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Sirt1 Mediates Vitamin D Deficiency-Driven Gluconeogenesis in the Liver via mTorc2/Akt Signaling

期刊: JOURNAL OF DIABETES RESEARCH, 2022; 2022 ()

As an active form of vitamin D (VD), 1,25-dihydroxyvitamin D (1,25(OH)(2)D-3) is involved in the development of many metabolic diseases, such as diabe......

JIF:3.558

Serum Bile Acid Profiles in Latent Autoimmune Diabetes in Adults and Type 2 Diabetes Patients

期刊: JOURNAL OF DIABETES RESEARCH, 2022; 2022 ()

Background. Impaired bile acid (BA) metabolism has been associated with the progression of type 2 diabetes (T2D). However, the contribution of BAs to ......

JIF:3.558

RNA-Binding Proteins and Alternative Splicing Genes Are Coregulated in Human Retinal Endothelial Cells Treated with High Glucose

期刊: JOURNAL OF DIABETES RESEARCH, 2022; 2022 ()

To explore the relevant RNA-binding proteins (RBPs) and alternative splicing events (ASEs) in diabetic retinopathy (DR). We devised a comprehensive wo......

JIF:3.558

Improvement of Lipotoxicity-Induced Islet beta Cellular Insulin Secretion Disorder by Osteocalcin

期刊: JOURNAL OF DIABETES RESEARCH, 2022; 2022 ()

Background. Osteocalcin (OCN) has been proved to be closely related with the development of type 2 diabetes mellitus (T2DM). We aimed to study if OCN ......

JIF:3.558

Association of Sirtuin 1 Gene Polymorphisms with the Risk of Coronary Heart Disease in Chinese Han Patients with Type 2 Diabetes Mellitus

期刊: JOURNAL OF DIABETES RESEARCH, 2022; 2022 ()

Aims. To explore the associations between polymorphisms in SIRT1 and coronary heart disease (CHD) risk in Chinese Han patients with type 2 diabetes (T......

JIF:3.558

Causes and Risk Factors of Repeated Hospitalization among Patients with Diabetic Retinopathy

期刊: JOURNAL OF DIABETES RESEARCH, 2022; 2022 ()

Purpose. To identify the causes and risk factors of repeated hospitalization among patients with diabetic retinopathy (DR). Methods. Our study retrosp......

JIF:3.558

UTP14A, DKC1, DDX10, PinX1, and ESF1 Modulate Cardiac Angiogenesis Leading to Obesity-Induced Cardiac Injury

期刊: JOURNAL OF DIABETES RESEARCH, 2022; 2022 ()

Background. This study is aimed at exploring the key genes and the possible mechanism of heart damage caused by obesity. Methods. We analyzed the GSE9......

JIF:3.558

Clinical Characteristics of Target Organ Damage in Primary Aldosteronism with or without Metabolic Syndrome

期刊: JOURNAL OF DIABETES RESEARCH, 2022; 2022 ()

The aim of this study is to investigate the prevalence of metabolic disorders in patients with primary aldosteronism (PA) and target organ damage (TOD......

JIF:3.558

Association between Vitamin D Status and Mortality among Adults with Diabetic Kidney Disease

期刊: JOURNAL OF DIABETES RESEARCH, 2022; 2022 ()

Objective. Emerging evidence demonstrates that vitamin D status contributes to the incidence of diabetic kidney disease (DKD). However, the causal rel......

JIF:3.558

Effect of Hypertension, Waist-to-Height Ratio, and Their Transitions on the Risk of Type 2 Diabetes Mellitus: Analysis from the China Health and Retirement Longitudinal Study

期刊: JOURNAL OF DIABETES RESEARCH, 2022; 2022 ()

Background. Diabetes is a major reason of death and disability worldwide and frequently coexists with hypertension and central obesity. This study is ......

JIF:3.558

Interaction of Hypertension and Insulin Resistance Exacerbates the Occurrence of Diabetes Mellitus in Healthy Individuals

期刊: JOURNAL OF DIABETES RESEARCH, 2022; 2022 ()

Objective. Hypertension and type 2 diabetes are common complications. Patients with hypertension often show insulin resistance. The purpose of this st......

JIF:3.558

Multiomics Integrated Analysis Identifies SLC24A2 as a Potential Link between Type 2 Diabetes and Cancer

期刊: JOURNAL OF DIABETES RESEARCH, 2022; 2022 ()

Background. So far, type 2 diabetes (T2D) is considered as an independent risk factor for various cancers, but the underlying mechanism remains unclea......

JIF:3.558

Shenlian (SL) Decoction, a Traditional Chinese Medicine Compound, May Ameliorate Blood Glucose via Mediating the Gut Microbiota in db/db Mice

期刊: JOURNAL OF DIABETES RESEARCH, 2022; 2022 ()

Shenlian (SL) decoction is a herbal formula composed of Coptis and ginseng, of which berberine and ginsenoside are the main constituents. Even though ......

JIF:3.558

2'- O-Methylperlatolic Acid Enhances Insulin-Regulated Blood Glucose-Lowering Effect through Insulin Receptor Signaling Pathway

期刊: JOURNAL OF DIABETES RESEARCH, 2022; 2022 ()

Purpose. Insulin receptor (InsR) sensitizers represent a new type of therapeutic agent for the treatment of diabetes, with 2'-O-methylperlatolic acid ......

JIF:3.558

Type 2 Diabetic Mellitus Inhibits Skin Renewal through Inhibiting WNT-Dependent Lgr5+Hair Follicle Stem Cell Activation in C57BL/6 Mice

期刊: JOURNAL OF DIABETES RESEARCH, 2022; 2022 ()

Background. Hair follicles are important accessory organs of the skin, and it is important for skin renewal and performs variety of important function......

JIF:3.558

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