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Perinatal Antibiotic Exposure Affects the Transmission between Maternal and Neonatal Microbiota and Is Associated with Early-Onset Sepsis

期刊: MSPHERE, 2020; 5 (1)

Intrapartum antibiotic prophylaxis reduces the risk of infection to a mother and neonate, but antibiotic-mediated maternal and neonatal microbiota dys......

Age-Related Variation of Bacterial and Fungal Communities in Different Body Habitats across the Young, Elderly, and Centenarians in Sardinia

期刊: MSPHERE, 2020; 5 (1)

Human body microbes interact with the host, forming microbial communities that are in continual flux during the aging process. Previous studies have m......

Acute Sleep-Wake Cycle Shift Results in Community Alteration of Human Gut Microbiome

期刊: MSPHERE, 2020; 5 (1)

Disturbances of sleep and the underlying circadian rhythm are related to many human diseases, such as obesity, diabetes, cardiovascular disorders, and......

Morphology and Transcriptome Analysis of Nosema bombycis Sporoplasm and Insights into the Initial Infection of Microsporidia

期刊: MSPHERE, 2020; 5 (1)

Microsporidia are obligate intracellular parasites that infect a wide variety of host organisms, including humans. The sporoplasm is the initial stage......

Nucleotide Excision Repair Protein Rad23 Regulates Cell Virulence Independent of Rad4 in Candida albicans

期刊: MSPHERE, 2020; 5 (1)

In the pathogenic yeast Candida albicans, the DNA damage response contributes to pathogenicity by regulating cell morphology transitions and maintaini......

Different Types of Atrial Fibrillation Share Patterns of Gut Microbiota Dysbiosis

期刊: MSPHERE, 2020; 5 (2)

Dysbiotic gut microbiota (GM) and disordered metabolic patterns are known to be involved in the clinical expression of atrial fibrillation (AF). Howev......

Cross-Feeding between Members of Thauera spp. and Rhodococcus spp. Drives Quinoline-Denitrifying Degradation in a Hypoxic Bioreactor

期刊: MSPHERE, 2020; 5 (2)

The complex bacterial community in a quinoline-degrading denitrifying bioreactor is predominated by several taxa, such as Thauera and Rhodococcus. How......

Allelic-Specific Regulation of xCT Expression Increases Susceptibility to Tuberculosis by Modulating microRNA-mRNA Interactions

期刊: MSPHERE, 2020; 5 (2)

xCT forms part of the x(c)(-) cysteine-glutamate antiporter which inhibits antimicrobial inflammatory immune functions and thus increases susceptibili......

Isolation and Characterization of Ochrobactrum tritici for Penicillin V Potassium Degradation

期刊: MSPHERE, 2020; 5 (2)

Substantial concentrations of penicillin V potassium (PVK) have been found in livestock manure, soil, and wastewater effluents, which may pose potenti......

New Mutations Involved in Colistin Resistance in Acinetobacter baumannii

期刊: MSPHERE, 2020; 5 (2)

Colistin is used as the "last resort" to treat infections caused by multidrug-resistant Acinetobacter baumannii, which is at the top of the World Heal......

Prevalence and Characteristics of Extended-Spectrum-beta-Lactamase-Producing and Carbapenemase-Producing Enterobacteriaceae from Freshwater Fish and Pork in Wet Markets of Hong Kong

期刊: MSPHERE, 2020; 5 (2)

This study identified and characterized extended-spectrum-beta-lactamase-producing Enterobacteriaceae (ESBL-E) and carbapenemase-producing Enterobacte......

Bazedoxifene Suppresses Intracellular Mycobacterium tuberculosis Growth by Enhancing Autophagy

期刊: MSPHERE, 2020; 5 (2)

Tuberculosis (TB) is still the leading killer caused by Mycobacterium tuberculosis infection. There is a clear need for new treatment strategy against......

Molecular Mechanisms of Phosphate Stress Activation of Pseudomonas aeruginosa Quorum Sensing Systems

期刊: MSPHERE, 2020; 5 (2)

The hierarchical quorum sensing (QS) systems of Pseudomonas aeruginosa, consisting of las, pqs, and rhl, coordinate the expression of bacterial virule......

Novel IncR/IncP6 Hybrid Plasmid pCRE3-KPC Recovered from a Clinical KPC-2-Producing Citrobacter braakii Isolate

期刊: MSPHERE, 2020; 5 (2)

Klebsiella pneumoniae carbapenemase (KPC)-producing Enterobacteriaceae have become widespread in hospitals and the environment. Here, we describe a bl......

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