期刊: LIFE SCIENCES, 2021; 276 ()
Aim: To investigate the potential role of IL37 in hepatic ischemia reperfusion injury and its underlying molecular mechanism. Methods: C57BL/6 mouse a......
期刊: LIFE SCIENCES, 2021; 277 ()
Background: Maresin 1 (MaR1) is a pro-resolving lipid mediator that has been reported to have strong regulatory effects on oxidative stress and inflam......
期刊: LIFE SCIENCES, 2021; 278 ()
Aims: Adipocyte-secreted microvesicles (MVs)-derived microRNAs (miRNAs) are relevant to adipogenic and osteogenic differentiation of bone marrow mesen......
期刊: LIFE SCIENCES, 2021; 280 ()
Aims: Silent information regulator 1 (SIRT1) is a NAD+-dependent protein-modifying enzyme involved in regulating gene expression, DNA damage repair, c......
期刊: LIFE SCIENCES, 2021; 280 ()
Aims: Resveratrol pretreatment can decrease ischemic cerebral injury and enhance proliferation of neural stem cells via mediation of Sonic Hedgehog si......
期刊: LIFE SCIENCES, 2021; 282 ()
R-spondins 2 (RSPO2) protein is a member of RSPO family which plays an essential role in stem cell survival, development and tumorigenicity. There has......
期刊: LIFE SCIENCES, 2021; 278 ()
Multidrug resistance gene (MDR1a) and P-glycoprotein (P-gp) play an important role in the development of ulcerative colitis (UC) and influence the the......
期刊: LIFE SCIENCES, 2021; 278 ()
Aims: The expression of antisense lncRNA STXBP5-AS1 and its sense gene STXBP5 were found to be downregulated in glioma by RNA sequencing; however, the......
期刊: LIFE SCIENCES, 2021; 278 ()
Objective: Pancreatic cancer (PC) cells-derived exosomes could mediate angiogenesis of human microvascular endothelial cells (HUVECs) in PC. Consideri......
期刊: LIFE SCIENCES, 2021; 280 ()
Aims: The preclinical evaluation of innovative drugs plays an important role in the new drugs development. As a derivative of pirfenidone (PFD), mefun......
期刊: LIFE SCIENCES, 2021; 271 ()
Aims: Dysfunction of major cells constituting the aortic wall is the pathological basis for AD development. Determining whether non-coding RNAs can in......
期刊: LIFE SCIENCES, 2021; 271 ()
Alzheimer's disease (AD) is the most common cause of dementia and is set to rise in prevalence as the global trends in population aging. The extracell......
期刊: LIFE SCIENCES, 2021; 274 ()
Aims: Fibroblast growth factor 21 (FGF21) has been identified as the master hormonal regulator of energy balance, its elevation is observed in a serie......
期刊: LIFE SCIENCES, 2021; 275 ()
Aims: Defective tight junctions (TJs) can induce intestinal epithelial dysfunction, which participates in various diseases such as irritable bowel syn......
期刊: LIFE SCIENCES, 2021; 277 ()
Objective: MicroRNAs are well-established players in post-transcriptional gene modulation. We aim to explore the role of microRNA-15a-5p (miR-15a-5p)/......