甲氨蝶呤治疗银屑病应用专家共识

2022-02-05 中华医学会皮肤性病学分会银屑病专业委员会临床皮肤科杂志

甲氨蝶呤(MTX)是一种免疫抑制剂,最初用于恶性肿瘤的治疗,目前在许多自身免疫性疾病和炎症性皮肤病的治疗中也占有重要地位。近年来,来自高质量随机双盲试验(RCT)的大量数据进一步证实MTX在银屑病治疗

中文标题：

甲氨蝶呤治疗银屑病应用专家共识

发布机构：

中华医学会皮肤性病学分会银屑病专业委员会

发布日期：

2022-02-05

简要介绍：

甲氨蝶呤(MTX)是一种免疫抑制剂,最初用于恶性肿瘤的治疗,目前在许多自身免疫性疾病和炎症性皮肤病的治疗中也占有重要地位。近年来,来自高质量随机双盲试验(RCT)的大量数据进一步证实MTX在银屑病治疗中的疗效以及安全性。MTX的毒副作用也逐步明确,在密切监测下,可以安全地应用于银屑病及其他皮肤疾病的治疗。尽管目前有大量的生物制剂及小分子靶向药物上市,但MTX作为治疗银屑病的传统药物,对于国内广大银屑病患者治疗依然有不可替代的作用。该共识的总体目标是对MTX在银屑病治疗中的应用研究现状、用药前评估、常规给药方法、不良反应、毒副作用评估和处理等方面进行介绍与规范,为MTX在中国银屑病患者中有效及安全地应用提供建议。

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2022-09-19 小小医者

中国大剂量#甲氨蝶呤##循证用药#指南，虽然甲氨蝶呤是老药，但是在众多疾病中均广泛应用，包括#银屑病#等#免疫相关性皮肤病#、#类风湿性关节炎#、#幼年特发性关节炎#、#恶性肿瘤#，算是经典的老药

122 0
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2022-03-07 zhengguang50

非常感谢

41 0
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2022-02-25 ms9000000080461052

_学了

56 0

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