血清降钙素原检测在儿童感染性疾病中的临床应用专家共识

2019-01-30 中华医学会儿科学分会 中华儿科杂志.2019.57(1):9-15.

降钙素原(PCT)是早期、严重、侵袭性细菌感染的标志物,血清PCT<0.05 μg/L时多不支持细菌感染;血清PCT>2.00 μg/L需考虑脓毒症并提示病情严重;在进行结果判读时需注意结合临床表现,排除局部感染及非感染因素所致血清PCT升高;动态的血清PCT监测对病情的评估与预后判断非常重要,尤其在重症患儿。动态血清PCT监测可以指导临床抗菌药物使用,当血清PCT<0.25 μg/L排除细菌感染

中文标题:

血清降钙素原检测在儿童感染性疾病中的临床应用专家共识

发布日期:

2019-01-30

简要介绍:

降钙素原(PCT)是早期、严重、侵袭性细菌感染的标志物,血清PCT<0.05 μg/L时多不支持细菌感染;血清PCT>2.00 μg/L需考虑脓毒症并提示病情严重;在进行结果判读时需注意结合临床表现,排除局部感染及非感染因素所致血清PCT升高;动态的血清PCT监测对病情的评估与预后判断非常重要,尤其在重症患儿。动态血清PCT监测可以指导临床抗菌药物使用,当血清PCT<0.25 μg/L排除细菌感染时不使用抗菌药物;治疗后当血清PCT<0.50μg/L或峰值降低幅度≥80%,结合临床表现,可考虑停用抗茵药物。对于新生儿期血清PCT的判读需注意排除早期生理性升高及其他因素的影响。
 
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  1. [GetPortalCommentsPageByObjectIdResponse(id=2122522, encodeId=47672122522e0, content=不错,有用, beContent=null, objectType=guider, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/Ov8zW6cnDcSdRCdedRCVY3XAgRMNwodUG5ZsQUfHFmbO56KOJDdWSxWUxFwgh6HqbibkibFcm7RL1c9KaIuZ3SsQ/0, createdBy=846c2179273, createdName=Drfaith, createdTime=Wed Mar 29 17:45:27 CST 2023, time=2023-03-29, status=1, ipAttribution=湖南省), GetPortalCommentsPageByObjectIdResponse(id=952359, encodeId=641c9523591a, content=已转发给临床医生, beContent=null, objectType=guider, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210330/89ac79da9e2b46c49dd38698f891938b/15793a72df234d0090cbd82601754957.jpg, createdBy=a3f15387118, createdName=ms5000002143624482, createdTime=Tue Mar 30 13:13:25 CST 2021, time=2021-03-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=806911, encodeId=871580691193, content=有用, beContent=null, objectType=guider, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=66422891930, createdName=1023463763, createdTime=Sat Aug 08 11:18:37 CST 2020, time=2020-08-08, status=1, ipAttribution=)]
    2023-03-29 Drfaith 来自湖南省

    不错,有用

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=2122522, encodeId=47672122522e0, content=不错,有用, beContent=null, objectType=guider, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/Ov8zW6cnDcSdRCdedRCVY3XAgRMNwodUG5ZsQUfHFmbO56KOJDdWSxWUxFwgh6HqbibkibFcm7RL1c9KaIuZ3SsQ/0, createdBy=846c2179273, createdName=Drfaith, createdTime=Wed Mar 29 17:45:27 CST 2023, time=2023-03-29, status=1, ipAttribution=湖南省), GetPortalCommentsPageByObjectIdResponse(id=952359, encodeId=641c9523591a, content=已转发给临床医生, beContent=null, objectType=guider, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210330/89ac79da9e2b46c49dd38698f891938b/15793a72df234d0090cbd82601754957.jpg, createdBy=a3f15387118, createdName=ms5000002143624482, createdTime=Tue Mar 30 13:13:25 CST 2021, time=2021-03-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=806911, encodeId=871580691193, content=有用, beContent=null, objectType=guider, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=66422891930, createdName=1023463763, createdTime=Sat Aug 08 11:18:37 CST 2020, time=2020-08-08, status=1, ipAttribution=)]
    2021-03-30 ms5000002143624482

    已转发给临床医生

    0

  3. [GetPortalCommentsPageByObjectIdResponse(id=2122522, encodeId=47672122522e0, content=不错,有用, beContent=null, objectType=guider, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/Ov8zW6cnDcSdRCdedRCVY3XAgRMNwodUG5ZsQUfHFmbO56KOJDdWSxWUxFwgh6HqbibkibFcm7RL1c9KaIuZ3SsQ/0, createdBy=846c2179273, createdName=Drfaith, createdTime=Wed Mar 29 17:45:27 CST 2023, time=2023-03-29, status=1, ipAttribution=湖南省), GetPortalCommentsPageByObjectIdResponse(id=952359, encodeId=641c9523591a, content=已转发给临床医生, beContent=null, objectType=guider, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210330/89ac79da9e2b46c49dd38698f891938b/15793a72df234d0090cbd82601754957.jpg, createdBy=a3f15387118, createdName=ms5000002143624482, createdTime=Tue Mar 30 13:13:25 CST 2021, time=2021-03-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=806911, encodeId=871580691193, content=有用, beContent=null, objectType=guider, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=66422891930, createdName=1023463763, createdTime=Sat Aug 08 11:18:37 CST 2020, time=2020-08-08, status=1, ipAttribution=)]
    2020-08-08 1023463763

    有用

    0