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绝经前和绝经后妇女补充脱氢表雄酮（DHEA）-波兰更年期和更年期协会专家小组的立场声明

2020-10-04 波兰更年期和更年期协会（Polish Menopause and Andropause Society） Ginekol Pol . 2020;91(9):554-562. doi: 10.5603/GP.2020.0091

绝经期妇女

脱氢表雄酮（DHEA）的浓度会随着年龄的增长而降低，因此，DHEA被认为是一种可减少与衰老相关的症状的激素，因此DHEA在绝经前和绝经后妇女中的用处以及激素治疗的选择受到了广泛的关注。 DHEA在绝经

中文标题：

绝经前和绝经后妇女补充脱氢表雄酮（DHEA）-波兰更年期和更年期协会专家小组的立场声明

英文标题：

Supplementation of dehydroepiandrosterone (DHEA) in pre- and postmenopausal women - position statement of expert panel of Polish Menopause and Andropause Society

发布机构：

波兰更年期和更年期协会（Polish Menopause and Andropause Society）

发布日期：

2020-10-04

简要介绍：

脱氢表雄酮（DHEA）的浓度会随着年龄的增长而降低，因此，DHEA被认为是一种可减少与衰老相关的症状的激素，因此DHEA在绝经前和绝经后妇女中的用处以及激素治疗的选择受到了广泛的关注。 DHEA在绝经前女性中的有效性尚不清楚，而在绝经后女性中雌激素缺乏并存的女性尚存争议。尽管进行了多年的研究，但DHEA的使用仍存在争议，尤其是在其有效性方面。本文的目的是通过性活动，认知和幸福感的评估方法来评估DHEA对绝经前和绝经后妇女代谢参数，骨矿物质密度，胰岛素抵抗以及DHEA治疗潜力的特异性作用。本文的摘要是波兰更年期和更年期协会专家组关于补充脱氢表雄酮对妇女的功效和安全性的立场声明。我们得出的结论是，目前可用的临床试验和荟萃分析表明，DHEA补充剂对患有肾上腺功能不全且长期接受外源糖皮质激素，骨密度低和/或骨质疏松的绝经后妇女，性障碍和性欲低下的绝经前妇女有效，以及因更年期或更年期泌尿生殖系统综合症而导致的阴道阴道萎缩的女性。目前可用的临床试验还表明，DHEA补充剂可能对患有性欲减退的绝经后妇女，卵巢储备减少的不育妇女，患有抑郁和焦虑症的妇女以及肥胖和胰岛素抵抗的妇女有效。没有严重不良反应的报道。

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    2021-04-07 湘雅科教

    受益匪浅！好文章。

    0

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    2021-03-06 128fc9cam76暂无昵称

    丶买用

    0

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    2020-12-31 oo902

    脱氢表雄酮（DHEA）

    0

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    2020-12-17 1484686em90暂无昵称

    全英文的

    0

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    2020-12-04 ms6000001542812935

    学习

    0