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In-vitro cytotoxicity and in-vivo antitumor activity of two platinum complexes with 1,3-dimethyl pentyl glycine ligand against breast cancer

期刊: JOURNAL OF INORGANIC BIOCHEMISTRY, 2023; 241 ()

Platinum (Pt) derivatives are good candidates for discovering new anti-tumor agents. The present research aims to explore the in-vivo and in-vitro ant......

Investigation of thiol compounds (L-cysteine, thioacetic acid and ethanethiol) with V(V) and V(IV) using combined spectroscopy and chromatography

期刊: JOURNAL OF INORGANIC BIOCHEMISTRY, 2023; 242 ()

The interactions of V(V) and L-cysteine, thioacetic acid and ethanethiol were studied in aqueous solution using chromatographic and spectral analysis.......

Reduction of metmyoglobin by inorganic disulfide species

期刊: JOURNAL OF INORGANIC BIOCHEMISTRY, 2023; 245 ()

The mechanism of the metal centered reduction of metmyoglobin (MbFeIII) by inorganic disulfide species has been studied by combined spectroscopic and ......

Organogold(III)-dithiocarbamate compounds and their coordination analogues as anti-tumor and anti-leishmanial metallodrugs

期刊: JOURNAL OF INORGANIC BIOCHEMISTRY, 2023; 247 ()

The limited chemical stability of gold(III)-based compounds in physiological environment has been a challenge in drug discovery, and organometallic ch......

Characterisation of the heme aqua-ligand coordination environment in an engineered peroxygenase cytochrome P450 variant

期刊: JOURNAL OF INORGANIC BIOCHEMISTRY, 2023; 249 ()

The cytochrome P450 enzymes (CYPs) are heme-thiolate monooxygenases that catalyse the insertion of an ox-ygen atom into the C-H bonds of organic molec......

Copper(II) complexes with 3,5-dihalogeno-salicylaldehydes: Synthesis, structure and interaction with DNA and albumins

期刊: JOURNAL OF INORGANIC BIOCHEMISTRY, 2023; 238 ()

Eight copper(II) complexes of 3,5-dichloro-salicyladehyde or 3,5-dibromo-salicyladehyde (3,5-diX-saloH, X = Br or Cl) were synthesized in the absence ......

GLB-3: A resilient, cysteine-rich, membrane-tethered globin expressed in the reproductive and nervous system of Caenorhabditis elegans

期刊: JOURNAL OF INORGANIC BIOCHEMISTRY, 2023; 238 ()

The popular genetic model organism Caenorhabditis elegans (C. elegans) encodes 34 globins, whereby the few that are well-characterized show divergent ......

Photophysical, photobiological, and biomolecule-binding properties of new tri-cationic meso-tri(2-thienyl)corroles with Pt(II) and Pd(II) polypyridyl derivatives

期刊: JOURNAL OF INORGANIC BIOCHEMISTRY, 2023; 242 ()

We report the synthesis and characterization of new tri-cationic corrole derivatives, containing Pt(II) or Pd(II) complexes attached at the peripheral......

How Cu(II) binding affects structure and dynamics of α-synuclein revealed by molecular dynamics simulations

期刊: JOURNAL OF INORGANIC BIOCHEMISTRY, 2023; 239 ()

We report accelerated molecular dynamics simulations of alpha-Synuclein and its complex with two Cu(II) ions bound to experimentally determined bindin......

Bis(benzimidazole)amino thio- and selenoether Iron(II) complexes as proton reduction electrocatalysts

期刊: JOURNAL OF INORGANIC BIOCHEMISTRY, 2023; 241 ()

Two novel Iron (II) complexes featuring tetrapodal bis(benzimidazole)amino thio- and selenoether ligands (LS and LSe) were synthesized, characterized,......

Antileishmanial effects and drugability characteristics of a heterocyclic copper complex: An in silico, in vitro and molecular study

期刊: JOURNAL OF INORGANIC BIOCHEMISTRY, 2023; 245 ()

Leishmaniasis caused by the protozoan Leishmania presents a severe illness, principally in tropical and subtropical areas. Antileishmanial metal compl......

Molecular and kinetic properties of copper nitrite reductase from Sinorhizobium meliloti 2011 upon substituting the interfacial histidine ligand coordinated to the type 2 copper active site for glycine

期刊: JOURNAL OF INORGANIC BIOCHEMISTRY, 2023; 241 ()

A copper-containing nitrite reductase catalyzes the reduction of nitrite to nitric oxide in the denitrifier Sino-rhizobium meliloti 2011 (SmNirK), a m......

Lysosome directed red light photodynamic therapy using glycosylated iron-(III) conjugates of boron-dipyrromethene

期刊: JOURNAL OF INORGANIC BIOCHEMISTRY, 2023; 244 ()

To overcome the drawbacks associated with chemotherapeutic and porphyrin-based photodynamic therapy (PDT) agents, the use of BODIPY (boron-dipyrrometh......

Study of the biological activity of photoactive bipyridyl-Ru(II) complexes containing 1,3,5-triaza-7-phosphaadamantane (PTA)

期刊: JOURNAL OF INORGANIC BIOCHEMISTRY, 2023; 246 ()

The water-soluble ruthenium complex cis-[Ru(dcbpyH)(2)(PTAH)(2)]Cl-2 center dot 3H(2)O (1) (dcbpy = 4,4'-dicarboxy-2,2'bipyridine; PTA = 1,3,5-triaza-......

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