期刊： NEUROTHERAPEUTICS, 2021; 18 (1)
Insomnia is a prevalent sleep problem associated with a constellation of negative health-related outcomes and significant socioeconomic burden. It com......
期刊： NEUROTHERAPEUTICS, 2021; 18 (2)
Glaucoma is a neurodegenerative disease that causes progressive, irreversible vision loss. Currently, intraocular pressure (IOP) is the only modifiabl......
Glucagon-like peptide-1 (GLP-1) receptor stimulation ameliorates parkinsonian motor and non-motor deficits in both experimental animals and patients; ......
During intracranial aneurysm embolization with the Pipeline embolization device (PED), ischemic and hemorrhagic complications have been observed in ca......
Gadolinium (Gd)-contrast MRI for reliable detection of blood-brain barrier (BBB) breakdown is widely used in neuromyelitis optica spectrum disorder (N......
Activated microglia can suppress neurite outgrowth and synapse recovery in the acute stage following traumatic brain injury (TBI). However, the underl......
Brain capillaries are crucial for cognitive functions by supplying oxygen and other nutrients to and removing metabolic wastes from the brain. Recent ......
Prostaglandin-E-2 (PGE(2)), an important mediator of inflammation, achieves its functions via four different G protein-coupled receptors (EP1, EP2, EP......
Adjuvant neuroprotective therapies for acute ischemic stroke (AIS) have demonstrated benefit in animal studies, albeit without human translation. We i......
Posttraumatic syringomyelia (PTS) is a serious condition of progressive expansion of spinal cord cysts, affecting patients with spinal cord injury yea......
Abnormal redox regulation is thought to contribute to schizophrenia (SCZ). Accumulating studies have shown that the plasma antioxidant enzyme activity......
期刊： NEUROTHERAPEUTICS, 2020; 17 (1)
There is currently no disease-modifying treatment for Huntington's disease (HD), which is characterized by chorea motor impairment and cognitive decli......
期刊： NEUROTHERAPEUTICS, 2020; 17 (2)
Tanshinone IIA (TSA), an important natural lipophilic diterpene compound from the traditional Chinese herbSalvia miltiorrhizaBunge, has long been wide......
期刊： NEUROTHERAPEUTICS, 2020; 17 (2)
Despite Alzheimer's disease (AD) being the most common neurodegenerative disorder worldwide, no FDA-approved disease-modifying treatments have been ap......
期刊： NEUROTHERAPEUTICS, 2020; 17 (2)
Depression, plus the accompanying memory impairment, is one of the leading causes of disability worldwide. Thus, there is a critical need to develop n......
