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Regulation of Synovial gd T Cell Ligand Expression by Mitochondrial Reactive Oxygen Species and Gasdermin-D

期刊: JOURNAL OF IMMUNOLOGY, 2023; 210 (1)

gd T cells reside at mucosal and epithelial barriers, and they often accumulate at sites of inflammation, both infectious and autoimmune, as well as i......

IL-10 Negatively Controls the Primary T Cell Response of Tilapia by Triggering the JAK1/STAT3/SOCS3 Axis That Suppresses NF-KB and MAPK/ERK Signaling

期刊: JOURNAL OF IMMUNOLOGY, 2023; 210 (3)

The braking mechanisms to protect the host from tissue damage and inflammatory disease caused by an overexuberant immune response are common in many T......

IFN-Induced Protein with Tetratricopeptide Repeats 2 Limits Autoimmune Inflammation by Regulating Myeloid Cell Activation and Metabolic Activity

期刊: JOURNAL OF IMMUNOLOGY, 2023; 210 (6)

Besides antiviral functions, type I IFN expresses potent anti-inflammatory properties and is being widely used to treat certain autoimmune conditions,......

Multistep IgE Mast Cell Desensitization Is a Dose- and Time-Dependent Process Partially Regulated by SHIP-1

期刊: JOURNAL OF IMMUNOLOGY, 2023; 210 (6)

Multistep mast cell desensitization blocks the release of mediators following IgE crosslinking with increasing doses of Ag. Although its in vivo appli......

IL-1/MyD88-Dependent G-CSF and IL-6 Secretion Mediates Postburn Anemia

期刊: JOURNAL OF IMMUNOLOGY, 2023; 210 (7)

The anemia of critical illness (ACI) is a nearly universal pathophysiological consequence of burn injury and a primary reason burn patients require ma......

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