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Activation of TRPV4 stimulates transepithelial K+ secretion in rat epididymal epithelium

期刊: MOLECULAR HUMAN REPRODUCTION, 2022; 28 (2)

The maturation of sperms is dependent on the coordinated interactions between sperm and the unique epididymal luminal milieu, which is characterized b......

JIF:3.459

Early pregnancy human decidua gamma/delta T cells exhibit tissue resident and specific functional characteristics

期刊: MOLECULAR HUMAN REPRODUCTION, 2022; 28 (8)

A successful pregnancy is a complicated process that builds upon two aspects of the maternal immune system that need to be balanced. As one of the ind......

JIF:3.459

Thermotaxis of mammalian sperm

期刊: MOLECULAR HUMAN REPRODUCTION, 2022; 28 (8)

Sperm are guided through the female reproductive tract. A temperature difference of about 2 degrees C exists between the storage site and fertilizatio......

JIF:3.459

Pathogenic variant in ACTL7A causes severe teratozoospermia characterized by bubble-shaped acrosomes and male infertility

期刊: MOLECULAR HUMAN REPRODUCTION, 2022; 28 (8)

Teratozoospermia is a common factor associated with male infertility. However, teratozoospermia characterized by bubble-shaped acrosomes (BSAs) has no......

JIF:3.459

GAS6-mediated dialogue between decidual stromal cells and macrophages is essential for early pregnancy maintenance by inducing M2-like polarization and cell proliferation of decidual macrophages

期刊: MOLECULAR HUMAN REPRODUCTION, 2022; 28 (3)

Maternal immunotolerance towards the semi-allogeneic foetus is critical for normal pregnancy (NP). As a secretory protein, growth arrest-specific fact......

JIF:3.459

In vivo promotion of primordial follicle activation by stem cell factor treatment in mice with premature ovarian insufficiency and advanced age

期刊: MOLECULAR HUMAN REPRODUCTION, 2022; 29 (1)

Dormant primordial follicles (PFs) are the most abundant reproductive resource in mammalian ovaries. With advances in the mechanism of study of the re......

JIF:3.459

Exosomes released from Sertoli cells contribute to the survival of Leydig cells through CCL20 in rats

期刊: MOLECULAR HUMAN REPRODUCTION, 2022; 28 (2)

Reciprocal communication between Sertoli and Leydig cells occurs in the testes; however, the detailed mechanisms involved are not completely understoo......

JIF:3.459

Elevated prohibitin 1 expression mitigates glucose metabolism defects in granulosa cells of infertile patients with endometriosis

期刊: MOLECULAR HUMAN REPRODUCTION, 2022; 28 (6)

Endometriosis is a common disease in women of childbearing age and is closely associated with female infertility. However, the pathogenesis of endomet......

JIF:3.459

Single-cell RNA sequencing reveals abnormal fluctuations in human eight-cell embryos associated with blastocyst formation failure

期刊: MOLECULAR HUMAN REPRODUCTION, 2022; 28 (1)

Infertility has become a global health issue, with the number of people suffering from the disease increasing year by year, and ART offering great pro......

JIF:3.459

Alteration of RNA modification signature in human sperm correlates with sperm motility

期刊: MOLECULAR HUMAN REPRODUCTION, 2022; 29 (9)

RNA modifications, which are introduced post-transcriptionally, have recently been assigned pivotal roles in the regulation of spermatogenesis and emb......

JIF:3.459

Macrophage-associated immune checkpoint CD47 blocking ameliorates endometriosis

期刊: MOLECULAR HUMAN REPRODUCTION, 2022; 28 (5)

Peritoneal macrophages play a significant role in the progression of endometriosis (EM), but their functional differentiation is still unclear, and th......

JIF:3.459

Nucleoporin37 may play a role in early embryo development in human and mice

期刊: MOLECULAR HUMAN REPRODUCTION, 2022; 28 (6)

Maternal-effect genes (MEGs) play an important role in maintaining the survival and development of mammalian embryos at the cleavage stage after ferti......

JIF:3.459

WDR87 interacts with CFAP47 protein in the middle piece of spermatozoa flagella to participate in sperm tail assembly

期刊: MOLECULAR HUMAN REPRODUCTION, 2022; 29 (1)

Spermatogenesis is a complex process that includes spermatogonia self-renewal, spermatocyte meiosis and spermatozoa assembly. Recent studies have reve......

JIF:3.459

Expression profiling and function analysis identified new microRNAs regulating cumulus expansion and apoptosis in cumulus cells

期刊: MOLECULAR HUMAN REPRODUCTION, 2022; 28 (1)

Although microRNAs (miRNAs) expressed in cumulus cells (CCs) may be used to select competent oocytes/embryos, only a limited number of such miRNAs has......

JIF:3.459

The roles of ADAMDEC1 in trophoblast differentiation during normal pregnancy and preeclampsia

期刊: MOLECULAR HUMAN REPRODUCTION, 2022; 28 (5)

Human cytotrophoblast (CTB) differentiation into syncytiotrophoblast (STB) is essential for placental formation and function. Understanding the molecu......

JIF:3.459

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