低级别浆液性卵巢癌的专家共识(2020年版)

2020-04-30 妇产科相关专家组(统称) 中国癌症防治杂志.2020,12(2):117-125.

低级别浆液性卵巢癌(low-grade serous ovarian carcinoma,LGSOC)是一种少见的卵巢癌亚型,约占浆液性卵巢癌的6%~10%,其临床和分子生物学特性与高级别浆液性卵巢癌

中文标题:

低级别浆液性卵巢癌的专家共识(2020年版)

发布日期:

2020-04-30

简要介绍:

低级别浆液性卵巢癌(low-grade serous ovarian carcinoma,LGSOC)是一种少见的卵巢癌亚型,约占浆液性卵巢癌的6%~10%,其临床和分子生物学特性与高级别浆液性卵巢癌(high-grade serous ovarian carcinoma,HGSOC) 不同。LGSOC 通常继发于浆液性交界性肿瘤(serous borderline tumours,SBOT),表现为较高的KRAS、BRAF、ERBB2、NRAS 基因突变与表达,多见于年轻女性,临床病程较长,预后较好,但容易产生化疗耐药。手术是LGSOC 的主要治疗手段,ⅠC-Ⅳ期LGSOC 患者初期手术治疗后选择铂类/紫杉醇联合化疗。激素治疗和靶向治疗可能发挥重要作用,部分患者尤其是治疗结束后有残留病灶者可能受益于化疗后的激素维持治疗,其中贝伐珠单抗联合化疗可能提高复发性LGSOC 治疗反应率,而MEK 抑制剂等靶向治疗是LGSOC 治疗的方向。

 

相关资料下载:
[AttachmentFileName(sort=1, fileName=低级别浆液性卵巢癌的专家共识_2020年版_张爱凤.pdf)] GetToolGuiderByIdResponse(projectId=1, id=413581c001909285, title=低级别浆液性卵巢癌的专家共识(2020年版), enTitle=, guiderFrom=中国癌症防治杂志.2020,12(2):117-125., authorId=0, author=, summary=低级别浆液性卵巢癌(low-grade serous ovarian carcinoma,LGSOC)是一种少见的卵巢癌亚型,约占浆液性卵巢癌的6%~10%,其临床和分子生物学特性与高级别浆液性卵巢癌, cover=https://img.medsci.cn/2020525/1590341766360_2020535.jpg, journalId=0, articlesId=null, associationId=922, associationName=妇产科相关专家组(统称), associationIntro=null, copyright=0, guiderPublishedTime=Thu Apr 30 00:00:00 CST 2020, originalUrl=, linkOutUrl=, content=<div class="one_info2" style="color: #373737;"> <div id="all_content"> <div class="editor_mirror editor_mirror_del"> <p>低级别浆液性卵巢癌(low-grade serous ovarian carcinoma,LGSOC)是一种少见的卵巢癌亚型,约占浆液性卵巢癌的6%~10%,其临床和分子生物学特性与高级别浆液性卵巢癌(high-grade serous ovarian carcinoma,HGSOC) 不同。LGSOC 通常继发于浆液性交界性肿瘤(serous borderline tumours,SBOT),表现为较高的KRAS、BRAF、ERBB2、NRAS 基因突变与表达,多见于年轻女性,临床病程较长,预后较好,但容易产生化疗耐药。手术是LGSOC 的主要治疗手段,ⅠC-Ⅳ期LGSOC 患者初期手术治疗后选择铂类/紫杉醇联合化疗。激素治疗和靶向治疗可能发挥重要作用,部分患者尤其是治疗结束后有残留病灶者可能受益于化疗后的激素维持治疗,其中贝伐珠单抗联合化疗可能提高复发性LGSOC 治疗反应率,而MEK 抑制剂等靶向治疗是LGSOC 治疗的方向。</p> </div> </div> </div> <div class="box_info" style="color: #373737;">&nbsp;</div>, tagList=[TagDto(tagId=103624, tagName=低级别浆液性卵巢癌)], categoryList=[CategoryDto(categoryId=5, categoryName=肿瘤科, tenant=100), CategoryDto(categoryId=36, categoryName=妇产科, tenant=100), CategoryDto(categoryId=85, categoryName=指南&解读, tenant=100), CategoryDto(categoryId=20620, categoryName=肿瘤医学网, tenant=100), CategoryDto(categoryId=21052, categoryName=梅斯医学-卵巢癌网, tenant=100), CategoryDto(categoryId=21100, categoryName=达仁堂循证e学界, tenant=100)], articleKeywordId=0, articleKeyword=, articleKeywordNum=6, guiderKeywordId=359, guiderKeyword=卵巢癌, guiderKeywordNum=6, haveAttachments=1, attachmentList=null, guiderType=0, guiderArea=共识, guiderLanguage=0, guiderRegion=3, opened=0, paymentType=, paymentAmount=10, recommend=0, recommendEndTime=null, sticky=0, stickyEndTime=null, allHits=4952, appHits=364, showAppHits=288, pcHits=1645, showPcHits=4808, likes=1, shares=19, comments=7, approvalStatus=1, publishedTime=Mon May 25 01:44:51 CST 2020, publishedTimeString=2020-04-30, pcVisible=1, appVisible=1, editorId=2020535, editor=qiushida2, waterMark=0, formatted=0, memberCards=[], isPrivilege=0, deleted=0, version=2, createdBy=null, createdName=qiushida2, createdTime=Mon May 25 01:36:10 CST 2020, updatedBy=2020535, updatedName=qiushida2, updatedTime=Sat Jan 06 09:55:52 CST 2024, courseDetails=[], otherVersionGuiders=[], isGuiderMember=false, ipAttribution=, attachmentFileNameList=[AttachmentFileName(sort=1, fileName=低级别浆液性卵巢癌的专家共识_2020年版_张爱凤.pdf)])
低级别浆液性卵巢癌的专家共识_2020年版_张爱凤.pdf
下载请点击:
评论区 (6)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=968009, encodeId=91fd968009a6, content=学习了, beContent=null, objectType=guider, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRqG3l8Ohxg7pzwwK27vkqzGeRNsrTU7H234icQhkas8uWz4rXXrek1UYqbZtUmLMmZjl2icL0ibFuvY/0, createdBy=b6842032162, createdName=5474, createdTime=Sun May 23 21:16:41 CST 2021, time=2021-05-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=922143, encodeId=0cf0922143f9, content=想看全文。, beContent=null, objectType=guider, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=35215391000, createdName=ms9000001166668150, createdTime=Tue Feb 02 10:30:04 CST 2021, time=2021-02-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=909944, encodeId=17f1909944fe, content=转给朋友, beContent=null, objectType=guider, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5b172565856, createdName=12571e9dm53暂无昵称, createdTime=Tue Dec 22 07:02:35 CST 2020, time=2020-12-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=896288, encodeId=cb0f89628885, content=学习了 , beContent=null, objectType=guider, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKBt2XIYsVlqwNHibnch29hhCgEGYNJYBtcRLwjG9b3WpWvAJREwSibAOlQhllhjIpe4j9nbhyPlcnQ/132, createdBy=e40a2167558, createdName=coconut是我, createdTime=Mon Nov 02 16:38:44 CST 2020, time=2020-11-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=884998, encodeId=c3998849981c, content=学习了, beContent=null, objectType=guider, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a10c5416416, createdName=ms9000001304242802, createdTime=Sun Sep 13 19:39:38 CST 2020, time=2020-09-13, status=1, ipAttribution=)]
    2021-05-23 5474

