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Proteomic analyses of plasma-derived exosomes in immunoglobulin (Ig) G4-related disease and their potential roles in B cell differentiation and tissue damage

期刊： JOURNAL OF AUTOIMMUNITY, 2021; 122 ()

Objective: To investigate the proteomic profiles of plasma exosomes isolated from patients with immunoglobulin (Ig) G4-related disease (IgG4-RD) and t......

Transcriptome landscape of double negative T cells by single-cell RNA sequencing

期刊： JOURNAL OF AUTOIMMUNITY, 2021; 121 ()

CD4 and CD8 coreceptor double negative TCR alpha beta+ T (DNT) cells are increasingly being recognized for their critical and diverse roles in the imm......

An autoantigen profile of human A549 lung cells reveals viral and host etiologic molecular attributes of autoimmunity in COVID-19

期刊： JOURNAL OF AUTOIMMUNITY, 2021; 120 ()

We aim to establish a comprehensive COVID-19 autoantigen atlas in order to understand autoimmune diseases caused by SARS-CoV-2 infection. Based on the......

A novel humanized cutaneous lupus erythematosus mouse model mediated by IL-21-induced age-associated B cells

期刊： JOURNAL OF AUTOIMMUNITY, 2021; 123 ()

Cutaneous lupus erythematosus (CLE) is a relapsing autoimmune disease, but key elements that drive disease initiation and progression remain elusive. ......

Guideline for the diagnosis, treatment and long-term management of cutaneous lupus erythematosus

期刊： JOURNAL OF AUTOIMMUNITY, 2021; 123 ()

Cutaneous lupus erythematosus (CLE) is an inflammatory, autoimmune disease encompassing a broad spectrum of subtypes including acute, subacute, chroni......

Human papillomavirus symptomatic infection associated with increased risk of new-onset alopecia areata: A nationwide population-based cohort study

期刊： JOURNAL OF AUTOIMMUNITY, 2021; 119 ()

Background: We investigated the correlation between a history of human papillomavirus (HPV) infection and alopecia areata risk. Methods: The study coh......

Profiling of the immune repertoire in COVID-19 patients with mild, severe, convalescent, or retesting-positive status

期刊： JOURNAL OF AUTOIMMUNITY, 2021; 118 ()

Forty-seven samples of peripheral blood mononuclear cells from four groups of coronavirus disease (COVID)-19 patients (mild, severe, convalescent, ret......

The amino acid variants in HLA II molecules explain the major association with adult-onset Still's disease in the Han Chinese population

期刊： JOURNAL OF AUTOIMMUNITY, 2021; 116 ()

Adult-onset Still's disease (AOSD) is a rare autoinflammatory disease with systemic involvement, and its pathophysiology remains unclear. Genome-wide ......

Identification of a primary antigenic target of epitope spreading in endemic pemphigus foliaceus

期刊： JOURNAL OF AUTOIMMUNITY, 2021; 116 ()

Epitope spreading is an important mechanism for the development of autoantibodies (autoAbs) in autoimmune diseases. The study of epitope spreading in ......

Resistant starch intake alleviates collagen-induced arthritis in mice by modulating gut microbiota and promoting concomitant propionate production

期刊： JOURNAL OF AUTOIMMUNITY, 2021; 116 ()

Gut dysbiosis precedes clinic symptoms in rheumatoid arthritis (RA) and has been implicated in the initiation and persistence of RA. The early treatme......

Early diagnosis and treatment for Sjogren's syndrome: current challenges, redefined disease stages and future prospects

期刊： JOURNAL OF AUTOIMMUNITY, 2021; 117 ()

There are some challenges and unmet needs in the early diagnosis and management of Sjogren's syndrome (SjS) such as prominent glandular dysfunction at......

The B cell response to both protein and nucleic acid antigens displayed on apoptotic cells are dependent on endosomal pattern recognition receptors

期刊： JOURNAL OF AUTOIMMUNITY, 2021; 117 ()

In systemic autoimmune diseases such as systemic lupus erythematosus (SLE), B cell tolerance is lost and there is a production of autoantibodies that ......

Metagenomic profiling of the pro-inflammatory gut microbiota in ankylosing spondylitis

期刊： JOURNAL OF AUTOIMMUNITY, 2020; 107 ()

Objective: Gut dysbiosis has been reported implicated in ankylosing spondylitis (AS), a common chronic inflammatory disease mainly affects sacroiliac ......

Fine mapping of the MHC region identifies major independent variants associated with Han Chinese primary biliary cholangitis

期刊： JOURNAL OF AUTOIMMUNITY, 2020; 107 ()

The genetic association of primary biliary cholangitis with major histocompatibility complex (MHC) has been widely confirmed among different ethniciti......

LncRNA PVT1 links Myc to glycolytic metabolism upon CD4(+) T cell activation and Sjogren's syndrome-like autoimmune response

期刊： JOURNAL OF AUTOIMMUNITY, 2020; 107 ()

The hyperproliferation and hyperactivation of CD4(+) T cells in salivary gland tissue is a hallmark of Sjogren's syndrome (SS). However, the role of l......

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