期刊: JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2023; 34 (2)
Background Translation shutdown is a hallmark of late-phase, sepsis-induced kidney injury. Methods for controlling protein synthesis in the kidney are......
期刊: JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2023; 34 (4)
Background G protein-coupled receptor kinase 4 (GRK4) is considered a central regulator of blood pressure through phosphorylation of renal dopaminergi......
期刊: JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2023; 34 (7)
Background Thiazide diuretics are associated with glucose intolerance and new-onset diabetes mellitus. Previous studies demonstrated that thiazides at......
期刊: JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2023; 34 (10)
Background Hypoxia drives kidney damage and progression of CKD. Although erythrocytes respond rapidly to hypoxia, their role and the specific molecule......
期刊: JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2023; 34 (12)
Significance StatementDialysis-requiring AKI (AKI-D) now accounts for more than 15% of outpatient hemodialysis initiations; over 30% of these patients......
期刊: JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2023; 34 (2)
Background The dysfunction of complement factor H (CFH), the main soluble complement negative regulator, potentiates various complement-induced renal ......
期刊: JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2023; 34 (8)
Background Hemodialysis (HD) induces left ventricular (LV) transient myocardial dysfunction. A complex interplay between linear deformations and torsi......
期刊: JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2023; 34 (1)
Background Thinned glomerular basement membrane (tGBM) lesions are not uncommon in IgA nephropathy (IgAN). Type IV collagen-built of alpha 3, alpha 4,......
期刊: JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2023; 34 (3)
Background Late diagnosis is a hurdle for treatment of AKI, but targeting AKI-CKD transition may improve outcomes. High mobility group box-1 (HMGB1) i......