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Differences in clinical characteristics and tumor prognosis between primary and secondary conventional pelvic chondrosarcoma

期刊: BMC CANCER, 2020; 20 (1)

Background Chondrosarcoma (CS) most commonly involves the pelvis. This study aimed to analyze differences in clinical characteristics and prognostic f......

Prediction of prognostic signatures in triple-negative breast cancer based on the differential expression analysis via NanoString nCounter immune panel

期刊: BMC CANCER, 2020; 20 (1)

Background: Triple-Negative Breast Cancer (TNBC) is an aggressive and complex subtype of breast cancer. The current biomarkers used in the context of ......

Various pathways of zoledronic acid against osteoclasts and bone cancer metastasis: a brief review

期刊: BMC CANCER, 2020; 20 (1)

Zoledronic acid (ZA) is one of the most important and effective class of anti-resorptive drug available among bisphosphonate (BP), which could effecti......

Novel nomogram to predict risk of bone metastasis in newly diagnosed thyroid carcinoma: a population-based study

期刊: BMC CANCER, 2020; 20 (1)

BackgroundThe aim of this study was to develop and validate a visual nomogram for predicting the risk of bone metastasis (BM) in newly diagnosed thyro......

High proportion of anergic B cells in the bone marrow defined phenotypically by CD21(-/low)/CD38-expression predicts poor survival in diffuse large B cell lymphoma

期刊: BMC CANCER, 2020; 20 (1)

BackgroundDiffuse large B cell lymphoma (DLBCL) is the commonest lymphoma that is highly aggressive where one-third of the patients relapse despite ef......

The study protocol of the evaluation for the preventive efficacy of the HPV vaccine for persistent HPV16/18 infection in Japanese adult women: the HAKUOH study

期刊: BMC CANCER, 2020; 20 (1)

BackgroundIn general, human papillomavirus (HPV) vaccines have demonstrated efficacy in young women worldwide, but there is limited evidence on the ef......

Anti-tumor efficacy of CKD-516 in combination with radiation in xenograft mouse model of lung squamous cell carcinoma

期刊: BMC CANCER, 2020; 20 (1)

Background: Hypoxic tumors are known to be highly resistant to radiotherapy and cause poor prognosis in non-small cell lung cancer (NSCLC) patients. C......

A clear cancer cell line (150057) derived from human endometrial carcinoma harbors two novel mutations

期刊: BMC CANCER, 2020; 20 (1)

BackgroundCell lines are extremely useful for both basic and clinical research. Thus, establishing endometrial cancer cell lines with malignant histol......

Intraventricular neuroepithelial tumors: surgical outcome, technical considerations and review of literature

期刊: BMC CANCER, 2020; 20 (1)

BackgroundIntraventricular neuroepithelial tumors (IVT) are rare lesions and comprise different pathological entities such as ependymomas, subependymo......

Development and validation of a nomogram to predict overall survival for patients with metastatic renal cell carcinoma

期刊: BMC CANCER, 2020; 20 (1)

BackgroundHeterogeneity of metastatic renal cell carcinoma (RCC) constraints accurate prognosis prediction of the tumor. We therefore aimed at develop......

Identification of ALDH3A2 as a novel prognostic biomarker in gastric adenocarcinoma using integrated bioinformatics analysis

期刊: BMC CANCER, 2020; 20 (1)

BackgroundExtensive research has revealed that genes play a pivotal role in tumor development and growth. However, the underlying involvement of gene ......

The DLC-1 tumor suppressor is involved in regulating immunomodulation of human mesenchymal stromal /stem cells through interacting with the Notch1 protein

期刊: BMC CANCER, 2020; 20 (1)

BackgroundImmunomodulatory activities of human mesenchymal stromal /stem cells (hMSCs) has been widely recognized as the most critical function of hMS......

Retrospective analysis of LNM risk factors and the effect of chemotherapy in early colorectal cancer: A Chinese multicenter study

期刊: BMC CANCER, 2020; 20 (1)

Background Estimating the risk of lymph node metastasis (LNM) is crucial for determining subsequent treatments following curative resection of early c......

Phase II study of sequential S-1 and cyclophosphamide therapy in patients with metastatic breast cancer

期刊: BMC CANCER, 2020; 20 (1)

Background S-1 and cyclophosphamide (CPA) can be given orally, and their combination may have great potential for treating metastatic breast cancer (M......

A nuclear transport-related gene signature combined with IDH mutation and 1p/19q codeletion better predicts the prognosis of glioma patients

期刊: BMC CANCER, 2020; 20 (1)

BackgroundThe nuclear transport system has been proposed to be indispensable for cell proliferation and invasion in cancers. Prognostic biomarkers and......

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