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家族性高胆固醇血症筛查与诊治中国专家共识

2018-02-28 中华医学会心血管病学分会 中华心血管病杂志,2018,46(2) :99-103.

家族性高胆固醇血症

经典的家族性高胆固醇血症（familial hypercholesterolemia，FH）是一种常染色体（共）显性遗传病，其主要临床表现为血清低密度脂蛋白胆固醇（low density lipoprotein-cholesterol，LDL-C）水平明显升高，以及皮肤/腱黄色瘤。FH患者早发动脉硬化性心血管疾病风险明显增高，而早期筛查和尽早接受药物治疗可改善FH患者的存活率。目前，FH已受到国际

中文标题：

家族性高胆固醇血症筛查与诊治中国专家共识

发布机构：

中华医学会心血管病学分会

发布日期：

2018-02-28

简要介绍：

经典的家族性高胆固醇血症（familial hypercholesterolemia，FH）是一种常染色体（共）显性遗传病，其主要临床表现为血清低密度脂蛋白胆固醇（low density lipoprotein-cholesterol，LDL-C）水平明显升高，以及皮肤/腱黄色瘤。FH患者早发动脉硬化性心血管疾病风险明显增高，而早期筛查和尽早接受药物治疗可改善FH患者的存活率。目前，FH已受到国际社会广泛关注，并相继发布了相关诊断和治疗专家共识或指南，但FH诊断率和治疗率仍严重不足。根据中国患者血脂异常特点，参考国内外临床研究证据和相关指南共识，中华医学会心血管病学分会动脉粥样硬化及冠心病学组、中华心血管病杂志编辑委员会组织制定本共识，旨在提高我国临床医生发现FH患者的能力，促进FH的早期诊断和治疗，规范FH的临床管理。

 

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评论区 (6)
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  1. [GetPortalCommentsPageByObjectIdResponse(id=1179325, encodeId=544811e9325a7, content=很好的内容，学习了, beContent=null, objectType=guider, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=01af1957237, createdName=1e129e46m43(暂无匿称), createdTime=Fri Dec 31 15:16:36 CST 2021, time=2021-12-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=969712, encodeId=d8a9969e122a, content=学习学习, beContent=null, objectType=guider, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ef2c1960942, createdName=1e1366a1m07(暂无匿称), createdTime=Sun May 30 23:23:50 CST 2021, time=2021-05-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=969711, encodeId=702e969e11d2, content=需要好好学习, beContent=null, objectType=guider, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ef2c1960942, createdName=1e1366a1m07(暂无匿称), createdTime=Sun May 30 23:23:44 CST 2021, time=2021-05-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=806976, encodeId=c9ae8069e65d, content=继续学习, beContent=null, objectType=guider, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=568f2273884, createdName=瓜虫, createdTime=Sat Aug 08 19:16:07 CST 2020, time=2020-08-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=293747, encodeId=1dec293e4785, content=学习了.不错耶, beContent=null, objectType=guider, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3b2c1627329, createdName=owlhealth, createdTime=Wed Mar 07 07:07:22 CST 2018, time=2018-03-07, status=1, ipAttribution=)]
    2021-12-31 1e129e46m43(暂无匿称)

    很好的内容，学习了

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=1179325, encodeId=544811e9325a7, content=很好的内容，学习了, beContent=null, objectType=guider, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=01af1957237, createdName=1e129e46m43(暂无匿称), createdTime=Fri Dec 31 15:16:36 CST 2021, time=2021-12-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=969712, encodeId=d8a9969e122a, content=学习学习, beContent=null, objectType=guider, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ef2c1960942, createdName=1e1366a1m07(暂无匿称), createdTime=Sun May 30 23:23:50 CST 2021, time=2021-05-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=969711, encodeId=702e969e11d2, content=需要好好学习, beContent=null, objectType=guider, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ef2c1960942, createdName=1e1366a1m07(暂无匿称), createdTime=Sun May 30 23:23:44 CST 2021, time=2021-05-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=806976, encodeId=c9ae8069e65d, content=继续学习, beContent=null, objectType=guider, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=568f2273884, createdName=瓜虫, createdTime=Sat Aug 08 19:16:07 CST 2020, time=2020-08-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=293747, encodeId=1dec293e4785, content=学习了.不错耶, beContent=null, objectType=guider, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3b2c1627329, createdName=owlhealth, createdTime=Wed Mar 07 07:07:22 CST 2018, time=2018-03-07, status=1, ipAttribution=)]
    2021-05-30 1e1366a1m07(暂无匿称)

