType=guider, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c8925696376, createdName=ms8000000011711218, createdTime=Sat Nov 13 17:27:14 CST 2021, time=2021-11-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1067037, encodeId=a3ad106e03742, content=学习, beContent=null, objectType=guider, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ef2c1960942, createdName=1e1366a1m07(暂无匿称), createdTime=Thu Nov 04 20:37:22 CST 2021, time=2021-11-04, status=1, ipAttribution=)]
    2021-11-13 ms8000000011711218

    学习了

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=1234815, encodeId=62da1234815fc, content=学习了,还需要慢慢消化, beContent=null, objectType=guider, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=dd768250122, createdName=ms7000000672594991, createdTime=Tue Jul 26 10:16:21 CST 2022, time=2022-07-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1074669, encodeId=8b8010e4669fd, content=学习, beContent=null, objectType=guider, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=60fc5649540, createdName=ms3000000343741962, createdTime=Sun Nov 28 00:05:15 CST 2021, time=2021-11-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1073072, encodeId=65a610e3072c0, content=评论, beContent=null, objectType=guider, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/ajNVdqHZLLCrSITpN0DzicibhsHP4JubUaVSiaIeEZksPXLOibjrguLdBHtNI99Wib4LtNV0SFl71ibfiayO1axkp8edQ/132, createdBy=28512328442, createdName=XDuLog, createdTime=Tue Nov 23 07:16:05 CST 2021, time=2021-11-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1069924, encodeId=de05106992420, content=学习了, beContent=null, objectType=guider, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c8925696376, createdName=ms8000000011711218, createdTime=Sat Nov 13 17:27:14 CST 2021, time=2021-11-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1067037, encodeId=a3ad106e03742, content=学习, beContent=null, objectType=guider, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ef2c1960942, createdName=1e1366a1m07(暂无匿称), createdTime=Thu Nov 04 20:37:22 CST 2021, time=2021-11-04, status=1, ipAttribution=)]
    2021-11-04 1e1366a1m07(暂无匿称)

    学习

    0