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Metagenomic profiling of the pro-inflammatory gut microbiota in ankylosing spondylitis

期刊: JOURNAL OF AUTOIMMUNITY, 2020; 107 ()

Objective: Gut dysbiosis has been reported implicated in ankylosing spondylitis (AS), a common chronic inflammatory disease mainly affects sacroiliac ......

Fine mapping of the MHC region identifies major independent variants associated with Han Chinese primary biliary cholangitis

期刊: JOURNAL OF AUTOIMMUNITY, 2020; 107 ()

The genetic association of primary biliary cholangitis with major histocompatibility complex (MHC) has been widely confirmed among different ethniciti......

LncRNA PVT1 links Myc to glycolytic metabolism upon CD4(+) T cell activation and Sjogren's syndrome-like autoimmune response

期刊: JOURNAL OF AUTOIMMUNITY, 2020; 107 ()

The hyperproliferation and hyperactivation of CD4(+) T cells in salivary gland tissue is a hallmark of Sjogren's syndrome (SS). However, the role of l......

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