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Disparities, aging and childhood cancer
A study reports that survivors of childhood cancer age faster than healthy controls and have increased risk of frailty and death; however, heterogeneity in outcomes was present, indicating inequities in risk. Knowledge about aging in high-risk groups holds the potential to identify interventions to improve survivorship outcomes.
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Lipids as mediators of cancer progression and metastasis
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Sarcoma microenvironment cell states and ecosystems are associated with prognosis and predict response to immunotherapy
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Cytidine deaminases APOBEC3C and APOBEC3D promote DNA replication stress resistance in pancreatic cancer cells
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The pleiotropic functions of reactive oxygen species in cancer