期刊： NATURE REVIEWS IMMUNOLOGY, 2021; 21 (9)
The cGAS-STING signalling pathway has emerged as a key mediator of inflammation in the settings of infection, cellular stress and tissue damage. Under......
期刊： NATURE REVIEWS IMMUNOLOGY, ; ()
Risk of severe coronavirus disease 2019 (COVID-19) after infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is increased in p......
期刊： NATURE REVIEWS IMMUNOLOGY, 2020; 20 (2)
The innate immune system has the capacity to detect 'non-self' molecules derived from pathogens, known as pathogen-associated molecular patterns, via ......
期刊： NATURE REVIEWS IMMUNOLOGY, 2020; 20 (3)
The gasdermins are a family of recently identified pore-forming effector proteins that cause membrane permeabilization and pyroptosis, a lytic pro-inf......
期刊： NATURE REVIEWS IMMUNOLOGY, 2020; 20 (10)
The COVID-19 pandemic is shining a spotlight on the field of immunology like never before. To appreciate the diverse ways in which immunologists have ......
期刊： NATURE REVIEWS IMMUNOLOGY, 2019; 19 (1)
Protection against microbial infection in eukaryotes is provided by diverse cellular and molecular mechanisms. Here, we present a comparative view of ......
期刊： NATURE REVIEWS IMMUNOLOGY, 2019; 19 (7)
Innate immune cells have complex signalling pathways for sensing pathogens and initiating innate immune responses against infection. These pathways ar......
期刊： NATURE REVIEWS IMMUNOLOGY, 2019; 19 (11)
Immunotherapies are yielding effective treatments for several previously untreatable cancers. Still, the identification of suitable antigens specific ......
期刊： NATURE REVIEWS IMMUNOLOGY, 2018; 18 (11)
Macrophages are immune cells with important roles in tissue homeostasis, inflammation and pathologies. Hence, macrophage populations represent promisi......
期刊： NATURE REVIEWS IMMUNOLOGY, 2018; 18 (3)
The vasculature of tumours is highly abnormal and dysfunctional. Consequently, immune effector cells have an impaired ability to penetrate solid tumou......
期刊： NATURE REVIEWS IMMUNOLOGY, 2018; 18 (9)
Are antibodies important for protection against tuberculosis? The jury has been out for more than 100 years. B cell depletion in experimental Mycobact......
