筛选条件 共查询到500条结果
排序方式
Pan-cancer noncoding genomic analysis identifies functional CDC20 promoter mutation hotspots

期刊: ISCIENCE, 2021; 24 (4)

Noncoding DNA sequences occupy more than 98% of the human genome; however, few cancer noncoding drivers have been identified compared with cancer codi......

Apoferritin improves motor deficits in MPTP-treated mice by regulating brain iron metabolism and ferroptosis

期刊: ISCIENCE, 2021; 24 (5)

Iron deposition is one of the key factors in the etiology of Parkinson's disease (PD). Iron-free-apoferritin has the ability to store iron by combinin......

Structural basis of copper-efflux-regulator-dependent transcription activation

期刊: ISCIENCE, 2021; 24 (5)

The copper efflux regulator (CueR), a representative member of mercury resistance regulator (MerR) family metalloregulators, controls expression of co......

Nature-inspired robust hydrochromic film for dual anticounterfeiting

期刊: ISCIENCE, 2021; 24 (6)

Nature-inspired materials have been actively developed for anticounterfeiting applications. Among a variety of stimuli-responsive anticounterfeiting s......

Polymerizable metal-organic frameworks for the preparation of mixed matrix membranes with enhanced interfacial compatibility

期刊: ISCIENCE, 2021; 24 (6)

The preparation of flawless and defect-free mixed matrix membranes (MMMs) comprising metal-organic framework (MOF) and polymer is often difficult owin......

Cell type-specific and cross-population polygenic risk score analyses of MIR137 gene pathway in schizophrenia

期刊: ISCIENCE, 2021; 24 (7)

Cell type-specific pathway-based polygenic risk scores (PRSs) may better inform disease biology and improve the precision of PRS-based clinical predic......

SlBES1 promotes tomato fruit softening through transcriptional inhibition of PMEU1

期刊: ISCIENCE, 2021; 24 (8)

Fruit softening indicated by firmness determines the texture, transportability, and shelf life of tomato products. However, the regulatory mechanism u......

White matter network of oral word reading identified by network-based lesion-symptom mapping

期刊: ISCIENCE, 2021; 24 (8)

Oral word reading is supported by a neural subnetwork that includes gray matter regions and white matter tracts connected by the regions. Traditional ......

Dopamine receptor DOP-1 engages a sleep pathway to modulate swimming in C. elegans

期刊: ISCIENCE, 2021; 24 (4)

Animals require robust yet flexible programs to support locomotion. Here we report a pathway that connects the D1-like dopamine receptor DOP-1 with a ......

Facile, scalable, and adaptive infrared reflection towards soft systems by blowing a Janus rubber film

期刊: ISCIENCE, 2021; 24 (5)

Controllable IR-reflection systems can be applied to displays, adaptive military camouflages, thermalmanagements, andmany other fields. However, curre......

Blink-sensing glasses: A flexible iontronic sensing wearable for continuous blink monitoring

期刊: ISCIENCE, 2021; 24 (5)

Blink reflex has long been considered closely related to physiological states, from which abundant information on ocular health and activities can be ......

Criticality assessment of metal resources in China

期刊: ISCIENCE, 2021; 24 (6)

With the development of modern industries, the sustainability of critical resources has attracted worldwide attention considering the entire supply ch......

Ether-linked porphyrin covalent organic framework with broadband optical switch

期刊: ISCIENCE, 2021; 24 (6)

It is still a challenge to design and synthesize novel switchable optical materials with ultrafast nonlinear optical (NLO) response in a broad spectra......

A comparative study on the thermal runaway inhibition of 18650 lithium-ion batteries by different fire extinguishing agents

期刊: ISCIENCE, 2021; 24 (8)

Safety issue of lithium-ion batteries (LIBs) is always a concern. We have studied the inhabitation on thermal runaway (TR) and propagation of 18,650 L......

InVision: An optimized tissue clearing approach for three-dimensional imaging and analysis of intact rodent eyes

期刊: ISCIENCE, 2021; 24 (8)

The mouse eye is used to model central nervous system development, pathology, angiogenesis, tumorigenesis, and regenerative therapies. To facilitate t......

共500条页码: 1/34页15条/页