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SplicingFactory-splicing diversity analysis for transcriptome data

期刊: BIOINFORMATICS, 2022; 38 (2)

Motivation: Alternative splicing contributes to the diversity of RNA found in biological samples. Current tools investigating patterns of alternative ......

JIF:7.142

Microbiome Toolbox: methodological approaches to derive and visualize microbiome trajectories

期刊: BIOINFORMATICS, 2023; 39 (1)

Motivation: The gut microbiome changes rapidly under the influence of different factors such as age, dietary changes or medications to name just a few......

The COMER web server for protein analysis by homology

期刊: BIOINFORMATICS, 2023; 39 (1)

Sequence homology is a basic concept in protein evolution, structure and function studies. However, there are not many different tools and services fo......

The PRALINE database: protein and Rna humAn singLe nucleotIde variaNts in condEnsates

期刊: BIOINFORMATICS, 2023; 39 (1)

Biological condensates are membraneless organelles with different material properties. Proteins and RNAs are the main components, but most of their in......

PANACEA: network-based methods for pharmacotherapy prioritization in personalized oncology

期刊: BIOINFORMATICS, 2023; 39 (1)

Motivation: Identifying appropriate pharmacotherapy options from genomics results is a significant challenge in personalized oncology. However, comput......

Seqpac: a framework for sRNA-seq analysis in R using sequence-based counts

期刊: BIOINFORMATICS, 2023; 39 (4)

Motivation: Feature-based counting is commonly used in RNA-sequencing (RNA-seq) analyses. Here, sequences must align to target features (like genes or......

Population-based change-point detection for the identification of homozygosity islands

期刊: BIOINFORMATICS, 2023; 39 (4)

Motivation This work is motivated by the problem of identifying homozygosity islands on the genome of individuals in a population. Our method directly......

The ACPYPE web server for small-molecule MD topology generation

期刊: BIOINFORMATICS, 2023; 39 (6)

Motivation: The generation of parameter files for molecular dynamics (MD) simulations of small molecules that are suitable for force fields commonly a......

Consistency enhancement of model prediction on document-level named entity recognition

期刊: BIOINFORMATICS, 2023; 39 (6)

Biomedical named entity recognition (NER) plays a crucial role in extracting information from documents in biomedical applications. However, many of t......

COmic: convolutional kernel networks for interpretable end-to-end learning on (multi-)omics data

期刊: BIOINFORMATICS, 2023; 39 ()

Motivation: The size of available omics datasets is steadily increasing with technological advancement in recent years. While this increase in sample ......

MEvA-X: a hybrid multiobjective evolutionary tool using an XGBoost classifier for biomarkers discovery on biomedical datasets

期刊: BIOINFORMATICS, 2023; 39 (7)

Motivation Biomarker discovery is one of the most frequent pursuits in bioinformatics and is crucial for precision medicine, disease prognosis, and dr......

LPF: a framework for exploring the wing color pattern formation of ladybird beetles in Python

期刊: BIOINFORMATICS, 2023; 39 (7)

Summary Biological pattern formation is one of the complex system phenomena in nature, requiring theoretical analysis based on mathematical modeling a......

otargen: GraphQL-based R package for tidy data accessing and processing from Open Targets Genetics

期刊: BIOINFORMATICS, 2023; 39 (8)

Motivation: Open Target Genetics is a comprehensive resource portal that offers variant-centric statistical evidence, enabling the prioritization of c......

Extending protein interaction networks using proteoforms and small molecules

期刊: BIOINFORMATICS, 2023; 39 (10)

Motivation Biological network analysis for high-throughput biomedical data interpretation relies heavily on topological characteristics. Networks are ......

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