吗替麦考酚酯治疗免疫相关性皮肤病专家建议

2020-11-30 中国医师协会皮肤科医师分会 中华皮肤科杂志.2020,53(11):869-874.

吗替麦考酚酯可选择性抑制T、B淋巴细胞的增殖和活性,已广泛应用于多种免疫相关性皮肤病的治疗。在检索国内外文献的基础上,中国不同地域多位专家讨论和撰写了本建议。根据英国牛津大学循证医学中心制定的推荐等级

中文标题:

吗替麦考酚酯治疗免疫相关性皮肤病专家建议

发布日期:

2020-11-30

简要介绍:

吗替麦考酚酯可选择性抑制T、B淋巴细胞的增殖和活性,已广泛应用于多种免疫相关性皮肤病的治疗。在检索国内外文献的基础上,中国不同地域多位专家讨论和撰写了本建议。根据英国牛津大学循证医学中心制定的推荐等级标准,吗替麦考酚酯在成人中重度寻常型斑块状银屑病、成人大疱性类天疱疮和寻常型天疱疮的治疗中属于A级推荐;在成人系统性硬化症、成人中重度湿疹和中重度特应性皮炎的治疗中均属于B级推荐;在皮肤型红斑狼疮、皮肌炎、无肌病性皮肌炎、儿童系统性硬化症、儿童大疱性类天疱疮和儿童天疱疮、儿童中重度湿疹和特应性皮炎的治疗中属于C级推荐。

 

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评论区 (9)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1075696, encodeId=fe5f10e5696dc, content=嗯嗯, beContent=null, objectType=guider, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=70cc1777749, createdName=ms6250318294624163, createdTime=Wed Dec 01 07:12:39 CST 2021, time=2021-12-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1074437, encodeId=1af310e44372d, content=很实用, beContent=null, objectType=guider, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7b032176135, createdName=12061a47m22(暂无昵称), createdTime=Sat Nov 27 09:09:12 CST 2021, time=2021-11-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=977596, encodeId=75149e759692, content=6666, beContent=null, objectType=guider, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/hDibwguIM2NKZ3qEFg0XWBCjMiabUiaXKGTficllhQd6fiafL4b47NWR3oDhtVjPeRmqaRxCvDCWX5hHFFzIyqf12Vw/132, createdBy=afc85236729, createdName=18847b0d87m, createdTime=Mon Jun 28 15:32:03 CST 2021, time=2021-06-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=955656, encodeId=1e1195565610, content=666, beContent=null, objectType=guider, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d3345441563, createdName=ms5000000391980313, createdTime=Sat Apr 10 11:11:45 CST 2021, time=2021-04-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=953061, encodeId=74769530615d, content=学习啦, beContent=null, objectType=guider, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=aaf81711127, createdName=1dea3404m26(暂无匿称), createdTime=Thu Apr 01 14:28:35 CST 2021, time=2021-04-01, status=1, ipAttribution=)]
    2021-12-01 ms6250318294624163

    嗯嗯

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=1075696, encodeId=fe5f10e5696dc, content=嗯嗯, beContent=null, objectType=guider, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=70cc1777749, createdName=ms6250318294624163, createdTime=Wed Dec 01 07:12:39 CST 2021, time=2021-12-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1074437, encodeId=1af310e44372d, content=很实用, beContent=null, objectType=guider, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7b032176135, createdName=12061a47m22(暂无昵称), createdTime=Sat Nov 27 09:09:12 CST 2021, time=2021-11-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=977596, encodeId=75149e759692, content=6666, beContent=null, objectType=guider, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/hDibwguIM2NKZ3qEFg0XWBCjMiabUiaXKGTficllhQd6fiafL4b47NWR3oDhtVjPeRmqaRxCvDCWX5hHFFzIyqf12Vw/132, createdBy=afc85236729, createdName=18847b0d87m, createdTime=Mon Jun 28 15:32:03 CST 2021, time=2021-06-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=955656, encodeId=1e1195565610, content=666, beContent=null, objectType=guider, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d3345441563, createdName=ms5000000391980313, createdTime=Sat Apr 10 11:11:45 CST 2021, time=2021-04-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=953061, encodeId=74769530615d, content=学习啦, beContent=null, objectType=guider, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=aaf81711127, createdName=1dea3404m26(暂无匿称), createdTime=Thu Apr 01 14:28:35 CST 2021, time=2021-04-01, status=1, ipAttribution=)]
    2021-11-27 12061a47m22(暂无昵称)

