期刊: NUCLEIC ACIDS RESEARCH, 2023; 51 (17)
Bacterial conjugation was first described by Lederberg and Tatum in the 1940s following the discovery of the F plasmid. During conjugation a plasmid i......
期刊: NUCLEIC ACIDS RESEARCH, 2023; 51 (17)
MSL2, the DNA-binding subunit of the Drosophila dosage compensation complex, cooperates with the ubiquitous protein CLAMP to bind MSL recognition elem......
期刊: NUCLEIC ACIDS RESEARCH, 2023; ()
Single-stranded RNA folds into a variety of secondary and higher-order structures. Distributions and dynamics of multiple RNA conformations are respon......
期刊: NUCLEIC ACIDS RESEARCH, 2023; ()
Pathway analysis, including nontopology-based (non-TB) and topology-based (TB) methods, is widely used to interpret the biological phenomena underlyin......
期刊: NUCLEIC ACIDS RESEARCH, 2023; 51 (D1)
AI-driven protein structure prediction, most notably AlphaFold2 (AF2) opens new frontiers for almost all fields of structural biology. As traditional ......
期刊: NUCLEIC ACIDS RESEARCH, 2023; 51 (D1)
HGTree is a database that provides horizontal gene transfer (HGT) event information on 2472 prokaryote genomes using the tree-reconciliation method. H......
期刊: NUCLEIC ACIDS RESEARCH, 2023; 51 (D1)
The identification of unknown chemicals has emerged as a significant issue in untargeted metabolome analysis owing to the limited availability of puri......
期刊: NUCLEIC ACIDS RESEARCH, 2023; 51 (D1)
Gene co-expression analysis has emerged as a powerful method to provide insights into gene function and regulation. The rapid growth of publicly avail......
期刊: NUCLEIC ACIDS RESEARCH, 2023; 51 (4)
The molecular heterogeneity of cancer cells contributes to the often partial response to targeted therapies and relapse of disease due to the escape o......
期刊: NUCLEIC ACIDS RESEARCH, 2023; 51 (7)
Homology-directed recombination (HDR) between donor constructs and acceptor genomic sequences cleaved by programmable nucleases, permits installing la......
期刊: NUCLEIC ACIDS RESEARCH, 2023; 51 (10)
The marine thermophilic archaeon Nanoarchaeum equitans possesses a monomeric primase encompassing the conserved domains of the small catalytic and the......
期刊: NUCLEIC ACIDS RESEARCH, 2023; 51 (W1)
Recent advances have shown that some biologically active non-coding RNAs (ncRNAs) are actually translated into polypeptides that have a physiological ......
期刊: NUCLEIC ACIDS RESEARCH, 2023; 51 (12)
Coordination of bacterial stress response mechanisms is critical for long-term survival in harsh environments for successful host infection. The gener......