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The Asia-Pacific League of Associations for Rheumatology consensus statements on the management of systemic lupus erythematosus

期刊: LANCET RHEUMATOLOGY, 2021; 3 (7)

Systemic lupus erythematosus (SLE) is prevalent in Asia and carries a variable prognosis among patients across the Asia-Pacific region, which could re......

Factors associated with damage accrual in patients with systemic lupus erythematosus with no clinical or serological disease activity: a multicentre cohort study

期刊: LANCET RHEUMATOLOGY, 2020; 2 (1)

Background Evaluating the contribution of glucocorticoid use to organ damage in systemic lupus erythematosus is confounded by glucocorticoid use in ac......

Risk of hydroxychloroquine alone and in combination with azithromycin in the treatment of rheumatoid arthritis: a multinational, retrospective study

期刊: LANCET RHEUMATOLOGY, 2020; 2 (11)

Background Hydroxychloroquine, a drug commonly used in the treatment of rheumatoid arthritis, has received much negative publicity for adverse events ......

Burden of osteoarthritis in China, 1990-2017: findings from the Global Burden of Disease Study 2017

期刊: LANCET RHEUMATOLOGY, 2020; 2 (3)

Background China has seen a remarkable epidemiological and demographic transition during the past three decades. We aimed to describe the prevalence o......

Safety and efficacy of metformin in systemic lupus erythematosus: a multicentre, randomised, double-blind, placebo-controlled trial

期刊: LANCET RHEUMATOLOGY, 2020; 2 (4)

Background Immunometabolism is involved in the pathogenesis of systemic lupus erythematosus (SLE). The aim of this study was to repurpose metformin, a......

The immunology of COVID-19: is immune modulation an option for treatment?

期刊: LANCET RHEUMATOLOGY, 2020; 2 (7)

In December, 2019, an outbreak of COVID-19 emerged in Wuhan, China and quickly spread globally. As of May 7, 2020, there were 3 672 238 confirmed infe......

COVID-19 in patients with rheumatic disease in Hubei province, China: a multicentre retrospective observational study

期刊: LANCET RHEUMATOLOGY, 2020; 2 (9)

Background In the ongoing COVID-19 pandemic, the susceptibility of patients with rheumatic diseases to COVID-19 remains unclear. We aimed to investiga......

First-in-Human study of JNJ-55920839 in healthy volunteers and patients with systemic lupus erythematosus: a randomised placebo-controlled phase 1 trial

期刊: LANCET RHEUMATOLOGY, 2020; 2 (10)

Background Activation of the type I interferon (IFN) pathway is associated with systemic lupus erythematosus (SLE). We assessed the safety and tolerab......

Prediction models for the risk of total knee replacement: development and validation using data from multicentre cohort studies

期刊: LANCET RHEUMATOLOGY, 2022; 4 (2)

Background Few prognostic prediction models for total knee replacement are available, and the role of radiographic findings in predicting its use rema......

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