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Identification of the Exercise and Time Effects on Human Skeletal Muscle through Bioinformatics Methods

期刊: GENETICS RESEARCH, 2022; 2022 ()

Background. The human body has more than 600 kinds of skeletal muscles, which accounts for about 40% of the whole weight. Most skeletal muscles can ma......

JIF:2.6

Upregulation of Klotho Aggravates Insulin Resistance in Gestational Diabetes Mellitus Trophoblast Cells

期刊: GENETICS RESEARCH, 2022; 2022 ()

Objective. Insulin resistance (IR) plays a key role in gestational diabetes mellitus (GDM) pathogenesis. The antiaging protein klotho has been proven ......

JIF:2.6

Relationship between CYP2C19 Polymorphism and Clopidogrel Resistance in Patients with Coronary Heart Disease and Ischemic Stroke in China

期刊: GENETICS RESEARCH, 2022; 2022 ()

Objective. Clopidogrel is widely used for preventing ischemic complications related to cardiovascular diseases. However, many patients experience clop......

JIF:2.6

Downregulated miR-150-5p in the Tissue of Nasopharyngeal Carcinoma

期刊: GENETICS RESEARCH, 2022; 2022 ()

The clinical significance and potential targets of miR-150-5p have not been elucidated in nasopharyngeal carcinoma (NPC). The pooled analysis based on......

JIF:2.6

Exploration of the Mechanism of Linoleic Acid Metabolism Dysregulation in Metabolic Syndrome

期刊: GENETICS RESEARCH, 2022; 2022 ()

We aimed to explore the mechanism of the linoleic acid metabolism in metabolic syndrome (MetS). RNA-seq data for 16 samples with or without MetS from ......

JIF:2.6

The Underlying Molecular Basis and Mechanisms of Venous Thrombosis in Patients with Osteomyelitis: A Data-Driven Analysis

期刊: GENETICS RESEARCH, 2022; 2022 ()

Objective. Osteomyelitis (OM) is one of the most risky and challenging diseases. Emerging evidence indicates OM is a risk factor for increasing incide......

JIF:2.6

The Protective Effect of Trichosanthes kirilowii Peel Polysaccharide on the Oxidative Damaged HepG2 and HUASMC Cells

期刊: GENETICS RESEARCH, 2022; 2022 ()

Background. Oxidative stress is an important cause of liver disease and atherosclerosis. Natural substances with antioxidant activity are good drugs f......

JIF:2.6

Six MicroRNA Prognostic Models for Overall Survival of Lung Adenocarcinoma

期刊: GENETICS RESEARCH, 2022; 2022 ()

Objective. The purpose of this study is to screen for microRNAs (miRNAs) associated with the prognosis of lung adenocarcinoma (LUAD) and to explore it......

JIF:2.6

Bioinformatics Analysis of miRNAs Targeting TRAF5 in DLBCL Involving in NF-kappa B Signaling Pathway and Affecting the Apoptosis and Signal Transduction

期刊: GENETICS RESEARCH, 2022; 2022 ()

Background. Diffuse large B-cell lymphoma (DLBCL) is an aggressive B-cell lymphoma with high heterogeneity. There is an unmet need to investigate vali......

JIF:2.6

Positive Expression of Retinol-Binding Protein 4 Is Related to the Malignant Clinical Features Leading to Poor Prognosis of Glioblastoma

期刊: GENETICS RESEARCH, 2022; 2022 ()

Backgrounds. Retinol-binding protein 4 (RBP4) is a monomeric-binding protein belonging to the lipocalin protein family, which has been reported to be ......

JIF:2.6

TPX2 Serves as a Cancer Susceptibility Gene and Is Closely Associated with the Poor Prognosis of Endometrial Cancer

期刊: GENETICS RESEARCH, 2022; 2022 ()

Background. Endometrial cancer (EC) is a common tumor of the genital tract that affects the female reproductive system but with only limited treatment......

JIF:2.6

Breast Cancer Prognosis Prediction and Immune Pathway Molecular Analysis Based on Mitochondria-Related Genes

期刊: GENETICS RESEARCH, 2022; 2022 ()

Background. Mitochondria play an important role in breast cancer (BRCA). We aimed to build a prognostic model based on mitochondria-related genes. Met......

JIF:2.6

Effects of Genetic Variants in the Nicotine Metabolism Pathway on Smoking Cessation

期刊: GENETICS RESEARCH, 2022; 2022 ()

Background. We aimed to investigate the associations of various genetic variants in the nicotine metabolism pathway with smoking cessation (SC) in the......

JIF:2.6

Bioinformatics Analysis Identifies TNFRSF1A as a Biomarker of Liver Injury in Sepsis TNFRSF1A is a Biomarker for Septic Liver Injury

期刊: GENETICS RESEARCH, 2022; 2022 ()

Sepsis is a severe disease with high mortality, and liver injury is an independent risk factor for sepsis morbidity and mortality. We analyzed co-diff......

JIF:2.6

Identification of Glucose Metabolism-Related Genes in the Progression from Nonalcoholic Fatty Liver Disease to Hepatocellular Carcinoma

期刊: GENETICS RESEARCH, 2022; 2022 ()

Nonalcoholic fatty liver disease (NAFLD) is a manifestation of hepatic metabolic syndrome that varies in severity. Hepatocellular carcinoma progresses......

JIF:2.6

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