高同型半胱氨酸血症诊疗专家共识

2020-09-09 中国营养学会 肿痼代谢与营养电子杂志.2020.7(3):283-288.

高同型半胱氨酸血症与多种疾病的发生发展, 如心脑血管疾病、髙血压、糖尿病、肾脏疾病、妊娠等疾病密切相关,几乎影响全身的各个器官, 通过氧化损伤、D N A 甲基化和含硫化合物代谢异常等多种机制影响细胞

中文标题:

高同型半胱氨酸血症诊疗专家共识

发布机构:

中国营养学会

发布日期:

2020-09-09

简要介绍:

高同型半胱氨酸血症与多种疾病的发生发展, 如心脑血管疾病、髙血压、糖尿病、肾脏疾病、妊娠等疾病密切相关,几乎影响全身的各个器官, 通过氧化损伤、D N A 甲基化和含硫化合物代谢异常等多种机制影响细胞的功能、蛋白质的合成与调控, 进而导致组织和器官的病理变化。总同型半胱氨酸代谢异常的诱因与基因、营养、疾病等关系密切, 因此, 本专家共识基于回顾分析近3 0 年的国内外研究文献和循证医学的证据, 结合我国人群特点, 本专家共识建议将总同型半胱氨酸定义为髙同型半胱氨酸血症; 根据同型半胱氨酸相关基因的检测结果和总同型半胱氨酸的水平, 通过调整饮食结构和/ 或使用膳食补充剂包括甜菜碱和B 族维生素以及相关辅助因子的营养素补充剂等方法降低总同型半胱氨酸水平, 以期显著减缓相关疾病的发展进程。推荐开展与同型半胱氨酸相关的检测指标, 以明确同型半胱氨酸升高的原因, 进而指导临床的精准干预措施,有效改善同型半胱氨酸水平, 实现预防疾病发生或延缓疾病进展的目的。

 

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    2022-07-01 知风123

    学习了

    0

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    2022-07-02 ms4000001809038213

    谢谢,学习了

    0

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    2022-05-11 huxuming0226

    好好学习

    0

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    2022-03-21 水流风

    学习了

    0

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    2022-03-16 fanzhanmi4422335

    学习了

    0

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