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Serum IgG4 elevation in SAPHO syndrome: does it unmask a disease activity marker?

期刊: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY, 2020; 38 (1)

Objective SAPHO syndrome is a rare inflammatory disorder with multiple phenotypes, including synovitis, acne, pustulosis, hyperostosis, and osteitis. ......

Adiponectin promotes fibroblast-like synoviocytes producing interleukin-6 to enhance T follicular helper cells response in rheumatoid arthritis

期刊: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY, 2020; 38 (1)

Objective Rheumatoid arthritis (RA) is characterised by the overproduction of autoantibodies such as rheumatoid factor (RF) and anti-cyclic citrullina......

Natural killer cells and their function in Takayasu's arteritis

期刊: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY, 2020; 38 (2)

Objective. Takayasu's arteritis (TAK) is a chronic, large-vessel systemic vas minis. Immune inflammatory response plays a crucial role in the pathogen......

Contribution of Th2-like Treg cells to the pathogenesis of Takayasu's arteritis

期刊: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY, 2020; 38 (2)

Objectives. Takayasu's arteritis (TAK) involves inflammatory vasculitis of large vessels and mainly affects the aorta and its major branches. Abnormal......

The potential role of leflunomide in inhibiting vascular fibrosis by down-regulating type-II macrophages in Takayasu's arteritis

期刊: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY, 2020; 38 (2)

Objective. Inflammatory fibrosis of aortic lesions promoted by type II macrophages (M2) is one of the most serious incidents in Takayasu's arteritis (......

Aneurysms in Takayasu's arteritis: a retrospective study of Chinese patients

期刊: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY, 2020; 38 (2)

Objective. Aneurysm formation can cause life-threatening complications in Takayasu's arteritis (TAK). The objective of this study was to evaluate the ......

Digestive involvement in primary Sjogren's syndrome: analysis from the Sjogrenser registry

期刊: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY, 2020; 38 (4)

Objective. Digestive involvement (DI) has been reported in 10-30% of primary Sjogren's syndrome (pSS) patients, and few studies have systematically an......

Pathogenesis of primary Sjogren's syndrome beyond B lymphocytes

期刊: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY, 2020; 38 (4)

Primary Sjogren's syndrome (pSS) is a chronic autoimmune disorder affecting exocrine glands of the body, prevalently lacrimal and salivary glands. The......

Evaluation of soluble CD25 as a clinical and autoimmune biomarker in primary Sjogren's syndrome

期刊: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY, 2020; 38 (4)

Objective. Serum soluble CD25 (sCD25) is associated with T cell activation and regarded as a marker of disease activity in autoimmune disorders. The a......

Systemic phenotype related to primary Sjogren's syndrome in 279 patients carrying isolated anti-La/SSB antibodies

期刊: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY, 2020; 38 (4)

Objective. To evaluate the systemic phenotype associated with the presence of isolated anti-La/SSB antibodies in a large international registry of pat......

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