    学习了

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=968009, encodeId=91fd968009a6, content=学习了, beContent=null, objectType=guider, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRqG3l8Ohxg7pzwwK27vkqzGeRNsrTU7H234icQhkas8uWz4rXXrek1UYqbZtUmLMmZjl2icL0ibFuvY/0, createdBy=b6842032162, createdName=5474, createdTime=Sun May 23 21:16:41 CST 2021, time=2021-05-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=922143, encodeId=0cf0922143f9, content=想看全文。, beContent=null, objectType=guider, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=35215391000, createdName=ms9000001166668150, createdTime=Tue Feb 02 10:30:04 CST 2021, time=2021-02-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=909944, encodeId=17f1909944fe, content=转给朋友, beContent=null, objectType=guider, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5b172565856, createdName=12571e9dm53暂无昵称, createdTime=Tue Dec 22 07:02:35 CST 2020, time=2020-12-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=896288, encodeId=cb0f89628885, content=学习了 , beContent=null, objectType=guider, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKBt2XIYsVlqwNHibnch29hhCgEGYNJYBtcRLwjG9b3WpWvAJREwSibAOlQhllhjIpe4j9nbhyPlcnQ/132, createdBy=e40a2167558, createdName=coconut是我, createdTime=Mon Nov 02 16:38:44 CST 2020, time=2020-11-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=884998, encodeId=c3998849981c, content=学习了, beContent=null, objectType=guider, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a10c5416416, createdName=ms9000001304242802, createdTime=Sun Sep 13 19:39:38 CST 2020, time=2020-09-13, status=1, ipAttribution=)]
    2021-02-02 ms9000001166668150

    想看全文。

    0

  3. [GetPortalCommentsPageByObjectIdResponse(id=968009, encodeId=91fd968009a6, content=学习了, beContent=null, objectType=guider, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRqG3l8Ohxg7pzwwK27vkqzGeRNsrTU7H234icQhkas8uWz4rXXrek1UYqbZtUmLMmZjl2icL0ibFuvY/0, createdBy=b6842032162, createdName=5474, createdTime=Sun May 23 21:16:41 CST 2021, time=2021-05-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=922143, encodeId=0cf0922143f9, content=想看全文。, beContent=null, objectType=guider, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=35215391000, createdName=ms9000001166668150, createdTime=Tue Feb 02 10:30:04 CST 2021, time=2021-02-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=909944, encodeId=17f1909944fe, content=转给朋友, beContent=null, objectType=guider, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5b172565856, createdName=12571e9dm53暂无昵称, createdTime=Tue Dec 22 07:02:35 CST 2020, time=2020-12-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=896288, encodeId=cb0f89628885, content=学习了 , beContent=null, objectType=guider, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKBt2XIYsVlqwNHibnch29hhCgEGYNJYBtcRLwjG9b3WpWvAJREwSibAOlQhllhjIpe4j9nbhyPlcnQ/132, createdBy=e40a2167558, createdName=coconut是我, createdTime=Mon Nov 02 16:38:44 CST 2020, time=2020-11-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=884998, encodeId=c3998849981c, content=学习了, beContent=null, objectType=guider, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a10c5416416, createdName=ms9000001304242802, createdTime=Sun Sep 13 19:39:38 CST 2020, time=2020-09-13, status=1, ipAttribution=)]
    2020-12-22 12571e9dm53暂无昵称

