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Microbiota associations with inflammatory pathways in asthma

期刊: CLINICAL AND EXPERIMENTAL ALLERGY, 2022; 52 (5)

Background The airway microbiota plays an important role in asthma pathophysiology. However, the relationship between the airway microbiota and asthma......

JIF:3.261

Revisiting Asian chronic rhinosinusitis in the era of type 2 biologics

期刊: CLINICAL AND EXPERIMENTAL ALLERGY, 2022; 52 (2)

Chronic rhinosinusitis (CRS) is a highly heterogeneous disorder exhibiting considerable epidemiological, clinical and immunopathological variations ac......

JIF:3.261

Hypersensitivity may be involved in severe COVID-19

期刊: CLINICAL AND EXPERIMENTAL ALLERGY, 2022; 52 (2)

Background Deaths attributed to Coronavirus Disease 2019 (COVID-19) are mainly due to severe hypoxemic respiratory failure. Although the inflammatory ......

JIF:3.261

Substance P-induced lung inflammation in mice is mast cell dependent

期刊: CLINICAL AND EXPERIMENTAL ALLERGY, 2022; 52 (1)

Background Allergic asthma is a common inflammatory lung disease and a major health problem worldwide. Mast cells (MCs) play a key role in the early-s......

JIF:3.261

Anti-IgE effect of small-molecule-compound arctigenin on food allergy in association with a distinct transcriptome profile

期刊: CLINICAL AND EXPERIMENTAL ALLERGY, 2022; 52 (2)

Background Excessive production of IgE plays a major role in the pathology of food allergy. In an attempt to identify anti-IgE natural products, Arcti......

JIF:3.261

Suppression function against environmental dust exposure after Dermatophagoides pteronyssinus immunotherapy is associated with production of specific and cross-reactive immunoglobulin G4

期刊: CLINICAL AND EXPERIMENTAL ALLERGY, 2022; 52 (7)

Background Whether Dermatophagoides pteronyssinus (Der-p) allergen immunotherapy (AIT) can induce Dermatophagoides farina (Der-f)-specific immunoglobu......

JIF:3.261

Heterogeneity of the pharmacologic treatment of allergic rhinitis in Europe based on MIDAS and OTCims platforms

期刊: CLINICAL AND EXPERIMENTAL ALLERGY, 2021; 51 (8)

Background The practice of allergology varies widely between countries, and the costs and sales for the treatment of rhinitis differ depending on prac......

Exogenous factors in the pathogenesis of atopic dermatitis: Irritants and cutaneous infections

期刊: CLINICAL AND EXPERIMENTAL ALLERGY, ; ()

Atopic dermatitis (AD) is a chronic relapsing inflammatory cutaneous disease that is often associated with other atopic symptoms, such as food allergy......

Neutrophilic asthma features increased airway classical monocytes

期刊: CLINICAL AND EXPERIMENTAL ALLERGY, 2021; 51 (2)

Background Monocytes and macrophages are critical innate immune cells of the airways. Despite their differing functions, few clinical studies discrimi......

Exogenous factors in the pathogenesis of atopic dermatitis: Irritants and cutaneous infections

期刊: CLINICAL AND EXPERIMENTAL ALLERGY, 2021; 51 (3)

Atopic dermatitis (AD) is a chronic relapsing inflammatory cutaneous disease that is often associated with other atopic symptoms, such as food allergy......

Relationship of sputum mast cells with clinical and inflammatory characteristics of asthma

期刊: CLINICAL AND EXPERIMENTAL ALLERGY, 2020; 50 (6)

Background Mast cells (MCs) are innate immune cells that regulate atopic and non-atopic inflammation in the airways. MCs play a critical role in the p......

Vitamin A deficiency exacerbates extrinsic atopic dermatitis development by potentiating type 2 helper T cell-type inflammation and mast cell activation

期刊: CLINICAL AND EXPERIMENTAL ALLERGY, 2020; 50 (8)

Background Vitamin A deficiency (VAD) has been hypothesized to play a role in the pathophysiology of atopic dermatitis (AD). Objective We sought to ve......

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