期刊： EXPERT OPINION ON INVESTIGATIONAL DRUGS, 2021; 30 (9)
Introduction: Osteoarthritis (OA) is a serious and incurable disease leading the disability. Surgical treatment is the last but not necessarily the be......
期刊： EXPERT OPINION ON INVESTIGATIONAL DRUGS, ; ()
Background: The pharmacokinetics (PK), safety, and tolerability profiles of ZSP1601, a first-in-class pan-phosphodiesterase (PDE) inhibitor, were eval......
期刊： EXPERT OPINION ON INVESTIGATIONAL DRUGS, 2021; 30 (3)
Background MT-1207 is a novel multitarget blocker of alpha 1 receptor, 5-HT2A receptor, and calcium channel that is currently under development for th......
期刊： EXPERT OPINION ON INVESTIGATIONAL DRUGS, 2021; 30 (1)
Introduction: Cyclin-dependent kinase 7 (CDK7) is a part of the CDK-activating kinase family (CAK) which has a key role in the cell cycle and transcri......
期刊： EXPERT OPINION ON INVESTIGATIONAL DRUGS, 2021; 30 (3)
Background & Aims: TQ-A3334, a selective, oral toll-like receptor (TLR)-7 agonist, is being developed to treat chronic hepatitis B (CHB). This stu......
期刊： EXPERT OPINION ON INVESTIGATIONAL DRUGS, 2020; 29 (7)
Objectives Recombinant human HER2 monoclonal antibody for injection (AK-HER2) is a potential biosimilar of trastuzumab (Herceptin (R)). This phase ROM......
期刊： EXPERT OPINION ON INVESTIGATIONAL DRUGS, 2020; 29 (12)
Introduction: Non-small cell lung cancer (NSCLC) accounts for most lung cancers worldwide and has a poor prognosis at later stages; programmed cell de......
期刊： EXPERT OPINION ON INVESTIGATIONAL DRUGS, 2020; 29 (4)
Introduction: This review evaluates the novel strategy of treating Alzheimer's and Parkinson's disease (AD and PD) withdrugs that initially have been ......
期刊： EXPERT OPINION ON INVESTIGATIONAL DRUGS, 0; ()
Introduction: Rheumatoid arthritis (RA) is a chronic, refractory disorder caused by autoimmunity in the synovial joints. Disease-modifying anti-rheuma......
期刊： EXPERT OPINION ON INVESTIGATIONAL DRUGS, 2019; 28 (1)
Introduction: Multiple pathways are involved in the pathogenesis of systemic lupus erythematosus (SLE). The Janus kinase-signal transducers and activa......
期刊： EXPERT OPINION ON INVESTIGATIONAL DRUGS, 2019; 28 (5)
Introduction: Influenza viral ribonucleoprotein complexes (vRNPs) play a key role in viral transcription and replication; hence, the recent developmen......
期刊： EXPERT OPINION ON INVESTIGATIONAL DRUGS, 2019; 28 (10)
Introduction: Fibroblast growth factor receptor 2 (FGFR2) is a highly conserved transmembrane tyrosine kinase receptor. FGFR2 dysregulation occurs in ......
期刊： EXPERT OPINION ON INVESTIGATIONAL DRUGS, 2019; 28 (10)
Introduction: Acetyl-CoA Carboxylase (ACC) is an essential rate-limiting enzyme in fatty acid metabolism. For many years, ACC inhibitors have gained g......
期刊： EXPERT OPINION ON INVESTIGATIONAL DRUGS, 2018; 27 (11)
Introduction: Osteoarthritis (OA) is the leading cause of pain, loss of function, and disability among elderly, with the knee the most affected joint.......
