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Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1908 2
1911 2
1912 2
1913 1
1914 1
1915 2
1919 1
1921 3
1922 3
1923 2
1924 4
1926 1
1927 3
1928 1
1929 1
1930 3
1931 2
1932 1
1933 5
1935 2
1936 2
1937 4
1938 5
1939 5
1940 3
1941 3
1942 3
1943 4
1944 8
1945 740
1946 2114
1947 2505
1948 2731
1949 2423
1950 3690
1951 4194
1952 4093
1953 4402
1954 4593
1955 4949
1956 4729
1957 4692
1958 4425
1959 4558
1960 4810
1961 5378
1962 6031
1963 8997
1964 12133
1965 10247
1966 10251
1967 13254
1968 16461
1969 18659
1970 19188
1971 22115
1972 24101
1973 25938
1974 28074
1975 27231
1976 26539
1977 27365
1978 27676
1979 29365
1980 30846
1981 31520
1982 33748
1983 35743
1984 39034
1985 42573
1986 44654
1987 46762
1988 50507
1989 55238
1990 58720
1991 61721
1992 64386
1993 66400
1994 69995
1995 72945
1996 74344
1997 76598
1998 79008
1999 82448
2000 87819
2001 92123
2002 96002
2003 101909
2004 108027
2005 117941
2006 123878
2007 130019
2008 135760
2009 141128
2010 150123
2011 159546
2012 168077
2013 171936
2014 173865
2015 176753
2016 173281
2017 173420
2018 174499
2019 179712
2020 187278
2021 187181
2022 178952
2023 151278
2024 46693

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4,710,986 results

Results by year

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Page 1
Predicting drug disposition via application of BCS: transport/absorption/ elimination interplay and development of a biopharmaceutics drug disposition classification system.
Wu CY, Benet LZ. Wu CY, et al. Pharm Res. 2005 Jan;22(1):11-23. doi: 10.1007/s11095-004-9004-4. Pharm Res. 2005. PMID: 15771225 Review.
The Biopharmaceutics Classification System (BCS) was developed to allow prediction of in vivo pharmacokinetic performance of drug products from measurements of permeability (determined as the extent of oral absorption) and solubility. ...These predictions are suppor …
The Biopharmaceutics Classification System (BCS) was developed to allow prediction of in vivo pharmacokinetic performance of drug …
Progress in biopharmaceutical development.
Kesik-Brodacka M. Kesik-Brodacka M. Biotechnol Appl Biochem. 2018 May;65(3):306-322. doi: 10.1002/bab.1617. Epub 2017 Nov 2. Biotechnol Appl Biochem. 2018. PMID: 28972297 Free PMC article. Review.
Their introduction in the European Union and, recently, the Unites States markets will reduce the costs of biopharmaceutical treatment. This review highlights recent progress in the field of biopharmaceutical development and issues concerning the registration of inn …
Their introduction in the European Union and, recently, the Unites States markets will reduce the costs of biopharmaceutical treatmen …
The Biopharmaceutics Classification System (BCS) and the Biopharmaceutics Drug Disposition Classification System (BDDCS): Beyond guidelines.
Charalabidis A, Sfouni M, Bergström C, Macheras P. Charalabidis A, et al. Int J Pharm. 2019 Jul 20;566:264-281. doi: 10.1016/j.ijpharm.2019.05.041. Epub 2019 May 17. Int J Pharm. 2019. PMID: 31108154 Review.
The recent impact of the Biopharmaceutics Classification System (BCS) and the Biopharmaceutics Drug Disposition Classification System (BDDCS) on relevant scientific advancements is discussed. ...Since recent dissolution studies demonstrate that the two mechanisms (d …
The recent impact of the Biopharmaceutics Classification System (BCS) and the Biopharmaceutics Drug Disposition Classification …
Paediatric oral biopharmaceutics: key considerations and current challenges.
Batchelor HK, Fotaki N, Klein S. Batchelor HK, et al. Adv Drug Deliv Rev. 2014 Jun;73:102-26. doi: 10.1016/j.addr.2013.10.006. Epub 2013 Nov 1. Adv Drug Deliv Rev. 2014. PMID: 24189013 Free article. Review.
The complex process of oral drug absorption is influenced by a host of drug and formulation properties as well as their interaction with the gastrointestinal environment in terms of drug solubility, dissolution, permeability and pre-systemic metabolism. For adult dosage forms the …
The complex process of oral drug absorption is influenced by a host of drug and formulation properties as well as their interaction with the …
Current State and Challenges of Physiologically Based Biopharmaceutics Modeling (PBBM) in Oral Drug Product Development.
Wu D, Li M. Wu D, et al. Pharm Res. 2023 Feb;40(2):321-336. doi: 10.1007/s11095-022-03373-0. Epub 2022 Sep 8. Pharm Res. 2023. PMID: 36076007 Review.
Physiologically based biopharmaceutics modeling (PBBM) emphasizes the integration of physicochemical properties of drug substance and formulation characteristics with system physiological parameters to predict the absorption and pharmacokinetics (PK) of a drug product. ... …
Physiologically based biopharmaceutics modeling (PBBM) emphasizes the integration of physicochemical properties of drug substance and …
Overcoming the challenges in administering biopharmaceuticals: formulation and delivery strategies.
Mitragotri S, Burke PA, Langer R. Mitragotri S, et al. Nat Rev Drug Discov. 2014 Sep;13(9):655-72. doi: 10.1038/nrd4363. Epub 2014 Aug 8. Nat Rev Drug Discov. 2014. PMID: 25103255 Free PMC article. Review.
The formulation and delivery of biopharmaceutical drugs, such as monoclonal antibodies and recombinant proteins, poses substantial challenges owing to their large size and susceptibility to degradation. In this Review we highlight recent advances in formulation and deliver …
The formulation and delivery of biopharmaceutical drugs, such as monoclonal antibodies and recombinant proteins, poses substantial ch …
Towards the development of a paediatric biopharmaceutics classification system: Results of a survey of experts.
Batchelor H, Ernest T, Flanagan T, Klein S, Turner R, Fotaki N, Storey D; EuPFI. Batchelor H, et al. Int J Pharm. 2016 Sep 25;511(2):1151-7. doi: 10.1016/j.ijpharm.2016.06.115. Epub 2016 Jun 25. Int J Pharm. 2016. PMID: 27349792 Free article. Review.
The aim of this research survey was to understand current global thinking around the need for and development of a paediatric biopharmaceutics classification system (pBCS) to be used for the development of paediatric medicines and regulatory purposes (e.g. ...A literature …
The aim of this research survey was to understand current global thinking around the need for and development of a paediatric biopharmace …
Gene Therapy.
Thorne B, Takeya R, Vitelli F, Swanson X. Thorne B, et al. Adv Biochem Eng Biotechnol. 2018;165:351-399. doi: 10.1007/10_2016_53. Adv Biochem Eng Biotechnol. 2018. PMID: 28289769 Review.
4,710,986 results
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