筛选条件 共查询到500条结果
排序方式
Influence of compression kinetics during tableting of fluidized bed-granulated microorganisms on microbiological and physical-mechanical tablet properties

期刊: EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS, 2023; 188 ()

As tablets are convenient to administer to patients, ensure safe dosing and allow cost-effective production on a large scale, they are the favored dos......

Tailoring the release of drugs having different water solubility by hybrid polymer-lipid microparticles with a biphasic structure

期刊: EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS, 2023; 190 ()

The aim of this study is to investigate the potential of hybrid polymer-lipid microparticles with a biphasic structure (b-MPs) as drug delivery system......

Transdermal delivery of mitochondrial-targeted hydrogen sulphide donor, AP39 protects against 6-hydroxydopamine-induced mitochondrial dysfunction

期刊: EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS, 2023; 191 ()

Hydrogen sulphide (H2S) is an important gaseous signalling molecule with emerging roles as a neuroprotectant. The objective of this study was to inves......

Simple preparation of POxylated nanomaterials for cancer chemo-PDT/PTT

期刊: EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS, 2023; 184 ()

Near infrared (NIR) light-responsive nanomaterials hold potential to mediate combinatorial therapies targeting several cancer hallmarks. When irradiat......

Model-based optimization of drug release rate from a size distributed population of biodegradable polymer carriers

期刊: EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS, 2023; 186 ()

In the present study, a comprehensive polymer degradation-drug diffusion model is developed to describe the polymer degradation kinetics and quantify ......

Development of a sustained release implant of benzathine penicillin G for secondary prophylaxis of rheumatic heart disease

期刊: EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS, 2023; 189 ()

Background: Regular intramuscular (i.m.) benzathine penicillin G (BPG) injections have been the cornerstone of rheumatic heart disease (RHD) secondary......

Deep eutectic solvents based on sugars for oral applications

期刊: EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS, 2023; 191 ()

Solubility is a critical parameter in drug formulation to achieve the desired therapeutical concentration. Most drugs are weak acids or bases and, the......

Inorganic nanoparticles in dermopharmaceutical and cosmetic products: Properties, formulation development, toxicity, and regulatory issues

期刊: EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS, 2023; 192 ()

The use of nanotechnology strategies is a current hot topic, and research in this field has been growing significantly in the cosmetics industry. Inor......

PLGA and PEG based porous microparticles as vehicles for pulmonary somatropin delivery

期刊: EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS, 2023; 191 ()

Breakthrough advances in protein therapeutics and sustained release systems continue to fuel innovation in novel, non-invasive polymeric platforms for......

Photo-induced site-specific oxidative fragmentation of IgG1 mediated by iron(III)-containing histidine buffer: Mechanistic studies and excipient effects

期刊: EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS, 2023; 190 ()

Fragmentation may compromise the clinical efficacy and safety profile of monoclonal antibodies (mAbs). We recently reported that Fe(III)-containing hi......

Structured solubility behaviour in fed simulated intestinal fluids

期刊: EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS, 2023; 193 ()

Intestinal drug solubility is a key parameter controlling absorption after the administration of a solid oral dosage form. The ability to measure fed ......

Skin absorption of inorganic nanoparticles and their toxicity: A review

期刊: EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS, 2023; 182 ()

The role of inorganic nanoparticles in our society is increasing every day, from its use in sunscreens to their introduction in analytical laboratorie......

Application of biorelevant in vitro assays for the assessment and optimization of ASD-based formulations for pediatric patients

期刊: EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS, 2023; 185 ()

Amorphous solid dispersions (ASD) have been a successful formulation strategy to overcome the poor aqueous solubility of many novel drugs, but the dev......

共500条页码: 1/34页15条/页