    很实用

    0

  3. [GetPortalCommentsPageByObjectIdResponse(id=1075696, encodeId=fe5f10e5696dc, content=嗯嗯, beContent=null, objectType=guider, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=70cc1777749, createdName=ms6250318294624163, createdTime=Wed Dec 01 07:12:39 CST 2021, time=2021-12-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1074437, encodeId=1af310e44372d, content=很实用, beContent=null, objectType=guider, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7b032176135, createdName=12061a47m22(暂无昵称), createdTime=Sat Nov 27 09:09:12 CST 2021, time=2021-11-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=977596, encodeId=75149e759692, content=6666, beContent=null, objectType=guider, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/hDibwguIM2NKZ3qEFg0XWBCjMiabUiaXKGTficllhQd6fiafL4b47NWR3oDhtVjPeRmqaRxCvDCWX5hHFFzIyqf12Vw/132, createdBy=afc85236729, createdName=18847b0d87m, createdTime=Mon Jun 28 15:32:03 CST 2021, time=2021-06-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=955656, encodeId=1e1195565610, content=666, beContent=null, objectType=guider, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d3345441563, createdName=ms5000000391980313, createdTime=Sat Apr 10 11:11:45 CST 2021, time=2021-04-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=953061, encodeId=74769530615d, content=学习啦, beContent=null, objectType=guider, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=aaf81711127, createdName=1dea3404m26(暂无匿称), createdTime=Thu Apr 01 14:28:35 CST 2021, time=2021-04-01, status=1, ipAttribution=)]
    2021-06-28 18847b0d87m

    6666

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=1075696, encodeId=fe5f10e5696dc, content=嗯嗯, beContent=null, objectType=guider, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=70cc1777749, createdName=ms6250318294624163, createdTime=Wed Dec 01 07:12:39 CST 2021, time=2021-12-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1074437, encodeId=1af310e44372d, content=很实用, beContent=null, objectType=guider, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7b032176135, createdName=12061a47m22(暂无昵称), createdTime=Sat Nov 27 09:09:12 CST 2021, time=2021-11-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=977596, encodeId=75149e759692, content=6666, beContent=null, objectType=guider, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/hDibwguIM2NKZ3qEFg0XWBCjMiabUiaXKGTficllhQd6fiafL4b47NWR3oDhtVjPeRmqaRxCvDCWX5hHFFzIyqf12Vw/132, createdBy=afc85236729, createdName=18847b0d87m, createdTime=Mon Jun 28 15:32:03 CST 2021, time=2021-06-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=955656, encodeId=1e1195565610, content=666, beContent=null, objectType=guider, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d3345441563, createdName=ms5000000391980313, createdTime=Sat Apr 10 11:11:45 CST 2021, time=2021-04-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=953061, encodeId=74769530615d, content=学习啦, beContent=null, objectType=guider, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=aaf81711127, createdName=1dea3404m26(暂无匿称), createdTime=Thu Apr 01 14:28:35 CST 2021, time=2021-04-01, status=1, ipAttribution=)]
    2021-04-10 ms5000000391980313

    666

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=1075696, encodeId=fe5f10e5696dc, content=嗯嗯, beContent=null, objectType=guider, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=70cc1777749, createdName=ms6250318294624163, createdTime=Wed Dec 01 07:12:39 CST 2021, time=2021-12-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1074437, encodeId=1af310e44372d, content=很实用, beContent=null, objectType=guider, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7b032176135, createdName=12061a47m22(暂无昵称), createdTime=Sat Nov 27 09:09:12 CST 2021, time=2021-11-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=977596, encodeId=75149e759692, content=6666, beContent=null, objectType=guider, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/hDibwguIM2NKZ3qEFg0XWBCjMiabUiaXKGTficllhQd6fiafL4b47NWR3oDhtVjPeRmqaRxCvDCWX5hHFFzIyqf12Vw/132, createdBy=afc85236729, createdName=18847b0d87m, createdTime=Mon Jun 28 15:32:03 CST 2021, time=2021-06-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=955656, encodeId=1e1195565610, content=666, beContent=null, objectType=guider, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d3345441563, createdName=ms5000000391980313, createdTime=Sat Apr 10 11:11:45 CST 2021, time=2021-04-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=953061, encodeId=74769530615d, content=学习啦, beContent=null, objectType=guider, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=aaf81711127, createdName=1dea3404m26(暂无匿称), createdTime=Thu Apr 01 14:28:35 CST 2021, time=2021-04-01, status=1, ipAttribution=)]
    2021-04-01 1dea3404m26(暂无匿称)

    学习啦

    0