2020 EBMT实践建议:造血干细胞移植治疗FLT3基因内部串联复制的急性髓系白血病

2020-04-02 欧洲血液和骨髓移植小组 Haematologica. 2020 Apr 2.

约有25%-30%的急性髓系白血病患者存在类FMS酪氨酸激酶3(FLT3)基因突变,由于FLT3基因内部串联复制突变提示预后不良,异基因造血干细胞移植通常在首次完全缓解时进行。本文主要针对造血干细胞移

中文标题:

2020 EBMT实践建议:造血干细胞移植治疗FLT3基因内部串联复制的急性髓系白血病

英文标题:

Clinical practice recommendation on hematopoietic stem cell transplantation for acute myeloid leukemia patients with FLT3 internal tandem duplication: a position statement from the Acute Leukemia Working Party of the European Society for Blood and Marrow Transplantation

发布日期:

2020-04-02

简要介绍:

约有25%-30%的急性髓系白血病患者存在类FMS酪氨酸激酶3(FLT3)基因突变,由于FLT3基因内部串联复制突变提示预后不良,异基因造血干细胞移植通常在首次完全缓解时进行。本文主要针对造血干细胞移植治疗FLT3基因内部串联复制的急性髓系白血病提供指导。

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