免疫检查点抑制剂治疗恶性肿瘤的PET/CT评价专家共识(2020版)

2020-09-30 中华医学会核医学分会 中华肿瘤杂志.2020.42(9):697-705.

免疫检查点抑制剂(ICIs)是恶性肿瘤治疗领域的重大突破,但由于其作用机制使然,出现了假性进展、超进展等特殊肿瘤应答模式,对临床治疗决策和疗效评价带来了困难与挑战。2017年,欧洲核医学年会根据已公布

中文标题:

免疫检查点抑制剂治疗恶性肿瘤的PET/CT评价专家共识(2020版)

发布日期:

2020-09-30

简要介绍:

免疫检查点抑制剂(ICIs)是恶性肿瘤治疗领域的重大突破,但由于其作用机制使然,出现了假性进展、超进展等特殊肿瘤应答模式,对临床治疗决策和疗效评价带来了困难与挑战。2017年,欧洲核医学年会根据已公布的临床试验数据,报道了应用18 F⁃FDG PET/ CT 评价肿瘤免疫治疗反应、判读免疫相关不良反应的优势。在中国,自2013 年正式开始ICIs 的临床研究以来,已有大量的研究数据产生,如何在肿瘤ICIs 治疗中合理、规范地应用PET/ CT 成为亟待解决的临床和科学问题。鉴于此,由中华医学会核医学分会PET 学组牵头,针对PET/ CT 检查规范、ICIs 治疗后PET/ CT 图像解读、疗效评价标准等内容,在结合文献、专家经验和委员会成员内部讨论的基础上,最终达成此共识,以期带动相应领域的技术普及与推广。

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