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2023 4
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LonP1 Links Mitochondria-ER Interaction to Regulate Heart Function.
Li Y, Huang D, Jia L, Shangguan F, Gong S, Lan L, Song Z, Xu J, Yan C, Chen T, Tan Y, Liu Y, Huang X, Suzuki CK, Yang Z, Yang G, Lu B. Li Y, et al. Research (Wash D C). 2023 Jun 16;6:0175. doi: 10.34133/research.0175. eCollection 2023. Research (Wash D C). 2023. PMID: 37333972 Free PMC article.
Hepatic HDAC3 Regulates Systemic Iron Homeostasis and Ferroptosis via the Hippo Signaling Pathway.
Meng H, Yu Y, Xie E, Wu Q, Yin X, Zhao B, Min J, Wang F. Meng H, et al. Research (Wash D C). 2023 Nov 30;6:0281. doi: 10.34133/research.0281. eCollection 2023. Research (Wash D C). 2023. PMID: 38034086 Free PMC article.
Here, the putative role of hepatic HDACs in regulating iron metabolism and ferroptosis was investigated using genetic mouse models. Mice lacking Hdac3 expression in the liver (Hdac3-LKO mice) have significantly reduced hepatic Hamp mRNA (encoding the peptide hormone hepcid …
Here, the putative role of hepatic HDACs in regulating iron metabolism and ferroptosis was investigated using genetic mouse models. M …
Transcriptomic and Macroscopic Architectures of Multimodal Covariance Network Reveal Molecular-Structural-Functional Co-alterations.
Jiang L, Peng Y, He R, Yang Q, Yi C, Li Y, Zhu B, Si Y, Zhang T, Biswal BB, Yao D, Xiong L, Li F, Xu P. Jiang L, et al. Research (Wash D C). 2023 Jun 8;6:0171. doi: 10.34133/research.0171. eCollection 2023. Research (Wash D C). 2023. PMID: 37303601 Free PMC article.
Collectively, these findings confirmed the correlations of MCN-related differences with brain-wide gene expression patterns, which captured genetically validated structural-functional differences at the cellular level in specific cognitive processes and psychiatric patient …
Collectively, these findings confirmed the correlations of MCN-related differences with brain-wide gene expression patterns, which captured …
SARS-CoV-2 Epitopes following Infection and Vaccination Overlap Known Neutralizing Antibody Sites.
Yang L, Liang T, Pierson LM, Wang H, Fletcher JK, Wang S, Bao D, Zhang L, Huang Z, Zheng W, Zhang X, Park H, Li Y, Robinson JE, Feehan AK, Lyon CJ, Cao J, Morici LA, Li C, Roy CJ, Yu X, Hu T. Yang L, et al. Research (Wash D C). 2022 Jul 9;2022:9769803. doi: 10.34133/2022/9769803. eCollection 2022. Research (Wash D C). 2022. PMID: 35928300 Free PMC article.
Solar-Driven Producing of Value-Added Chemicals with Organic Semiconductor-Bacteria Biohybrid System.
Yu W, Bai H, Zeng Y, Zhao H, Xia S, Huang Y, Lv F, Wang S. Yu W, et al. Research (Wash D C). 2022 Mar 23;2022:9834093. doi: 10.34133/2022/9834093. eCollection 2022. Research (Wash D C). 2022. PMID: 35402922 Free PMC article.
A new ternary cooperative biohybrid system, namely bacterial factory, was constructed by self-assembling of enzyme-modified light-harvesting donor-acceptor conjugated polymer nanoparticles (D-A CPNs) and genetically engineered Escherichia coli (E. coli). The D-A CPNs coati …
A new ternary cooperative biohybrid system, namely bacterial factory, was constructed by self-assembling of enzyme-modified light-harvesting …
Accurate Identification of DNA Replication Origin by Fusing Epigenomics and Chromatin Interaction Information.
Dao FY, Lv H, Fullwood MJ, Lin H. Dao FY, et al. Research (Wash D C). 2022 Oct 29;2022:9780293. doi: 10.34133/2022/9780293. eCollection 2022. Research (Wash D C). 2022. PMID: 36405252 Free PMC article.
DNA replication initiation is a complex process involving various genetic and epigenomic signatures. The correct identification of replication origins (ORIs) could provide important clues for the study of a variety of diseases caused by replication. ...
DNA replication initiation is a complex process involving various genetic and epigenomic signatures. The correct identification of re …
SH2B1 Tunes Hippocampal ERK Signaling to Influence Fluid Intelligence in Humans and Mice.
Du X, Yan Y, Yu J, Zhu T, Huang CC, Zhang L, Shan X, Li R, Dai Y, Lv H, Zhang XY, Feng J, Li WG, Luo Q, Li F. Du X, et al. Research (Wash D C). 2023 Nov 14;6:0269. doi: 10.34133/research.0269. eCollection 2023. Research (Wash D C). 2023. PMID: 38434247 Free PMC article.
Our results revealed novel common genetic loci (SH2B1, TUFM, ATP2A1, and FOXO3) underlying the association between fluid intelligence and body metabolism. ...Single-cell genetic profiling of Sh2B1-regulated molecular pathways revealed that Sh2b1 deletion resu …
Our results revealed novel common genetic loci (SH2B1, TUFM, ATP2A1, and FOXO3) underlying the association between fluid intelligence …
High-Content Screening and Analysis of Stem Cell-Derived Neural Interfaces Using a Combinatorial Nanotechnology and Machine Learning Approach.
Yang L, Conley BM, Yoon J, Rathnam C, Pongkulapa T, Conklin B, Hou Y, Lee KB. Yang L, et al. Research (Wash D C). 2022 Sep 14;2022:9784273. doi: 10.34133/2022/9784273. eCollection 2022. Research (Wash D C). 2022. PMID: 36204248 Free PMC article.
A systematic investigation of stem cell-derived neural interfaces can facilitate the discovery of the molecular mechanisms behind cell behavior in neurological disorders and accelerate the development of stem cell-based therapies. ...Furthermore, by applying a machine lear …
A systematic investigation of stem cell-derived neural interfaces can facilitate the discovery of the molecular mechanisms behind cel …
12 results