期刊: JOURNAL OF LEUKOCYTE BIOLOGY, 2022; 111 (1)
The immune system plays a crucial role in the response against severe acute respiratory syndrome coronavirus 2 with significant differences among pati......
期刊: JOURNAL OF LEUKOCYTE BIOLOGY, 2022; 111 (4)
Sarcoidosis is a systemic inflammatory disease mainly affecting the lungs. The hallmark of sarcoidosis are granulomas that are surrounded by activated......
期刊: JOURNAL OF LEUKOCYTE BIOLOGY, 2022; 111 (6)
Severe coronavirus disease 2019 (COVID-19) is characterized by lung injury, cytokine storm, and increased neutrophil-to-lymphocyte ratio (NLR). Curren......
期刊: JOURNAL OF LEUKOCYTE BIOLOGY, 2022; 112 (3)
Hodgkin lymphoma (HL) is a neoplastic disease in which the inflammatory microenvironment plays a pivotal role in the tumorigenesis. Neutrophilia is a ......
期刊: JOURNAL OF LEUKOCYTE BIOLOGY, 2022; 112 (4)
Small cell lung cancer (SCLC) is characterized by a high relapse rate, drug tolerance, and limited treatment choices. Chimeric antigen receptor (CAR)-......
期刊: JOURNAL OF LEUKOCYTE BIOLOGY, 2022; 112 (4)
Cystic fibrosis (CF) airways feature high extracellular levels of the IL-1 family of proinflammatory mediators. These mediators are cleavage products ......
期刊: JOURNAL OF LEUKOCYTE BIOLOGY, 2022; 111 (5)
Neutrophils are terminally differentiated, short-lived white blood cells critical for innate immunity. Although cyclin-dependent kinases (CDKs) are ty......
期刊: JOURNAL OF LEUKOCYTE BIOLOGY, 2022; 112 (3)
PI3K pathway plays a crucial role in dendritic cells (DCs) functions, as it regulates different cellular processes, such as maturation and cytokines p......
期刊: JOURNAL OF LEUKOCYTE BIOLOGY, 2022; 112 (3)
Clearance of airway intruders by immune cells is required to resolve infectious pneumonia. However, the molecular mechanisms underlying this process r......
期刊: JOURNAL OF LEUKOCYTE BIOLOGY, 2022; 112 (4)
IL-10-producing regulatory B (Breg) cells are well recognized for maintaining immune tolerance. The impaired Breg cell function with decreased IL-10-p......
期刊: JOURNAL OF LEUKOCYTE BIOLOGY, 2022; 112 (4)
Myeloid-derived suppressor cells (MDSCs) are a heterogeneous population of leukocytes that are important for tumorigenesis and tumor immunotherapy. Th......
期刊: JOURNAL OF LEUKOCYTE BIOLOGY, 2022; 112 (6)
Ulcerative colitis (UC) is characterized by cycles of active disease flare and inactive disease remission. During UC remission, IL-22 is up-regulated,......
期刊: JOURNAL OF LEUKOCYTE BIOLOGY, 2022; 111 (1)
The potential protective or pathogenic role of the adaptive immune response to SARS-CoV-2 infection has been vigorously debated. While COVID-19 patien......
期刊: JOURNAL OF LEUKOCYTE BIOLOGY, 2022; 112 (6)
The discovery of neutrophil subtypes has expanded what is known about neutrophil functions, yet there is still much to learn about the role of these s......