    学习学习

    0

  3. [GetPortalCommentsPageByObjectIdResponse(id=1179325, encodeId=544811e9325a7, content=很好的内容，学习了, beContent=null, objectType=guider, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=01af1957237, createdName=1e129e46m43(暂无匿称), createdTime=Fri Dec 31 15:16:36 CST 2021, time=2021-12-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=969712, encodeId=d8a9969e122a, content=学习学习, beContent=null, objectType=guider, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ef2c1960942, createdName=1e1366a1m07(暂无匿称), createdTime=Sun May 30 23:23:50 CST 2021, time=2021-05-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=969711, encodeId=702e969e11d2, content=需要好好学习, beContent=null, objectType=guider, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ef2c1960942, createdName=1e1366a1m07(暂无匿称), createdTime=Sun May 30 23:23:44 CST 2021, time=2021-05-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=806976, encodeId=c9ae8069e65d, content=继续学习, beContent=null, objectType=guider, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=568f2273884, createdName=瓜虫, createdTime=Sat Aug 08 19:16:07 CST 2020, time=2020-08-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=293747, encodeId=1dec293e4785, content=学习了.不错耶, beContent=null, objectType=guider, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3b2c1627329, createdName=owlhealth, createdTime=Wed Mar 07 07:07:22 CST 2018, time=2018-03-07, status=1, ipAttribution=)]
    2021-05-30 1e1366a1m07(暂无匿称)

    需要好好学习

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=1179325, encodeId=544811e9325a7, content=很好的内容，学习了, beContent=null, objectType=guider, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=01af1957237, createdName=1e129e46m43(暂无匿称), createdTime=Fri Dec 31 15:16:36 CST 2021, time=2021-12-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=969712, encodeId=d8a9969e122a, content=学习学习, beContent=null, objectType=guider, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ef2c1960942, createdName=1e1366a1m07(暂无匿称), createdTime=Sun May 30 23:23:50 CST 2021, time=2021-05-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=969711, encodeId=702e969e11d2, content=需要好好学习, beContent=null, objectType=guider, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ef2c1960942, createdName=1e1366a1m07(暂无匿称), createdTime=Sun May 30 23:23:44 CST 2021, time=2021-05-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=806976, encodeId=c9ae8069e65d, content=继续学习, beContent=null, objectType=guider, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=568f2273884, createdName=瓜虫, createdTime=Sat Aug 08 19:16:07 CST 2020, time=2020-08-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=293747, encodeId=1dec293e4785, content=学习了.不错耶, beContent=null, objectType=guider, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3b2c1627329, createdName=owlhealth, createdTime=Wed Mar 07 07:07:22 CST 2018, time=2018-03-07, status=1, ipAttribution=)]
    2020-08-08 瓜虫

    继续学习

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=1179325, encodeId=544811e9325a7, content=很好的内容，学习了, beContent=null, objectType=guider, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=01af1957237, createdName=1e129e46m43(暂无匿称), createdTime=Fri Dec 31 15:16:36 CST 2021, time=2021-12-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=969712, encodeId=d8a9969e122a, content=学习学习, beContent=null, objectType=guider, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ef2c1960942, createdName=1e1366a1m07(暂无匿称), createdTime=Sun May 30 23:23:50 CST 2021, time=2021-05-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=969711, encodeId=702e969e11d2, content=需要好好学习, beContent=null, objectType=guider, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ef2c1960942, createdName=1e1366a1m07(暂无匿称), createdTime=Sun May 30 23:23:44 CST 2021, time=2021-05-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=806976, encodeId=c9ae8069e65d, content=继续学习, beContent=null, objectType=guider, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=568f2273884, createdName=瓜虫, createdTime=Sat Aug 08 19:16:07 CST 2020, time=2020-08-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=293747, encodeId=1dec293e4785, content=学习了.不错耶, beContent=null, objectType=guider, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3b2c1627329, createdName=owlhealth, createdTime=Wed Mar 07 07:07:22 CST 2018, time=2018-03-07, status=1, ipAttribution=)]
    2018-03-07 owlhealth

    学习了.不错耶

    0

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