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Peripheral blood helper T cell profiles and their clinical relevance in MOG-IgG-associated and AQP4-IgG-associated disorders and MS

期刊: JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 2020; 91 (2)

Objective To investigate the immunological characteristics and their clinical relevance in anti-myelin oligodendrocyte glycoprotein (MOG)-IgG-associat......

Genetic variants in incident SUDEP cases from a community-based prospective cohort with epilepsy

期刊: JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 2020; 91 (2)

Objective Sudden unexpected death in epilepsy (SUDEP) is a leading cause of epilepsy-related mortality in young adults. It has been suggested that SUD......

Pallidal deep brain stimulation in primary Meige syndrome: clinical outcomes and psychiatric features

期刊: JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 2020; 91 (12)

Objectives To study the efficacy and safety of bilateral globus pallidus internus deep brain stimulation (GPi-DBS) in refractory Meige syndrome (MS) a......

Anti-A beta agents for mild to moderate Alzheimer's disease: systematic review and meta-analysis

期刊: JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 2020; 91 (12)

Objective To assess the efficacy and safety of A beta-targeting agents for mild to moderate Alzheimer's disease Methods The MEDLINE, Embase, Cochrane ......

Brain imaging abnormalities and outcome after acute ischaemic stroke: the ENCHANTED trial

期刊: JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 2020; 91 (12)

Objective To test the hypothesis that imaging signs of 'brain frailty' and acute ischaemia predict clinical outcomes and symptomatic intracranial haem......

Sleep problems and risk of all-cause cognitive decline or dementia: an updated systematic review and meta-analysis

期刊: JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 2020; 91 (3)

Objectives To conduct an updated systematic review and meta-analysis of association between sleep and all-cause cognitive disorders. Methods PubMed an......

Incidence and prevalence of amyotrophic lateral sclerosis in urban China: a national population-based study

期刊: JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 2020; 91 (5)

Objective Amyotrophic lateral sclerosis (ALS) is a severe neurodegenerative disease and information on disease burden of ALS in mainland China was lim......

Clinical prognosis of FLAIR hyperintense arteries in ischaemic stroke patients: a systematic review and meta-analysis

期刊: JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 2020; 91 (5)

Objective We performed a systematic review and meta-analysis to determine the association of fluid-attenuated inversion recovery (FLAIR) hyperintense ......

Pain and the immune system: emerging concepts of IgG-mediated autoimmune pain and immunotherapies

期刊: JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 2020; 91 (2)

The immune system has long been recognised important in pain regulation through inflammatory cytokine modulation of peripheral nociceptive fibres. Rec......

Impact of GBA1 variants on long-term clinical progression and mortality in incident Parkinson's disease

期刊: JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 2020; 91 (7)

Introduction Variants in theGBA1gene have been identified as a common risk factor for Parkinson's disease (PD). In addition to pathogenic mutations (t......

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