    转给朋友

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=968009, encodeId=91fd968009a6, content=学习了, beContent=null, objectType=guider, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRqG3l8Ohxg7pzwwK27vkqzGeRNsrTU7H234icQhkas8uWz4rXXrek1UYqbZtUmLMmZjl2icL0ibFuvY/0, createdBy=b6842032162, createdName=5474, createdTime=Sun May 23 21:16:41 CST 2021, time=2021-05-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=922143, encodeId=0cf0922143f9, content=想看全文。, beContent=null, objectType=guider, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=35215391000, createdName=ms9000001166668150, createdTime=Tue Feb 02 10:30:04 CST 2021, time=2021-02-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=909944, encodeId=17f1909944fe, content=转给朋友, beContent=null, objectType=guider, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5b172565856, createdName=12571e9dm53暂无昵称, createdTime=Tue Dec 22 07:02:35 CST 2020, time=2020-12-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=896288, encodeId=cb0f89628885, content=学习了 , beContent=null, objectType=guider, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKBt2XIYsVlqwNHibnch29hhCgEGYNJYBtcRLwjG9b3WpWvAJREwSibAOlQhllhjIpe4j9nbhyPlcnQ/132, createdBy=e40a2167558, createdName=coconut是我, createdTime=Mon Nov 02 16:38:44 CST 2020, time=2020-11-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=884998, encodeId=c3998849981c, content=学习了, beContent=null, objectType=guider, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a10c5416416, createdName=ms9000001304242802, createdTime=Sun Sep 13 19:39:38 CST 2020, time=2020-09-13, status=1, ipAttribution=)]
    2020-11-02 coconut是我

    学习了

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=968009, encodeId=91fd968009a6, content=学习了, beContent=null, objectType=guider, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRqG3l8Ohxg7pzwwK27vkqzGeRNsrTU7H234icQhkas8uWz4rXXrek1UYqbZtUmLMmZjl2icL0ibFuvY/0, createdBy=b6842032162, createdName=5474, createdTime=Sun May 23 21:16:41 CST 2021, time=2021-05-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=922143, encodeId=0cf0922143f9, content=想看全文。, beContent=null, objectType=guider, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=35215391000, createdName=ms9000001166668150, createdTime=Tue Feb 02 10:30:04 CST 2021, time=2021-02-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=909944, encodeId=17f1909944fe, content=转给朋友, beContent=null, objectType=guider, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5b172565856, createdName=12571e9dm53暂无昵称, createdTime=Tue Dec 22 07:02:35 CST 2020, time=2020-12-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=896288, encodeId=cb0f89628885, content=学习了 , beContent=null, objectType=guider, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKBt2XIYsVlqwNHibnch29hhCgEGYNJYBtcRLwjG9b3WpWvAJREwSibAOlQhllhjIpe4j9nbhyPlcnQ/132, createdBy=e40a2167558, createdName=coconut是我, createdTime=Mon Nov 02 16:38:44 CST 2020, time=2020-11-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=884998, encodeId=c3998849981c, content=学习了, beContent=null, objectType=guider, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a10c5416416, createdName=ms9000001304242802, createdTime=Sun Sep 13 19:39:38 CST 2020, time=2020-09-13, status=1, ipAttribution=)]
    2020-09-13 ms9000001304242802

    学习了

    0

拓展阅读

2010ESMO临床实践指南:非上皮性卵巢癌

欧洲肿瘤内科学会(ESMO,European Society for Medical Oncology) · 2010-03-01

2011 NICE 卵巢癌的诊断和起始治疗

英国国家卫生与临床优化研究所(NICE,National Institute for Health and Clinical Excellence) · 2011-01-01

2011 NICE Trabectedin治疗复发性卵巢癌

英国国家卫生与临床优化研究所(NICE,National Institute for Health and Clinical Excellence) · 2011-01-01

2012 ESMO临床实践指南:非上皮性卵巢癌的诊治与随访

欧洲肿瘤内科学会(ESMO,European Society for Medical Oncology) · 2012-06-01

2012 NSGC实践指南:遗传性乳腺癌和卵巢癌的风险评估和遗传咨询

国家遗传咨询师学会(NSGC,National Society of Genetic Counselors) · 2012-11-28

2013 FIGO 卵巢癌、输卵管癌、腹膜癌分期指南

国际妇产科联盟(FIGO,International Federation of Gynecology and Obstetrics) · 2013-10-22