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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1849 1
1851 2
1853 2
1854 1
1858 2
1865 1
1869 2
1870 2
1873 1
1875 1
1876 1
1877 2
1879 5
1880 1
1881 8
1882 3
1883 1
1884 5
1885 5
1886 1
1887 4
1888 5
1889 6
1890 3
1891 4
1892 15
1893 21
1894 6
1895 15
1896 8
1897 15
1898 9
1899 9
1900 9
1901 14
1902 13
1903 19
1904 10
1905 14
1906 3
1907 15
1908 19
1909 16
1910 7
1911 26
1912 23
1913 23
1914 23
1915 28
1916 37
1917 22
1918 20
1919 34
1920 28
1921 30
1922 33
1923 28
1924 48
1925 46
1926 51
1927 53
1928 65
1929 47
1930 38
1931 60
1932 50
1933 61
1934 70
1935 92
1936 95
1937 81
1938 90
1939 83
1940 92
1941 82
1942 69
1943 55
1944 93
1945 1158
1946 3101
1947 3634
1948 3972
1949 3382
1950 5269
1951 5920
1952 5933
1953 6812
1954 7211
1955 7321
1956 6797
1957 6886
1958 6555
1959 6866
1960 7354
1961 8190
1962 9096
1963 13871
1964 19713
1965 16769
1966 15432
1967 20255
1968 24564
1969 26859
1970 27552
1971 31395
1972 33367
1973 34341
1974 36978
1975 37286
1976 36741
1977 37070
1978 37324
1979 39728
1980 41226
1981 41827
1982 44378
1983 47131
1984 50812
1985 54696
1986 57307
1987 62592
1988 70751
1989 77348
1990 82797
1991 86724
1992 90677
1993 93497
1994 98230
1995 101382
1996 104484
1997 107705
1998 112919
1999 118310
2000 128143
2001 136325
2002 143012
2003 153424
2004 165175
2005 181056
2006 194860
2007 207203
2008 217868
2009 227930
2010 244316
2011 260789
2012 275121
2013 287292
2014 309697
2015 326445
2016 331567
2017 335790
2018 344469
2019 358440
2020 386156
2021 404754
2022 391254
2023 356637
2024 97766
2025 1

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7,894,349 results

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Biological therapy management from the initial selection of biologics to switching between biologics in severe asthma.
Yılmaz İ, Paçacı Çetin G, Arslan B, Şeker S, Bozkurt Yılmaz HE, Aktaş Yapıcı E, Köylüce S, Açar E. Yılmaz İ, et al. Tuberk Toraks. 2023 Mar;71(1):75-93. doi: 10.5578/tt.20239910. Tuberk Toraks. 2023. PMID: 36912412 Free PMC article. Review.
The aim of this review is to elaborate the management of biologic therapy from initial selection to switching biologics in severe asthma. ...Therefore, discontinuation of biologics may be a viable strategy in a particular patient group. Clinicians should make …
The aim of this review is to elaborate the management of biologic therapy from initial selection to switching biologics in sev …
Efficacy and safety of biological agents for pemphigoid: a systematic review and meta-analysis.
Lin Z, Zhao Y, Li F, Li J, Huang X. Lin Z, et al. Int J Dermatol. 2023 Aug;62(8):1000-1008. doi: 10.1111/ijd.16678. Epub 2023 May 22. Int J Dermatol. 2023. PMID: 37212599 Review.
Biologic agents (also termed biologics) have become an important adjuvant-targeted treatment option in autoimmune blistering disease. We evaluated the efficacy and safety of newly licensed biologics for the management of pemphigoid using a meta-analysis. PubM
Biologic agents (also termed biologics) have become an important adjuvant-targeted treatment option in autoimmune blistering d
Regulatory aspects of biological medicines in Bosnia and Herzegovina.
Tubić B, Jungić S. Tubić B, et al. Bosn J Basic Med Sci. 2022 Jul 29;22(4):511-522. doi: 10.17305/bjbms.2021.6910. Bosn J Basic Med Sci. 2022. PMID: 35460398 Free PMC article. Review.
The use of the biological medicines, also called "biologics," has contributed to the progress of the treatment of many chronic diseases, such as cancer, rheumatoid arthritis, Crohn's disease, multiple sclerosis, and psoriasis. ...A biosimilar medicine, also called " …
The use of the biological medicines, also called "biologics," has contributed to the progress of the treatment of many chronic …
Challenges in the Development of Biological Approaches for the Treatment of Degenerative Disc Disease.
Goldberg JL, Garton A, Singh S, Kirnaz S, Sommer F, Carnevale JA, Atalay B, Medary B, McGrath LB Jr, Härtl R. Goldberg JL, et al. World Neurosurg. 2022 Jan;157:274-281. doi: 10.1016/j.wneu.2021.09.067. World Neurosurg. 2022. PMID: 34929785 Review.
