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Telomere length is maternally inherited and associated with lipid metabolism in Chinese population

期刊: AGING-US, 2022; 14 (1)

Telomere is a unique DNA-protein complex which covers the ends of chromosomes to avoid end fusion and maintain the stability and integrity of chromoso......

JIF:4.909

A dynamic model to predict long-term outcomes in patients with prolonged disorders of consciousness

期刊: AGING-US, 2022; 14 (2)

Purpose: It is important to predict the prognosis of patients with prolonged disorders of consciousness (DOC). This study established and validated a ......

JIF:4.909

Galectin-9 expression predicts poor prognosis in hepatitis B virus-associated hepatoceluular carcinoma

期刊: AGING-US, 2022; 14 (4)

Objectives: The aim of this study was to explore the expression of Galectin-9 in hepatitis B virus (HBV)associated hepatocellular carcinoma (HCC), eva......

JIF:4.909

Qi Ling decreases paclitaxel resistance in the human prostate cancer by reversing tumor-associated macrophages function

期刊: AGING-US, 2022; 14 (4)

Tumor-associated macrophages (TAMs) are critical immune cells infiltrated into tumor. In present study, we evaluated the effects of Qi Ling (QL), a tr......

JIF:4.909

The association between rs1260326 with the risk of NAFLD and the mediation effect of triglyceride on NAFLD in the elderly Chinese Han population

期刊: AGING-US, 2022; 14 (6)

Background: Accumulated studies have pointed out the striking association between variants in or near APOC3, GCKR, PNPLA3, and nonalcoholic fatty live......

JIF:4.909

SNP rs322931 (C > T) in miR-181b and rs7158663 (G > A) in MEG3 aggravate the inflammatory response of anal abscess in patients with Crohn's disease

期刊: AGING-US, 2022; 14 (7)

Background: The MEG3/miR-181b signaling has been implicated in the pathogenesis of several diseases including Crohn's disease. This work aimed to stud......

JIF:4.909

Hypoxic pretreatment of adipose-derived stem cell exosomes improved cognition by delivery of circ-Epc1 and shifting microglial M1/M2 polarization in an Alzheimer's disease mice model

期刊: AGING-US, 2022; 14 (7)

Alzheimer's disease (AD) is the most common dementia in the world. Increasing evidence has shown that exosomes from hypoxic pretreated adipose-derived......

JIF:4.909

Clinical outcomes and potential therapies prediction of subgroups based on a ferroptosis-related long non-coding RNA signature for gastric cancer

期刊: AGING-US, 2022; 14 (15)

Background: Gastric cancer (GC) is one of the most aggressive malignant tumors worldwide. Ferroptosis is a kind of iron-dependent cell death, which is......

JIF:4.909

Pyroptosis patterns of colon cancer could aid to estimate prognosis, microenvironment and immunotherapy: evidence from multi-omics analysis

期刊: AGING-US, 2022; 14 (18)

Pyroptosis plays a critical role in the occurrence and development of colon cancer (CC). However, the specific mechanisms of pyroptosis patterns on im......

JIF:4.909

Over-expression of NFYB affects stromal cells reprogramming and predicts worse survival in gastric cancer patients

期刊: AGING-US, 2022; 14 (19)

Gastric cancer (GC) is the fifth most common cancer worldwide and the third most fatal. Cancer-associated fibroblasts (CAFs) play an essential role in......

JIF:4.909

Palmitic acid inhibits vascular smooth muscle cell switch to synthetic phenotype via upregulation of miR-22 expression

期刊: AGING-US, 2022; 14 (19)

Synthetic phenotype switch of vascular smooth muscle cells (VSMCs) has been shown to play key roles in vascular diseases. Mounting evidence has shown ......

JIF:4.909

Starvation-induced long non-coding RNAs are significant for prognosis evaluation of bladder cancer

期刊: AGING-US, 2022; 14 (24)

Background: Starving intratumoral microenvironment prominently alters genic profiles including long non-coding RNAs (lncRNAs), which further regulate ......

JIF:4.909

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