In addition, the study of the spine and intervertebral disc in animal models is difficult to translate to humans, hindering the utility of preclinical research. Biological treatments are subject to the complex biomechanical environment in which native discs degenerate. ...
In addition, the study of the spine and intervertebral disc in animal models is difficult to translate to humans, hindering the utility of p …
Biologics for severe asthma-Which, when and why?
Shah PA, Brightling C. Shah PA, et al. Respirology. 2023 Aug;28(8):709-721. doi: 10.1111/resp.14520. Epub 2023 May 24. Respirology. 2023. PMID: 37222237 Review.
The goal of asthma management is disease control by reducing symptoms and exacerbations and reducing corticosteroid-related morbidity. The era of biologics has revolutionized the management of severe asthma. Biologics have changed our expectations for severe asthma, …
The goal of asthma management is disease control by reducing symptoms and exacerbations and reducing corticosteroid-related morbidity. The e …
Biological and clinical implications of herbal medicine and natural products for the treatment of inflammatory bowel disease.
Guo BJ, Bian ZX, Qiu HC, Wang YT, Wang Y. Guo BJ, et al. Ann N Y Acad Sci. 2017 Aug;1401(1):37-48. doi: 10.1111/nyas.13414. Ann N Y Acad Sci. 2017. PMID: 28891095 Review.
Inflammatory bowel disease (IBD) is a group of chronic inflammatory disorders that includes Crohn's disease (CD) and ulcerative colitis (UC). Homeostasis of various regulatory factors involved with intestinal immunity is disrupted in IBD, including the intestinal epithelia …
Inflammatory bowel disease (IBD) is a group of chronic inflammatory disorders that includes Crohn's disease (CD) and ulcerative colitis (UC) …
Biologics for severe asthma: The real-world evidence, effectiveness of switching, and prediction factors for the efficacy.
Nagase H, Suzukawa M, Oishi K, Matsunaga K. Nagase H, et al. Allergol Int. 2023 Jan;72(1):11-23. doi: 10.1016/j.alit.2022.11.008. Epub 2022 Dec 19. Allergol Int. 2023. PMID: 36543689 Free article. Review.
Biologics have been a key component of severe asthma treatment, and there are currently biologics available that target IgE, IL-5, IL-4/IL-13, and TSLP. ...Additionally, since there are now multiple biologic options and overlaps in eligibility for biologic
Biologics have been a key component of severe asthma treatment, and there are currently biologics available that target IgE, I
Biologic and Small-Molecule Therapies for Moderate-to-Severe Psoriasis: Focus on Psoriasis Comorbidities.
Jiang Y, Chen Y, Yu Q, Shi Y. Jiang Y, et al. BioDrugs. 2023 Jan;37(1):35-55. doi: 10.1007/s40259-022-00569-z. Epub 2023 Jan 2. BioDrugs. 2023. PMID: 36592323 Free PMC article. Review.
Data from clinical trials and studies on the safety and efficacy of biologics and small-molecule inhibitors provide important information for the personalized care and treatment for patients with psoriasis. ...Apremilast may induce weight loss as an adverse effect, present …
Data from clinical trials and studies on the safety and efficacy of biologics and small-molecule inhibitors provide important informa …
Biological targets and mechanisms of action of natural products from marine cyanobacteria.
Salvador-Reyes LA, Luesch H. Salvador-Reyes LA, et al. Nat Prod Rep. 2015 Mar;32(3):478-503. doi: 10.1039/c4np00104d. Nat Prod Rep. 2015. PMID: 25571978 Free PMC article. Review.
These compounds are presumably optimized by evolution over billions of years to exert high affinity for their intended biological target in the ecologically relevant organism but likely also possess activity in different biological contexts such as human cells. Scre …
These compounds are presumably optimized by evolution over billions of years to exert high affinity for their intended biological tar …
Biologics in the treatment of asthma in children and adolescents.
Bacharier LB, Jackson DJ. Bacharier LB, et al. J Allergy Clin Immunol. 2023 Mar;151(3):581-589. doi: 10.1016/j.jaci.2023.01.002. Epub 2023 Jan 24. J Allergy Clin Immunol. 2023. PMID: 36702649 Review.
Fortunately, more recent research specifically in children has provided an evidence base for biologic use in this age group. Most children with severe asthma demonstrate a type 2 inflammatory phenotype, the primary target of currently approved biologics. ...Safety p …
Fortunately, more recent research specifically in children has provided an evidence base for biologic use in this age group. Most chi …
7,894,349 results
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